Aim of study The NLR is a simple and inexpensive parameter that is useful as a marker of subclinical inflammation. The purpose of this study was to investigate the clinical characteristics of patients diagnosed with acute cerebral ischemia at the time of initial evaluation in the emergency department. Patients and methods The study was designed as a multicentre cross‐sectional study of acute ischemic stroke patients. Neurological evaluations were assessed using the NIHSS and mRS. Evaluations included the results of patients’ laboratory tests performed at the time of presentation to the emergency department. Results Seven hundred and thirty‐five ischemic stroke patients were included in the study. Stroke cases assessed by the mRS as mild or severe showed significant differences with respect to age, leukocyte counts, neutrophil counts, NLR, LDL cholesterol values, and serum glucose values (P = .001). When analysed using NIHSS, lymphocyte levels were significantly higher in very severe stroke cases compared with mild, moderate, and severe cases. NLR was also significantly higher in very severe stroke cases and severe stroke cases as compared with the mild and moderate stroke groups. Neurological evaluations assessed using the mRS showed a mild positive correlation with neutrophil and leukocyte count and a weak correlation with the NLR. Conclusion The NLR exhibited a significant correlation with the results of the mRS and NIHSS. The NLR measured in the very early period was also significantly associated with clinical condition. These results suggest that high NLR values may be a marker of stroke’ severity. What's known Stroke is an important disease that has a significant impact on mortality and morbidity and is closely related to the aging world population. In recent years, highly innovative approaches have been developed in the treatment of stroke. Although a long distance has been covered in the early diagnosis of stroke, the ability to predict the severity of the disease with many parameters is still up to date. What's new At the time of admission, in the absence of infection, parameters such as leukocytelymphocyte count and NLR may be telling about stroke severity. Demonstrating the utility of these simple, practical, inexpensive and naninvasive parameters to predict stroke severity can contribute to the scoring to be established at the time of initial diagnosis.

Introduction and Aim Stroke is the leading cause of disability in adults and the second most common cause of death, at a rate of 11.8% worldwide. The purpose of this study was to examine the etiological, demographic, and clinical characteristics of patients admitted to hospital due to acute strokes. Materials and Methods This multi-center study retrieved information for all patients admitted to hospital due to an acute cerebrovascular event over a six-month period, and sociodemographic, etiological, and clinical characteristics were recorded. Results A total of 1136 patients, 520 of whom were women (45.7%), with a mean age of 70.3 ± 12.8 years, were included in the study. Of these, 967 were diagnosed with ischemic stroke (IS) (85.1%), 99 with hemorrhagic stroke (HS) (8.7%), and 70 with transient ischemic attack (6.1%). The most common risk factor for stroke was hypertension (73%). Carotid disease and hyperlipidemia rates were higher in patients with HS. Numbers of functionally dependent patients with severe neurological status according to the National Institutes of Health Stroke Scale and modified Rankin scale were significantly higher in the HS group (p <0.001). When IS was classified according to the Trial of Org 10172 in Acute Stroke Treatment, small vessel disease emerged as the nost common cause (41%). The most common lesion localizations were the parietal lobe (23%) in the IS group and the thalamus (35.3%) in the HS group. Eighty-eight patients (7.7%), 62 (6.4%) in the ischemic subgroup, and 26 (26.3%) in the hemorrhagic subgroup, died within the first month. Conclusion Current and accurate evaluations of stroke etiology are essential for stroke prevention and treatment planning. The present study, shows that no change occurred in the etiology of stroke and epidemiological characteristics and that accurate identification of modifiable stroke risk factors is still a major goal.

Background and Objectives: The pathophysiology of mild cognitive impairment in Parkinson’s disease (PD-MCI) is still not fully elucidated. It has been shown in a few studies in the literature that volume loss in the occipital, parietal and frontal cortices and atrophy in the hippocampus of PD-MCI patients can occur in the early stages of PD. The aim of this study was to evaluate the relationship between gray and white matter volumes and different neuropsychological tests and volumetric magnetic resonance imaging parameters in patients with mild cognitive impairment in Parkinson’s disease (PD-MCI). Materials and Methods: Twenty-six PD-MCI and twenty-six healthy elderly (HC) were included in this study. Results: We found that Mini Mental State Examination, Trail Making Test Part A, Clock Drawing Test, Benton Line Judgment Orientation Test and pentagon figure-copying scores were impaired in PD-MCI patients due to the decrease in brain volumes. Conclusions: Our study revealed that among PD-MCI patients, there was a more noticeable decline in White matter volume (WMV) based on volumetric Magnetic Resonance Imaging (MRI) compared to the localized loss of GMV. We think that these abnormal neuropsychological tests in PD-MCI patients can be used as pretests in the evaluation of the stage of transition to dementia.

Objectives: This study aimed to investigate methyl alcohol poisoning cases in Izmir. Patients and methods: The retrospective study included 15 patients (14 males, 1 female; mean age: 56.1±9.3 years; range, 40 to 71 years) diagnosed with methyl alcohol poisoning due to counterfeit alcoholic beverage consumption between October 1, 2020, and October 30, 2020. Patients were grouped according to survival. The demographic and clinical data, including the Acute Physiology and Chronic Health Evaluation II scoring and Glasgow Coma Scale scores, were compared. Results: Of the patients, eight (53.3%) died, and seven survived. There was no significant difference between deceased and surviving patients regarding optical nerve involvement, mechanical ventilation need, and dyspnea (p=0.057, p=0.467, and p=0.467, respectively). On the other hand, a significant difference was observed between deceased and surviving patients regarding radiological imaging, visual impairment, gastrointestinal symptoms, and vasopressor agent need (p=0.044, p<0.001, p=0.011, and p=0.026, respectively). Mortality was significantly correlated with vasopressor agent needs, Acute Physiology and Chronic Health Evaluation II score, and Glasgow Coma Scale score (p=0.009; r=0.645, p=0.009; r=–0.652, p=0.008; and r=0.562, p=0.029; respectively). Conclusion: Methyl alcohol poisoning is a common and even accelerating problem in Türkiye and results in high mortality and morbidity. Clinical, social, and economic strategies should be developed by national authorities to combat the issue.