Background/Objectives: Breast cancer remains the most common malignancy among women worldwide, with many patients experiencing persistent psychological symptoms that extend beyond active treatment. Among these, sleep disturbances, anxiety, and depression frequently co-occur and can significantly impair quality of life and treatment adherence. This study aimed to assess the prevalence of poor sleep quality and examine its associations with anxiety and depression in a large cohort of Turkish women with breast cancer. Additionally, the study sought to identify sociodemographic and clinical predictors of sleep disturbance. Methods: In this cross-sectional study, 601 women with histologically confirmed breast cancer who were undergoing or had completed active treatment were recruited from a tertiary oncology center in Turkey between January 2023 and December 2023. The mean age of participants was 54 years (range 25–83). More than half of the patients were postmenopausal (56.3%), and 6% had stage IV disease. Sleep quality and psychological distress were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Hospital Anxiety and Depression Scale (HADS). Descriptive statistics, correlation analyses, and multivariate regression models were employed to identify significant predictors. Results: Poor sleep quality (PSQI > 5) was identified in 33.2% of participants. Patients with poor sleep reported significantly higher anxiety and depression scores (p < 0.001). Multivariate analysis revealed that being single, having children, undergoing breast-conserving surgery, and elevated anxiety scores were independent predictors of poor sleep. Additionally, marital status, menopausal status, and treatment modality were significantly associated with anxiety and depression scores. Conclusions: One-third of Turkish breast cancer patients experience clinically relevant sleep disturbances, which are strongly linked to psychological distress, particularly anxiety. These findings underscore the importance of incorporating routine psychological screening into oncologic care and highlight the need for individualized psychosocial support strategies that aim to improve both emotional well-being and overall clinical outcomes.
1 January 2023 in Diagnostic and Interventional Endoscopy
Objective: Gynecological malignancies in women may be accompanied by metastatic/second primary gastrointestinal system cancer at the time of diagnosis. Recognition of gastrointestinal system involvement may change the treatment approach. Therefore, we aimed to detect and evaluate the gastr oscop y–col onosc opy findings performed in patients who had been diagnosed with gynecological malignancies in our clinic. Methods: Results of gastr oscop y–col onosc opies performed on patients with a diagnosis of gynecological malignancy in Manisa Celal Bayar University Hafsa Sultan Hospital Gastroenterology Department between June 2014 and September 2021 were reviewed retrospectively. Female patients who underwent gastr oscop y–col onosc opy due to iron deficiency anemia during the same period were selected as the control group. Results: The mean age of the patient population was 64.03, and the mean age of the control population was 62.1. All the patients were female. In our study group, there were 76 patients with gynecological malignancy. The control group included 79 patients who had iron deficiency anemia. As a result of gastros-copy, 10.56% of the study group was diagnosed with concomitant malignancy against 1.26% in the control group (P < .05). While the rate of cases diagnosed with lower gastrointestinal system malignancy after colonoscopy in the patient group was 9.21%, the same rate was found to be 1.26% in the control group (P < .05). Conclusion: We think that routine gastr oscop y–col onosc opic evaluation is necessary before treatment in women diagnosed with gynecological malignancy.