Effect of Duration of Pre-Procedure Fasting on Clinical Outcomes in Intensive Care Patients Undergoing Percutaneous Tracheostomy - Article abstract #950128

Aims: Spontaneous intracerebral hemorrhage (SIH) is a common cerebrovascular disease associated with high mortality and poor clinical outcomes. This study aimed to investigate the fundamental characteristics of patients with SIH, their treatment practices, and early results to provide a comprehensive overview. Methods: Patient records from 2017 to 2021 were reviewed following approval from the ethics committee of our hospital. Demographic data, surgical and medical treatments applied in the intensive care unit (ICU), and immediate clinical outcome data of patients meeting the study criteria were recorded and analyzed. Results: A total of 153 patients were included in this study. The mortality rate in SIH patients was identified as 53.59%. The mean age value of those who died was found to be higher. In these patients, "fainting" as the initial symptom was found to be more common, while "Focal Neurological Deficits" were less common. A lower median Glasgow Coma Scale (GCS) and higher Acute Physiology and Chronic Health Evaluation II (APACHE II) scores were also observed. It was noted that the fresh frozen plasma (FFP) usage rate was higher, whereas the usage rate of oral antihypertensives was lower in those who died. It was determined that 33.33 of patients, 33.33% were transferred to a service (neurology or neurosurgery), 11.76% received palliative care, and 1.31% received home care. Conclusion: The mortality rate of patients with SIH is extremely high, and treatment in intensive care should be conducted according to current guidelines. More comprehensive studies are needed to standardize the appropriate treatment approaches. Alongside suitable treatment strategies to reduce mortality, identifying and supporting surviving patients' long-term treatment and rehabilitation needs are of great significance.

During tympanoplasty surgery, the head and neck remain in the lateral position throughout the procedure. This situation may disrupt venous blood flow, comp

Background: Sepsis represents a severe clinical syndrome in which infection triggers a dysregulated host response, leading to life-threatening organ dysfunction and remaining among the leading causes of mortality worldwide. YouTube has emerged as a major source of health information, yet the quality of sepsis-related Turkish-language content has not been systematically examined. This study assessed the quality, reliability, and educational value of Turkish-language YouTube videos related to sepsis. Material and methods: A cross-sectional content analysis was performed on the first 100 Turkish-language videos retrieved on 1 August 2025, using the keywords “sepsis türkçe” and “türkçe sepsis”. Non-medical, duplicate, and short-form videos were excluded. Video characteristics, engagement metrics, sources, target audience, and coverage of core sepsis topics were recorded. Two reviewers independently assessed videos using the Global Quality Score (GQS), JAMA Benchmark Criteria, and Modified DISCERN Score (MDS). Comparative analyses examined differences before and after 2020, and correlations were calculated between video features and quality scores. Results: The mean video duration was 23.7 ± 37.1 minutes (range: 0.4–175.4). Overall quality was low-to-moderate (GQS 2.43 ± 1.37; JAMA 1.32 ± 1.20; MDS 2.42 ± 1.33). Hospitals (38%) and academic institutions (27%) were the main content producers, and 65% targeted the general public. Strong correlations were found between GQS and MDS (r = 0.71) and between JAMA and MDS (r = 0.80). Post-2020 videos were longer, better structured, and had higher quality scores, yet only 18% cited peer-reviewed sources or guidelines. Conclusion: Turkish-language YouTube videos on sepsis demonstrate considerable variability, yet their overall quality remains suboptimal. Although certain improvements have been observed since 2020, the majority of videos continue to lack transparency and evidence-based referencing. Collaboration between healthcare professionals and digital platforms, adherence to established benchmarks, and technological solutions are needed to strengthen online health communication.

Background: Coronary artery bypass grafting (CABG) is associated with a significant risk of postoperative major adverse event (MAE), largely driven by systemic inflammatory responses. Easily accessible inflammatory indices such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), and plateletcrit (PCT) have been proposed as potential predictors; however, the comparative performance and optimal timing of these indices remain unclear. Thus, this study aimed to evaluate the association between perioperative inflammatory indices measured at different time points and postoperative MAEs in patients undergoing elective on-pump CABG, and to compare the discriminatory performance of these indices. Methods: This single-center retrospective cohort study included 500 patients who underwent elective on-pump CABG between January 2022 and December 2023. Inflammatory indices (NLR, PLR, SII, and PCT) were calculated preoperatively and on postoperative days 0 (POD0), 1, and 3. The primary outcome was MAE, defined as mortality, stroke, sepsis, or acute kidney injury (AKI). Multivariable logistic regression and receiver operating characteristic curve analyses were performed to assess independent associations and discriminatory performance. Results: MAE occurred in 120 patients (24.0%) and were predominantly driven by AKI. Meanwhile, inflammatory indices measured on PODs0 and 1 showed limited discriminative ability. Conversely, NLR on POD3 was independently associated with MAE (odds ratio (OR): 1.16 per unit increase; 95% confidence interval (CI): 1.11–1.22; p < 0.001) and demonstrated the highest discriminatory performance (area under the curve (AUC): 0.733), followed by SII and PLR, whereas PCT showed poor performance. A cut-off value of NLR ≥10 on POD3 was associated with a significantly increased risk of MAE (OR: 3.98, 95% CI: 2.49–6.37; p < 0.001) and AKI (OR: 3.44, 95% CI: 2.09–5.66; p < 0.001). Conclusions: The prognostic value of inflammatory markers after CABG is time-dependent. NLR measured on POD3 showed the strongest and most consistent association with adverse outcomes and may serve as a practical tool for postoperative risk stratification, particularly for AKI. However, given the potential influence of reverse causality, these findings should be confirmed in prospective, multicenter studies.

The optimal management of enteral nutrition before tracheostomy in mechanically ventilated patients in the intensive care unit (ICU) remains uncertain, and