Zhuoneng Wu

Mr. Zhuoneng Wu


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 October 2025 in Bioengineering
Verified
Journal Article
Open access
PDF file
XZXiangliang Zhang
Xiangliang Zhang
WPWenhao Pan
Wenhao Pan
ZWZhuoneng Wu
Zhuoneng Wu
XLXiangzhi Liu
Xiangzhi Liu
YSYiping Sun
Yiping Sun
Tao LiuTao Liu
Tao Liu
Parkinson’s disease (PD) is one of the fastest-growing neurodegenerative disorders; its cardinal motor signs—tremor, bradykinesia, and rigidity—substantially impair quality of life. Conventional clinician-rated scales can be subjective and exhibit limited interrater reliability, underscoring the need for objective and reliable quantification. We present an integrated evaluation framework that leverages surface electromyography (sEMG) with multimodal sensing. For representation learning, we combine time–frequency descriptors with Mini-ROCKET features. Grading is performed by an sEMG-based Unified Parkinson’s Disease Rating Scale (UPDRS) model (LDA-SV) that produces per-segment probabilities for ordinal scores (0–3) and aggregates them via soft voting to assign item-level ratings. Participants completed a standardized protocol spanning gait, seated rest, and upper-limb tasks (forearm pronation–supination, finger-to-nose, fist clench, and thumb–index pinch). Using the aforementioned dataset, we report task-wise performance with 95% confidence intervals and compare the proposed model against CNN, LSTM, and InceptionTime using McNemar tests and log-odds ratios. The results indicate that the proposed model outperforms the three baseline models overall. These findings demonstrate the effectiveness and feasibility of the proposed approach, suggesting a viable pathway for the objective quantification of PD motor symptoms and facilitating broader clinical adoption of sEMG in diagnosis and treatment.