Robot-based rehabilitation emerges as a promise to enhance mobility and improve the rehabilitation outcomes in children with cerebral palsy. The study aimed to evaluate the preliminary effects of a robot-based therapy program with Atlas-2030 on spatiotemporal gait parameters, pelvis kinematics, gross-motor function, quality of life, and joint range-of-motion in children with cerebral palsy receiving care at a specialized rehabilitation center. This is a single-arm, institution-based, quantitative, longitudinal, pilot study with repeated measures. Sixteen sessions of a robot-based therapy program with the Atlas-2030 wearable exoskeleton were applied to all the children from APAC-IAP in Mexico City with cerebral palsy. Pre-intervention, after eight and sixteen sessions, the GMFM-66, the CP QoL-Child, and gait analysis were performed. The results suggest that an Atlas-2030 robot-based therapy program combined with therapeutic stimulation exhibited better scores on the modified Ashworth scale: hip flexors and extensors: 2.0(1.0), knee flexors and extensors: 2.0(2.9), p > 0.0167, and experience enhanced range of motion in hip flexion: 122.5(5) deg, and extension: 11(5) deg and knee extension: 0(5) deg, p < 0.0167, pelvis rotation approached zero on both sides (left: −1.99(14.04, right: 2.22(13.43), p > 0.0167) reducing the difference in laterality, inducing physiological muscle activation patterns, and higher scores in quality of life regarding well-being and acceptance: 17(1.0) and emotional well-being and self-esteem: 14.5 (1.0), p > 0.0167. The limitations of this study include the following: recruitment from a single specialty care center, the absence of a control group, and the adjusted significance level of p < 0.0167, which may lead to false negatives.