Francisco Manuel García-Blázquez

Dr. Francisco Manuel García-Blázquez


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 April 2023 in Journal of Fungi
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Journal Article
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JRJulia Villar Rodríguez
Julia Villar Rodríguez
Ana María PicoAna María Pico
Ana María Pico
FGFrancisco Manuel García-Blázquez
Francisco Manuel García-Blázquez
JMJuan Francisco Moran-Cortes
Juan Francisco Moran-Cortes
Raquel MayordomoRaquel Mayordomo
Raquel Mayordomo
Onychomycosis is usually diagnosed symptomatically due to the very clear signs caused by the fungus on the nail surface and structure, although the growth of the infecting agent must also be verified by culture in an enriched medium. This procedure is normally lengthy (four weeks), and samples can be contaminated, delaying the prescription of appropriate and effective treatment. Only one previous study has addressed the possibility of using thermography as a diagnostic method for onychomycosis in older people (31–70 years). The present study confirms this use but in individuals aged 18–31 years with incipient mycosis and no pathological signs. Using an FLIR E60 BX camera in a study with 214 samples, we found that men had more onychomycosis than women. We observed a relation between the presence of infection and nail temperature, with a higher temperature in yeast infections (+1 °C) and a lower temperature in dermatophyte infections (−2 °C). A higher temperature by almost 1 °C was also observed in older participants. Thermography can be viewed as a new diagnostic method in asymptomatic or incipient onychomycosis, providing the thermographic camera is sufficiently sensitive and the appropriate procedure is followed, although fungal culture is always necessary to confirm recovery after treatment.

24 February 2023 in Applied Sciences
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Journal Article
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DHDaniel Jonathan Navas Harrison
Daniel Jonathan Navas Harrison
Ana María PicoAna María Pico
Ana María Pico
FGFrancisco Manuel García-Blázquez
Francisco Manuel García-Blázquez
Raquel MayordomoRaquel Mayordomo
Raquel Mayordomo
Anthropometry and kinanthropometry are sciences that measure variations in the physical dimensions and composition of the human body. There are studies that analyze these parameters individually, but we believe that it is much better to analyze them globally. We realized a multivariate analysis, to determine which variables could explain the profiles of the subjects depending on sex, lifestyle, and type of sports modality. We analyzed 25 variables in a population of 574 people aged between 18 and 42 years. A multivariate statistical analysis was performed using exploratory factor analysis, and then we obtained five differentiating variables: fat mass, muscle mass, bone mass, skinfolds, and robustness. We classified the population into sedentary lifestyle, amateur athletes with predominance of the upper and lower train, and amateur athletes with predominance mainly of the lower train, in an attempt to analyze the existence of statistical significance between them. Amateur athletes with a predominance of the upper and lower train have a higher Body Mass Index and a lower Relative Index of the Lower Limbs, in addition to greater muscle mass and robustness than those athletes with a predominance mainly of the lower train. The sedentary control group presented higher values in terms of skinfolds and fat mass. This work could help people to choose the best sport according to their morphotype, and also could be used to plan sports training to potentiate different body regions, injury recovery, selection of talented athletes, etc.

19 February 2025 in Diagnostics
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MCMaria de la Luz Canal-Macías
Maria de la Luz Canal-Macías
VVVicente Vera-Rodríguez
Vicente Vera-Rodríguez
OLOlga Leal-Hernández
Olga Leal-Hernández
JGJulián Fernando Calderón García
Julián Fernando Calderón García
RRRaúl P. Roncero-Martín
Raúl P. Roncero-Martín
MPMaría Pedrera-Canal
María Pedrera-Canal
Background and Objectives: Analysing the characteristics of the mandibular bone through panoramic radiographs could be useful as a prescreening tool for detecting individuals with osteoporosis. The aims of this study were to evaluate the possible associations between the mandibular cortical index (MCI) and bone mineral density (BMD) in various bone regions, to investigate whether BMD better identifies moderate–severe mandibular erosion or severe mandibular erosion, and to establish BMD cut-off points to identify individuals with moderate or severe mandibular cortical erosion. Methods: This study analysed 179 Spanish Caucasian women between September 2021 and June 2024. Bone measurements, including amplitude-dependent speed of sound (Ad-SOS), the ultrasound bone profiler index (UBPI), and the bone transmission time (BTT), were obtained via dual energy X-ray absorptiometry (DXA) for the femoral neck, lumbar spine, and trochanter and quantitative bone ultrasound (QUS) for the phalanx. The MCI was calculated via the Klemetti index from panoramic radiographs. Results: According to the Klemetti index classification, lower QUS measurements in the phalanx and DXA measurements in the femoral neck, trochanter, and lumbar spine were found in women with poorer mandibular cortical bone quality. Our results revealed that, compared with moderate cortical erosion, all the BMD measures had better AUCs when identifying severe cortical erosion. Moreover, femoral neck BMD had the largest area under the curve (AUC = 0.719) for detecting severe mandibular cortical erosion, suggesting a cut-off of <0.703 gr/cm2. Finally, predictor analysis of osteoporosis revealed that moderate and severe mandibular cortical erosion, compared with an uninjured mandibular cortical area, was independently associated with a diagnosis of osteoporosis. Conclusions: In conclusion, MCI was associated with BMD measurements assessed by QUS and DXA in various bone regions. Our results suggest that the Klemetti index could be used as a predictor of osteoporosis and fracture risk.

7 October 2025 in Healthcare
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Journal Article
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VVVicente Vera-Rodríguez
Vicente Vera-Rodríguez
MPMaría Pedrera-Canal
María Pedrera-Canal
OLOlga Leal-Hernández
Olga Leal-Hernández
JFJuan Fabregat-Fernández
Juan Fabregat-Fernández
MCMaria de la Luz Canal-Macías
Maria de la Luz Canal-Macías
RRRaúl P. Roncero-Martín
Raúl P. Roncero-Martín
Background/Objectives: Thyroid hormone deficiency may impair bone metabolism, but its mandibular impact remains uncertain. We aimed to compare the prevalence of altered Mandibular Cortical Index (MCI; C2–C3) and Panoramic Mandibular Index (PMI) on digital panoramic radiographs in adult women with primary hypothyroidism versus euthyroid controls, considering age and key clinical covariates. To our knowledge, this is the first study out of Spain addressing this question. Methods: This is a cross-sectional study (September 2021–June 2024) of 179 white women recruited at a university clinic. Cases were on L-thyroxine for ≥6 months, with TSH > 4.5 mIU/L and normal FT4; controls were euthyroid and untreated. Demographics, reproductive history, and BMI were recorded. Panoramic radiographs (Ratograph EVO 3D; 72 kV, 6 mA, 14.4 s) were analysed; MCI was graded (Klemetti C1–C3) distal to the mental foramen; PMI and mandibular cortical width (MCW) were measured bilaterally. Results: Women with hypothyroidism showed higher BMI and a greater number of years since menopause; age was slightly higher, but the difference was not significant. MCI distribution did not differ between groups (C3 and C2–C3, both p > 0.45). PMI (left/right) was similar (p = 0.253/0.160). Left MCW was higher in hypothyroidism in a crude analysis (4.86 ± 0.98 vs. 4.46 ± 0.94 mm; p = 0.039), but lost significance after age adjustment (adjusted p = 0.191); right MCW showed no differences. Total tooth loss tended to be higher (p = 0.055) without conclusive evidence. Conclusions: In this cohort, primary hypothyroidism was not associated with a differential mandibular cortical pattern by MCI or PMI; the crude MCW difference was explained by age. These Spain-based data refine heterogeneous prior findings and indicate that, in women treated for hypothyroidism, mandibular cortical metrics largely resemble those of their euthyroid peers. Longitudinal and multicentre studies are warranted to clarify trajectories and enhance generalisability.