Despite regulatory advances, there continues to be a high accident rate on construction sites, especially on road projects, mainly due to the lack of organization of safety information. Although there is research demonstrating the benefits of the BIM methodology for improving occupational safety, its scope is still limited. This study addresses the integration of occupational health and safety in road projects using the BIM methodology, in line with ISO 19650-1, proposing a standardization framework based on ISO 7817-1:2024. The concept of Level of Information for Safety and Health (LOINSH) is introduced, structured into four categories (100, 200, 300, and 350), which allows risks to be managed progressively throughout the project’s life cycle. The framework defines graphical and alphanumeric requirements for BIM objects, establishing sets of parameters recognized by the open IFC format to ensure interoperability and traceability. It also proposes a system for assessing risks associated with activities and disciplines, facilitating preventive decisions from the design stage onwards. The results indicate that this standardization improves communication and collaboration between agents, reduces workplace accidents, and can be applied to other types of construction works.