Objectives. The NUTRIC (nutrition risk in the critically ill) score and the modified NUTRIC score are two scoring systems that show the nutritional risk status and severity of acute disease of patients. The only difference between them is the examination of interleukin‐6 (IL‐6) level. The aim of this study was to investigate whether or not the NUTRIC score is superior to the mNUTRIC score in the prediction of mortality of patients with COVID‐19 followed up in the Intensive Care Unit (ICU). Material and Method. This retrospective study included 322 patients followed up in ICU with a diagnosis of COVID‐19. A record was made of demographic data, laboratory values, clinical results, and mortality status. All the data of the patients were compared between high and low variations of the NUTRIC score and the mNUTRIC score. Results. A high NUTRIC score was determined in 62 patients and a high mNUTRIC score in 86 patients. The need for invasive mechanical ventilation, the use of vasopressors in ICU, the development of acute kidney injury, and mortality rates were statistically significantly higher in the patients with high NUTRIC and high mNUTRIC scores than in those with low scores (p = 0.0001 for all). The AUC values were 0.791 for high NUTRIC score and 0.786 for high mNUTRIC score (p = 0.0001 for both). No statistically significant difference was determined between the two scoring systems. Conclusion. Although the NUTRIC score was seen to be superior to the mNUTRIC score, no statistically significant difference was determined. Therefore, when IL‐6 cannot be examined, the mNUTRIC score can be considered safe and effective for the prediction of mortality in COVID‐19 patients.

Nucleated Red Blood Cells for Predicting Mortality in Intensive Care Unit Patients with Sepsis - Article abstract #950504

Aim: The Delta Neutrophil Index (DNI) shows the ratio of immature granulocytes in the circulation and increases in conditions of infection and inflammation. The aim of this study was to investigate the suitability of using DNI as a prognostic marker of mortality in COVID-19 patients in the Intensive Care Unit (ICU). Material and Method: This retrospective study included 316 patients followed up in the ICU with a diagnosis of COVID-19. A record was made for each patient of demographic data, laboratory values, clinical results and mortality status. All the data of the patients were evaluated and compared between the two groups of surviving and non-surviving patients. Results: Mortality developed in 181 (57.27%) patients. The Glasgow Coma Scale score was lower and the APACHE II and SOFA scores were higher in the mortality group than in the surviving group (p<0.001 for all). The creatinine, procalcitonin, white blood cell, neutrophil count, neutrophil-lymphocyte ratio, lactate, interleukin -6 and C-reactive protein values were statistically significantly higher in the mortality group. In the comparison of DNI between the groups, a statistically significant difference was only determined on day 3 (p=0.026). For the DNI examined on day 3, the AUC value was 0.574 and the cutoff value was 1.35% for the prediction of mortality. Conclusion: DNI, which is low cost and simple to use, can be considered safe for use in the prediction of mortality of ICU patients diagnosed with COVID-19. The monitoring of increasing or decreasing trends by keeping regular records can be considered important for the clinical course.

Aims:This study aimed to investigate the effectiveness of immature granulocyte count and the percentage of immature granulocytes in predicting mortality in patients aged 80 years and older (octogenarians) in intensive care units. Methods: This retrospective study included 333 patients aged 80 years and older who were followed up in the intensive care unit. Demographic data, laboratory values, clinical outcomes, and mortality status were recorded. The data were evaluated in two groups: survivors and deaths. Differences between the groups were statistically analyzed and compared. Results: While the Glasgow Coma Scale(GCS) was lower in the mortality group, the Acute Physiology and Chronic Health Evaluation II(APACHE II) and Sequential Organ Function Assessment(SOFA) scores were higher than in the survivors (p<0.001 for all). C reactive protein (CRP), neutrophil-to-lymphocyte ratio, and lactate values were significant markers for mortality prediction. No significant difference was found for immature granulocyte count and percentage when the groups were compared. APACHE II and SOFA scores had the highest discriminatory power in predicting mortality, with the area under the curve= 0.74. Conclusion: In octogenarian patients followed up in the intensive care unit, we found that the number and percentage of immature granulocytes was not an effective biomarker for predicting mortality despite its cheap and easy use. In the future, more comprehensive studies may show the importance of immature granulocytes.

Akut Böbrek Hasarı Tanımı ve Patofizyolojisi Hayriye CANKAR DAL Akut Böbrek Hasarı Biyobelirteçleri Esra YAKIŞIK ÇAKIR Akut Böbrek Hasarında Renal Koruma Ayşe Müge KARCIOĞLU Işıl ÖZKOÇAK TURAN Akut Böbrek Hasarının Yönetimi ve Renal Replasman Tedavisi Dışındaki Tedavi Yöntemleri Mehmet Eren YÜKSEL Ahmet Gökhan AKDAĞ Sürekli Renal Replasman Tedavisi Tarihçesi Derya GÖKÇINAR Fizyolojik Prensipler ve Terminoloji Büşra TEZCAN Cihazın Yapısı ve Bileşenleri Sema TURAN Çilem BAYINDIR DİCLE Sürekli Renal Replasman Tedavisinde Kullanılan Membran ve Filtreler Tülay TUNÇER PEKER Sevil BALTACI ÖZEN Sürekli Renal Replasman Tedavisinde Kullanılan Tampon Solüsyonlar Belgin AKAN Kurulum Behiye Deniz KOSOVALI Sürekli Renal Replasman Tedavisinde Gösterge ve Alarmlar Serdar YAMANYAR Sürekli Renal Replasman Tedavisinde Vasküler Erişim Yolları Berkay KÜÇÜK Belgin AKAN Sürekli Renal Replasman Tedavisi Endikasyonları ve Zamanlama Mete ERDEMİR Sercan YILMAZ Levent YAMANEL Tedavi Modalitesi Seçimi Dilek ÖZTÜRK KAZANCI Müçteba CAN Dozun Belirlenmesi ve Reçeteleme Hasan DİRİK Demet BÖLÜKBAŞI Rejyonel Sitrat Antikoagülasyonu Mehmet Eren YÜKSEL Seval İZDEŞ Sitrat Dışı Antikoagülasyon Baha Burak KONAK Seval İZDEŞ Hasta Monitörizasyonu ve Sonlandırma Kararı Mahmut YILMAZ Gürhan TAŞKIN Sürekli Renal Replasman Tedavisinin Komplikasyonları Şerife GÖKBULUT BEKTAŞ Ahmet Bilal KANDEMİR Sepsis ve SRRT Dilek ÖZTÜRK KAZANCI Sema SARI Sürekli Renal Replasman Tedavisinde Sıvı Yönetimi Cihangir DOĞU Beslenme ve Sürekli Renal Replasman Tedavisi Deniz ERDEM ECMO Uygulanan Hastada SRRT Sema TURAN İbrahim MUNGAN İlaç Uygulamaları ve SRRT Tülay TUNÇER PEKER Sürekli Renal Replasman Tedavisinin Ekstrarenal Endikasyonları Baha Burak KONAK Seval İZDEŞ Çoklu Organ Destek Tedavisi Derya GÖKÇINAR