Objectives. The NUTRIC (nutrition risk in the critically ill) score and the modified NUTRIC score are two scoring systems that show the nutritional risk status and severity of acute disease of patients. The only difference between them is the examination of interleukin‐6 (IL‐6) level. The aim of this study was to investigate whether or not the NUTRIC score is superior to the mNUTRIC score in the prediction of mortality of patients with COVID‐19 followed up in the Intensive Care Unit (ICU). Material and Method. This retrospective study included 322 patients followed up in ICU with a diagnosis of COVID‐19. A record was made of demographic data, laboratory values, clinical results, and mortality status. All the data of the patients were compared between high and low variations of the NUTRIC score and the mNUTRIC score. Results. A high NUTRIC score was determined in 62 patients and a high mNUTRIC score in 86 patients. The need for invasive mechanical ventilation, the use of vasopressors in ICU, the development of acute kidney injury, and mortality rates were statistically significantly higher in the patients with high NUTRIC and high mNUTRIC scores than in those with low scores (p = 0.0001 for all). The AUC values were 0.791 for high NUTRIC score and 0.786 for high mNUTRIC score (p = 0.0001 for both). No statistically significant difference was determined between the two scoring systems. Conclusion. Although the NUTRIC score was seen to be superior to the mNUTRIC score, no statistically significant difference was determined. Therefore, when IL‐6 cannot be examined, the mNUTRIC score can be considered safe and effective for the prediction of mortality in COVID‐19 patients.

Amaç: Pandeminin ilk dört aylık döneminde koronavirüs hastalığı-2019 (COVİD-19) şüphesiyle, COVİD-19 YBÜ’lerine kabul edilen hastalar tanılarına ve dönemlere göre karşılaştırıldı. Gereç ve Yöntem: Tek merkezde aynı algoritma ile COVİD-19 YBÜ’ye kabul edilen 1,430 hasta verisi retrospektif olarak kaydedildi. Hastalar polimeraz zincirleme reaksiyonu sonucu ile radyolojik ve klinik bulgulara göre COVİD-19 ve non-COVİD-19 hastalar olarak sınıflandırıldılar. Ayrıca COVİD-19 hastaları mortalite ve sağkalım açısından da karşılaştırıldı. Bunun yanında, pandeminin başlangıcı ve normalleşme döneminde COVİD-19 YBÜ’lerine kabul edilen hastaların verileri değerlendirildi. Bulgular: Çalışmaya alınan 1,430 hastanın 630’u COVİD-19, 800’ü non-COVİD-19 gruptaydı. Yaş ortalamalarında anlamlı bir farklılık bulunurken, cinsiyetler arasında bir farklılık yoktu (p=0,001, p=0,262). COVİD-19 ölen grubun yaş ortalaması yaşayan gruptan daha yüksekti (p

AMAÇ: Ulusal ve uluslararası yoğun bakım ünitelerindeki (YBÜ) mortalite oranları en güvenilir performans göstergesidir. Ancak, Ulusal açıdan geniş kapsamlı mortalite verilerine sahip değiliz. Çalışmamızda, YBÜ’mize yatan hastaların mortalite oranları ve risk faktörlerinin belirlenmesi amaçlanmıştır. GEREÇ VE YÖNTEMLER: 1 Ağustos 2017 ile 31 Aralık 2018 tarihleri arasında 18 yaşından büyük Anestezi ve Reanimasyon YBÜ’mize yatan tüm hastalar çalışmamıza dahil edildi. Hastaların yatış anında yaşları, cinsiyetleri, yatış nedenleri (organ sistemleri, travma, zehirlenme, enfeksiyon gibi), kabul edilen servis (acil veya diğer yataklı servisler), komorbid hastalık, yatış süreleri ve mortaliteleri kayıt edildi. BULGULAR: Çalışmamıza 757 hasta çalışmaya dahil edildi. Toplam mortalite oranı %34,7 olarak bulundu. En yüksek yatış oranı nörolojik sistem nedenli (%27,6) ve en yüksek mortalite oranı (%47,8) kardiyovasküler nedenli olarak bulundu. Erkek cinsiyette mortalite oranı kadın cinsiyetten anlamlı düşük (%45,2 v.s. %60,9) bulundu (p<0,001). Mortalite olan hastalarda ortalama yaş (70,1±16,8 yıl) ve komorbid hastalık oranı (%95,1) yaşayanlarda ortalama yaş (66,5±14,9 yıl) ve komorbid hastalık (%83,3) anlamlı yüksek bulundu (sırasıyla, p=0,023, p=0,035). SONUÇ: Çeşitli hastalık gruplarını takip eden YBÜ’mizde mortalite oranları diğer ünitelerin verileri ile benzer bulunmuştur. Her ünitenin kendi mortalite verilerini değerlendirmesi hastane performansı ve hasta bakım kalitesini artırmak için yapması gerekmektedir.

Aim: The Delta Neutrophil Index (DNI) shows the ratio of immature granulocytes in the circulation and increases in conditions of infection and inflammation. The aim of this study was to investigate the suitability of using DNI as a prognostic marker of mortality in COVID-19 patients in the Intensive Care Unit (ICU). Material and Method: This retrospective study included 316 patients followed up in the ICU with a diagnosis of COVID-19. A record was made for each patient of demographic data, laboratory values, clinical results and mortality status. All the data of the patients were evaluated and compared between the two groups of surviving and non-surviving patients. Results: Mortality developed in 181 (57.27%) patients. The Glasgow Coma Scale score was lower and the APACHE II and SOFA scores were higher in the mortality group than in the surviving group (p<0.001 for all). The creatinine, procalcitonin, white blood cell, neutrophil count, neutrophil-lymphocyte ratio, lactate, interleukin -6 and C-reactive protein values were statistically significantly higher in the mortality group. In the comparison of DNI between the groups, a statistically significant difference was only determined on day 3 (p=0.026). For the DNI examined on day 3, the AUC value was 0.574 and the cutoff value was 1.35% for the prediction of mortality. Conclusion: DNI, which is low cost and simple to use, can be considered safe for use in the prediction of mortality of ICU patients diagnosed with COVID-19. The monitoring of increasing or decreasing trends by keeping regular records can be considered important for the clinical course.

Nucleated Red Blood Cells for Predicting Mortality in Intensive Care Unit Patients with Sepsis - Article abstract #950504

Background/Objectives: Adult modified Renal Angina Index (mRAI) formulations predict acute kidney injury, but their association with major adverse kidney events at 90 days (MAKE90) remains unclear. We examined the association in critically ill adults without established chronic kidney disease (CKD). Methods: This retrospective cohort included 250 adults admitted to a tertiary intensive care unit (ICU) between December 2023 and April 2025. mRAI was calculated from data available at ICU admission. MAKE90 was defined as death, renal replacement therapy, or persistent renal dysfunction within 90 days. We used logistic regression, receiver operating characteristic analysis, and nested-model comparisons. Results: Admission mRAI was higher in patients with MAKE90 than in those without MAKE90 (median 10 [IQR 5–20] vs. 3 [IQR 1–6]; p < 0.001). After adjustment for SOFA score and sepsis, mRAI remained associated with MAKE90 (adjusted OR per point from the linear model, 1.073; 95% CI, 1.032–1.116). Spline analysis demonstrated a significant nonlinear association (p = 0.004), indicating that the per-point OR should be interpreted as a summary estimate rather than a constant effect across the score range. The AUC of mRAI was 0.752 (95% CI, 0.691–0.814), higher than that of admission AKI stage (0.653) and not significantly different from APACHE II (0.702) or SOFA (0.718). Adding mRAI to SOFA and sepsis raised the AUC from 0.735 to 0.782. Conclusions: In critically ill adults without established CKD, higher admission mRAI remained associated with MAKE90 after adjustment for SOFA score and sepsis and showed moderate discrimination. External validation in larger, independent cohorts is needed to confirm these findings.