This study explores the pedagogical impact of a student-led teaching strategy in veterinary education, centered on the implementation of a monitored question-and-answer (Q&A) game integrated with multimedia content. Conducted in a classroom setting, the intervention encouraged students to actively formulate and pose questions to their peers—questions that could potentially appear on future assessments. The sessions were recorded and transformed into multimedia resources, enabling content review beyond the classroom. Results indicate a high student participation during practical activities (89.33%), as well as enhanced engagement with course material outside scheduled sessions. Students’ perceptions were collected in a survey (Cronbach’s alpha 0.920), revealing that more than sixty percent of answers fostered collaborative learning and anatomy assessments preparation. Moreover, fifty percent of students affirmed that the activity enhanced their participation and motivation and stimulated peer-to-peer interaction. These results could suggest that gamified student-led questioning combined with digital content creation can effectively support active learning and deeper understanding in veterinary anatomy education.

(1) Background: Salmonella are zoonotic pathogens, and rising antimicrobial resistance (AMR) amplifies their public health impact. Asymptomatic horses can act as reservoirs, contributing to environmental contamination and interspecies transmission. This study aimed to estimate the prevalence of Salmonella and characterize AMR patterns in healthy horses from eastern Spain. (2) Methods: Faecal samples from 95 asymptomatic horses were collected once daily over five consecutive days (475 samples in total) and processed under for Salmonella detection. Epidemiological information was obtained through owner questionnaires, and associations with Salmonella shedding were analyzed using generalized linear models. Antimicrobial susceptibility was assessed by minimum inhibitory concentration assays following the European Committee on Antimicrobial Susceptibility Testing (EUCAST) criteria. (3) Results:Salmonella was detected in 25.3% of horses (24/95), with S. Enteritidis, S. Johannesburg, and S. Virchow as the most frequent serotypes. A significant association was observed between proximity of manure storage and bacterial detection (p < 0.001). Among 24 isolates of Salmonella, 88.9% were resistant to at least one antimicrobial, and 50% exhibited multidrug resistance. The highest resistance rates were against sulfamethoxazole and gentamicin, followed by ciprofloxacin and tigecycline. (4) Conclusions: Healthy horses can act as silent carriers of multidrug-resistant Salmonella, highlighting the need for surveillance, strengthened biosecurity, and prudent antimicrobial use within a One Health framework.