Kunlun Huang

Kunlun Huang


Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 May 2021 in Nutrients
Verified
Journal Article
Open access
PDF file
RGRuixuan Geng
Ruixuan Geng
SKSeong-Gook Kang
Seong-Gook Kang
KHKunlun Huang
Kunlun Huang
Tao TongTao Tong
Tao Tong
Skin photoaging is mainly induced by ultraviolet (UV) irradiation and its manifestations include dry skin, coarse wrinkle, irregular pigmentation, and loss of skin elasticity. Dietary supplementation of nutraceuticals with therapeutic and preventive effects against skin photoaging has recently received increasing attention. This article aims to review the research progress in the cellular and molecular mechanisms of UV-induced skin photoaging. Subsequently, the beneficial effects of dietary components on skin photoaging are discussed. The photoaging process and the underlying mechanisms are complex. Matrix metalloproteinases, transforming growth factors, skin adipose tissue, inflammation, oxidative stress, nuclear and mitochondrial DNA, telomeres, microRNA, advanced glycation end products, the hypothalamic–pituitary–adrenal axis, and transient receptor potential cation channel V are key regulators that drive the photoaging-associated changes in skin. Meanwhile, mounting evidence from animal models and clinical trials suggests that various food-derived components attenuate the development and symptoms of skin photoaging. The major mechanisms of these dietary components to alleviate skin photoaging include the maintenance of skin moisture and extracellular matrix content, regulation of specific signaling pathways involved in the synthesis and degradation of the extracellular matrix, and antioxidant capacity. Taken together, the ingestion of food-derived functional components could be an attractive strategy to prevent skin photoaging damage.

11 April 2022 in Food Chemistry
Verified
Journal Article
Closed access
GSGuangchun Song
Guangchun Song
JZJunjie Zhang
Junjie Zhang
HHHuixian Huang
Huixian Huang
XWXin Wang
Xin Wang
XHXiaoyun He
Xiaoyun He
Nan ChengNan Cheng
Nan Cheng

19 December 2017 in Analytical Chemistry
Verified
Journal Article
Closed access
YXYuancong Xu
Yuancong Xu
YWYujun Wei
Yujun Wei
NCNan Cheng
Nan Cheng
KHKunlun Huang
Kunlun Huang
WWWeiran Wang
Weiran Wang
YLYunbo Luo
Yunbo Luo

1 January 2022 in Journal of Controlled Release
Verified
Journal Article
Closed access
KCKeren Chen
Keren Chen
YZYangzi Zhang
Yangzi Zhang
LZLongjiao Zhu
Longjiao Zhu
HCHuashuo Chu
Huashuo Chu
XSXiangli Shao
Xiangli Shao
WXWentao Xu
Wentao Xu

18 September 2021 in Catalysts
Verified
Journal Article
Open access
PDF file
GSGuangchun Song
Guangchun Song
Nan ChengNan Cheng
Nan Cheng
JZJunjie Zhang
Junjie Zhang
HHHuixian Huang
Huixian Huang
YYYanfang Yuan
Yanfang Yuan
KHKunlun Huang
Kunlun Huang
Nanoscale cerium oxide has excellent catalytic performance due to its unique surface properties and has very important applications in various fields. In this paper, the synthesis methods, catalytic mechanism and activity regulation of nanoscale cerium oxide in recent years are reviewed. Secondly, the application of cerium oxide in the detection of organic and inorganic molecules is summarized, and its latest progress and applications in antibacterial, antioxidant and anticancer are discussed. Finally, the future development prospect of nanoscale cerium oxide is summarized and prospected.

Verified
Journal Article
Open access
PDF file
TMTianyi Ma
Tianyi Ma
KHKunlun Huang
Kunlun Huang
Nan ChengNan Cheng
Nan Cheng
Pathogen detection and control have long presented formidable challenges in the domains of medicine and public health. This review paper underscores the potential of nanozymes as emerging bio-mimetic enzymes that hold promise in effectively tackling these challenges. The key features and advantages of nanozymes are introduced, encompassing their comparable catalytic activity to natural enzymes, enhanced stability and reliability, cost effectiveness, and straightforward preparation methods. Subsequently, the paper delves into the detailed utilization of nanozymes for pathogen detection. This includes their application as biosensors, facilitating rapid and sensitive identification of diverse pathogens, including bacteria, viruses, and plasmodium. Furthermore, the paper explores strategies employing nanozymes for pathogen control, such as the regulation of reactive oxygen species (ROS), HOBr/Cl regulation, and clearance of extracellular DNA to impede pathogen growth and transmission. The review underscores the vast potential of nanozymes in pathogen detection and control through numerous specific examples and case studies. The authors highlight the efficiency, rapidity, and specificity of pathogen detection achieved with nanozymes, employing various strategies. They also demonstrate the feasibility of nanozymes in hindering pathogen growth and transmission. These innovative approaches employing nanozymes are projected to provide novel options for early disease diagnoses, treatment, and prevention. Through a comprehensive discourse on the characteristics and advantages of nanozymes, as well as diverse application approaches, this paper serves as a crucial reference and guide for further research and development in nanozyme technology. The expectation is that such advancements will significantly contribute to enhancing disease control measures and improving public health outcomes.