Skin-lesion recognition from clinical photographs is clinically valuable yet computationally challenging due to large intra-class variation, subtle inter-class boundaries, class imbalance, and heterogeneous acquisition conditions. To address these constraints under realistic compute budgets, we investigate Inception-family convolutional baselines and propose GISLC—a Gated-Inception model that augments a GoogLeNet/Inception-V1 backbone with a lightweight, spatial gating head inspired by ConvLSTM. Unlike static fusion (concatenation/summation) of multi-branch features, the proposed gated head performs per-location, learnable regulation of feature flow across branches, prioritizing diagnostically salient patterns while suppressing redundant activations. Experiments were conducted on the clinical-images subset of the Multimodal Augmented Skin Lesion Dataset (MASLD), an augmented derivative of HAM10000, using stratified train/validation/test splits, clinically motivated augmentation, and class-weighted optimization to mitigate skewed label frequencies. A controlled ablation study evaluates backbone choices and optimization settings and isolates the contribution of gated fusion relative to standard Inception heads. Across runs, the gated fusion strategy improves discriminative performance while remaining parameter-efficient, supporting the view that spatially adaptive regulation can enhance robustness on non-dermatoscopic clinical imagery. We further outline practical steps for calibration analysis and compression-aware deployment in clinical and edge settings.

Dysregulation of lung tissue collagen level plays a vital role in understanding how lung diseases progress. However, traditional scoring methods rely on manual histopathological examination introducing subjectivity and inconsistency into the assessment process. These methods are further hampered by inter-observer variability, lack of quantification, and their time-consuming nature. To mitigate these drawbacks, we propose a machine learning-driven framework for automated scoring of lung collagen content. Our study begins with the collection of a lung slide image dataset from adult female mice using second harmonic generation (SHG) microscopy. In our proposed approach, first, we manually extracted features based on the 46 statistical parameters of fibrillar collagen. Subsequently, we pre-processed the images and utilized a pre-trained VGG16 model to uncover hidden features from pre-processed images. We then combined both image and statistical features to train various machine learning and deep neural network models for classification tasks. We employed advanced unsupervised techniques like K-means, principal component analysis (PCA), t-distributed stochastic neighbour embedding (t-SNE), and uniform manifold approximation and projection (UMAP) to conduct thorough image analysis for lung collagen content. Also, the evaluation of the trained models using the collagen data includes both binary and multi-label classification to predict lung cancer in a urethane-induced mouse model. Experimental validation of our proposed approach demonstrates promising results. We obtained an average accuracy of 83% and an area under the receiver operating characteristic curve (ROC AUC) values of 0.96 through the use of a support vector machine (SVM) model for binary categorization tasks. For multi-label classification tasks, to quantify the structural alteration of collagen, we attained an average accuracy of 73% and ROC AUC values of 1.0, 0.38, 0.95, and 0.86 for control, baseline, treatment_1, and treatment_2 groups, respectively. Our findings provide significant potential for enhancing diagnostic accuracy, understanding disease mechanisms, and improving clinical practice using machine learning and deep learning models.

Unmanned Aerial Systems (UASs) are playing an increasingly critical role in both civilian and defense applications. However, their heavy reliance on unencrypted Global Navigation Satellite System (GNSS) signals, particularly GPS, makes them highly susceptible to signal spoofing attacks, posing severe operational and safety threats. This paper introduces a comprehensive, AI-driven multi-layer sensor framework that simultaneously enables real-time spoofing detection and secure command-and-control (C2) communication in lightweight UAS platforms. The proposed system enhances telemetry reliability through a refined preprocessing pipeline that includes a novel GPS Drift Index (GDI), robust statistical normalization, cluster-constrained oversampling, Kalman-based noise reduction, and quaternion filtering. These sensing layers improve anomaly separability under adversarial signal manipulation. On this enhanced feature space, a differentiable architecture search (DARTS) approach dynamically generates lightweight neural network architectures optimized for fast, onboard spoofing detection. For secure command and control, the framework integrates a low-latency cryptographic layer utilizing PRESENT-128 encryption and CMAC authentication, achieving confidentiality and integrity with only 1.79 ms latency and a 0.51 mJ energy cost. Extensive experimental evaluations demonstrate the framework’s outstanding detection accuracy (99.99%), near-perfect F1-score (0.999), and AUC (0.9999), validating its suitability for deployment in real-world, resource-constrained UAS environments. This research advances the field of AI-enabled sensor systems by offering a robust, scalable, and secure navigation framework for countering GPS spoofing in autonomous aerial vehicles.

UAV-based remote sensing systems are increasingly deployed in smart surveillance, disaster response, environmental monitoring, and critical infrastructure inspection. In these applications, aerial sensing platforms must transmit telemetry, control commands, and observation data securely and reliably under strict latency, energy, and computational constraints. However, existing security approaches often fail to jointly provide lightweight payload confidentiality, quantum-resilient key establishment, and adaptive communication protection suitable for dynamic and resource-constrained aerial sensing environments. To address this challenge, this paper proposes an energy-aware post-quantum hybrid cryptographic framework for secure and low-latency UAV remote sensing communications in UAV–IoT mission networks. The proposed framework integrates Ascon-based authenticated encryption for low-overhead protection of remote sensing payloads and mission telemetry, ML-KEM-based post-quantum session-key establishment for long-term resilience against quantum-era threats, and an AI-driven adaptive rekeying mechanism that dynamically adjusts key-refresh decisions according to threat level, residual energy, mobility state, channel stability, anomaly density, traffic sensitivity, link type, and mission progression. Accordingly, rekeying is treated not as a static maintenance process but as an intelligent and context-aware cryptographic control function that adapts communication security to evolving mission and sensing conditions. The framework is evaluated across twenty progressively demanding scenarios involving different UAV counts, sensor densities, payload sizes, communication modes, and adversarial settings relevant to real-time remote sensing operations. Experimental results demonstrate a secure delivery rate of 99.2%, attack detection and mitigation effectiveness of 98.9%, end-to-end encryption latency of 8.7 ms, throughput of 5.03 Mbps, energy overhead of 11.6 mJ/session, rekeying overhead of 2.9 mJ/event, session resilience of 96.4%, and integrity verification success of 99.1%. These findings show that the proposed framework provides a practical and scalable contribution to post-quantum secure UAV remote sensing by unifying lightweight authenticated encryption, ML-KEM-based quantum-resilient key establishment, and AI-driven adaptive rekeying within a resilient aerial–terrestrial communication architecture.

Cyber-physical smart infrastructures integrate sensing devices, communication networks, control components, and service platforms, which makes them vulnerable to malicious activities that may evolve gradually through several attack stages. The objective of this study is to develop and evaluate a simulation-based cybersecurity framework capable of detecting a proposed novel multi-stage cyber attack and identifying its internal progression within a realistic smart infrastructure environment. To achieve this objective, a NetSim-based cyber-physical smart infrastructure was modeled to generate both normal operational traffic and staged malicious traffic. The generated traffic was captured, processed, labeled, and transformed into a stage-aware cybersecurity dataset. An artificial neural network (ANN) model was then trained and evaluated for two detection tasks: binary classification of normal versus attack traffic and multi-class classification of compromise, coordination, and execution attack stages. Twenty experimental configurations were designed to examine the model under progressively broader infrastructure contexts, including sensing, service, gateway, control, backbone, and full-span operational scenarios. The best binary testing performance was achieved in the eighteenth experimental configuration, representing a broad full-span infrastructure scenario, with 97.96% accuracy, 97.80% precision, 97.65% recall, 97.72% F1-score, and 1.06% false positive rate. For stage-aware multi-class detection, the ANN model achieved 96.97% accuracy, 96.36% macro-averaged precision, 96.20% macro-averaged recall, 96.28% macro-averaged F1-score, and 96.55% weighted F1-score. Macro-averaged metrics report the unweighted average performance across classes, while weighted F1-score accounts for class support. These results show that the proposed simulation-based framework can generate realistic attack-aware traffic data and support reliable ANN-based detection of both attack presence and attack-stage progression.