We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.
Jean Damascene Uwizeyimana, M.D., Daewon Kim, M.D., Hyunsook Lee, M.Sc., Jung-Hyun Byun, M.D., and Dongeun Yong, M.D., Ph.D.. Ann Lab Med 2020;40:306-11. https://doi.org/10.3343/alm.2020.40.4.306