Since 2019, the Mexican Government has implemented the Sembrando Vida Program (SVP) to address environmental degradation and social marginalization in rural areas. This research analyzed the SVP’s targeting mechanisms to assess the fulfillment of its objectives in the central region of the state of Guerrero, Mexico. The methodology included an analysis of the Operating Rules; a review of the beneficiary registry; the construction of environmental, social, and economic indicators; proportional stratified sampling with a 90% confidence level; and an SVP evaluation using indicators and confidence intervals. Targeting mechanisms identified agrarian subjects aged ≥ 18 years with 2.5 hectares living below the poverty line. Changes in the indicator matrix highlight a focus on food self-sufficiency and poverty levels, among others. Key results from the indicators include 100% social recovery, 62.3% of beneficiaries increased their agricultural income, and 100% application of learned environmental techniques. The intervals showed that between 26.49–42.19% of individuals joined the agricultural sector; 55.68–71.58% diversified their crops; and 86.15–95.65% made improvements in health, housing, or education. The evaluation of the SVP demonstrated its impact on environmental preservation and the improvement of the socioeconomic well-being of the rural population in the study area.