Aim: The COVID-19 outbreak continues to pose a threat to people's physical and mental health all over the world. The health professionals who are directly involved in the fight against the pandemic may experience stress during this crisis that can cause Burnout and Secondary traumatic stress. The objective of our study was to assess the burnout among physicians during COVID-19 pandemic and to determine related factors. Materials and Methods: A cross-sectional online survey was conducted. The demographical and occupational data were collected using a questionnaire and burnout level was assessed by Maslach Burnout Inventory (MBI). Results: 748 physicians took the survey. The burnout levels stated by the physicians were found to be significantly higher than before the pandemic [median before pandemic 3 (CDA: 2-4); median 4 (2-5) during pandemic; p <0.001]. Personal Accomplishment (PA), Emotional Exhaustion (EE) and Depersonalization (D) scores of participants directly providing medical services to COVID-19 cases were significantly higher (p <0.05). While EE and D scores were highest in first step workers, PA scores were highest in third step workers. PA scores were lower in man and EE scores were higher in women (p<0.05). Negative correlation was found between the age and the EE [r: (-) 0.087; p< 0.017] and D [r: (-) 0.233; p<0.001] subscale scores. Conclusion: We concluded that women, younger, first step and frontline workers had higher risks for burnout, so individual, structural, and organizational arrangements should be made by giving priority to these risky groups.

Purpose Phyllodes tumors (PTs) are uncommon fibroepithelial breast lesions that are classified as three different forms as benign phyllodes tumor (BPT), borderline phyllodes tumor (BoPT), and malignant phyllodes tumor (MPT). Conventional radiologic methods make only a limited contribution to exact diagnosis, and texture analysis data increase the diagnostic performance. In this study, we aimed to evaluate the contribution of texture analysis of US images (TAUI) of PTs in order to discriminate between BPTs and BoPTs-MPTs. Methods The number of patients was 63 (41 BPTs, 12 BoPTs, and 10 MPTs). Patients were divided into two groups (Group 1-BPT, Group 2-BoPT/MPT). TAUI with LIFEx software was performed retrospectively. An independent machine learning approach, MATLAB R2020a (Math- Works, Natick, Massachusetts) was used with the dataset with p < 0.004. Two machine learning approaches were used to build prediction models for differentiating between Group 1 and Group 2. Receiver operating characteristics (ROC) curve analyses were performed to evaluate the diagnostic performance of statistically significant texture data between phyllodes subgroups. Results In TAUI, 10 statistically significant second order texture values were identified as significant factors capable of differentiating among the two groups (p < 0.05). Both of the models of our dataset make a diagnostic contribution to the discrimination between BopTs-MPTs and BPTs. Conclusion In PTs, US is the main diagnostic method. Adding machine learning-based TAUI to conventional US findings can provide optimal diagnosis, thereby helping to choose the correct surgical method. Consequently, decreased local recurrence rates can be achieved.

Aim: This study aims to evaluate work-related anxiety among sixth-year medical students in the emergency department (ED), identify associated factors, and analyze their relationship with anxiety levels. Material and Methods: This cross-sectional survey study was conducted following approval from the ethics committee. Data were collected via the Emergency Department Work Anxiety Questionnaire (EDWAQ) and State-Trait Anxiety Inventory (STAI TX2) and the necessary analyses were performed. Results: A total of 151 sixth-year medical students participated in the study. The mean STAI TX-2 score was 44.7 ± 9.1, indicating moderate anxiety. Female students reported higher trait anxiety than males (p=0.002). The main anxiety triggers were fear of violence, managing multiple trauma patients, and handling pregnant patients with non-obstetric complaints. No significant anxiety difference was found between those who completed the ED internship and those who did not (p=0.87). However, internship experience improved confidence in specific clinical situations. Conclusion: Sixth-year students experience moderate anxiety, with females reporting higher levels. While ED internships do not reduce overall anxiety, they improve skills in certain clinical situations. Fear of violence remains the primary concern. Preinternship orientation, psychological support, and violence prevention policies could lower anxiety and enhance competence.

High altitude conditions cause changes in organism functions. Low oxygen concentration, low heat and exposure to ultraviolet rays for a long time trigger these changes. In our study, the effects of exercise at 1055m and 2500m on Malondialdehyde (MDA), Creatinine, Lactate Dehydrogenase (LDH) and Aspartate Aminotransferase (AST), Total Protein, Glucose, Cholesterol are tried to be determined. Twelve healthy individuals were included in the study. They exercised 3 hours a day for 5 days in both places. Blood samples taken into tubes with anticoagulants, both at the first day and on the fifth day, at 1055 m and 2500 m altitude before and after exercise, were centrifuged and separated into their plasma. It was found that glucose and AST (aspartate aminotransferase) increased at 2500 meters. MDA (malondialdehyde) decreased. At 1500 meters, glucose and creatinine were found to be released, while AST (aspartate aminotransferase) was decreased. Considering the samples taken 10 days after the volunteers returned from 2500 m to 1055 m, the results were found to approach 2500 m pre-exercise values. When the results of 1055 m and 2500 m were compared to the 1st and 5th days, glucose and creatinine were found to be increased both at 1050 m and at 2500 m. It is observed that LDH (lactate dehydrogenase) increased significantly at 5th of 2500m compared to 1st day. Our results showed that both exercise and high altitude affect muscle serum enzymes and glucose MDA values, but these changes do not pose a risk of disease that would require medical intervention.