Automated brain tumor segmenters typically run a “skull-stripping” pre-process to extract the brain from the 3D image, before segmenting the area of interest within the extracted volume. We demonstrate that an effective existing segmenter can be improved by replacing its skull-stripper component with one that instead uses a registration-based approach. In particular, we compare our automated brain segmentation system with the original system as well as three other approaches that differ only by using a different skull-stripper—BET, HWA, and ROBEX: (1) Over scans of 120 patients with brain tumors, our system’s segmentation accuracy (Dice score with respect to expert segmentation) is 8.6% (resp. 2.7%) better than the original system on gross tumor volumes (resp. edema); (2) Over 103 scans of controls, the new system found 92.9% (resp. 57.8%) fewer false positives on T1C (resp. FLAIR) volumes. (The other three methods were significantly worse on both tasks). Finally, the new registration-based approach is over 15% faster than the original, requiring on average only 178 CPU seconds per volume.

Fused deposition modeling (FDM) is one of the most widely adopted additive manufacturing (AM) technologies due to its accessibility and versatility; however, ensuring process reliability and product quality remains a significant challenge. This work introduces a novel methodology to evaluate the fidelity of programmed extruder head trajectories and speeds against those executed during the printing process. The approach integrates infrared thermography and image processing. A type-V ASTM D638-14 polylactic acid (PLA) specimen was fabricated using 16 layers, and its G-code data were systematically compared with kinematic variables extracted from long-wave infrared (LWIR) thermal images. The results demonstrate that the approach enables the detection of deviations in nozzle movement, providing valuable insights into layer deposition accuracy and serving as an early indicator for potential defect formation. This thermal image–based monitoring can serve as a non-invasive tool for in situ quality control (QC) in FDM, supporting process optimization and improved reliability of AM polymer components. These findings contribute to the advancement of smart sensing strategies for integration into industrial additive manufacturing workflows.