Background and Objectives: This study aimed to examine the severity of misophonia symptoms in individuals diagnosed with obsessive–compulsive disorder (OCD) and to evaluate the pattern of the relationship between misophonia and OCD symptom severity in relation to anxiety sensitivity and mindfulness. Materials and Methods: This comparative and cross-sectional study included 108 patients diagnosed with OCD according to DSM-5 criteria and 81 healthy control subjects without any psychiatric diagnosis. Participants completed the Misophonia Symptom List (MSL), Anxiety Sensitivity Index-3 (ASI-3), Mindful Attention Awareness Scale (MAAS), Yale–Brown Obsessive Compulsive Scale (Y-BOCS), and Beck Anxiety Inventory (BAI). Statistical analyses included group comparisons, Pearson correlations, multiple linear regression, and mediation analyses using the PROCESS macro. Results: MSL scores were significantly higher in the OCD group compared to the control group (104.10 ± 33.00 vs. 87.56 ± 20.07, p < 0.001). ASI-3 (33.53 ± 18.72 vs. 18.12 ± 11.55, p < 0.001) and BAI scores (20.74 ± 13.14 vs. 11.04 ± 8.47, p < 0.001) were higher; MAAS scores were lower (53.23 ± 14.92 vs. 60.72 ± 12.70, p < 0.001). In the OCD group, MSL scores were positively correlated with anxiety sensitivity (r = 0.626, p < 0.001) and Beck anxiety (r = 0.515, p < 0.001) and negatively correlated with MAAS (r = −0.357, p < 0.001). In multiple regression analysis, anxiety sensitivity was identified as the only variable significantly predicting misophonia severity (β = 0.523, p < 0.001). Mediation analyses showed that anxiety sensitivity emerged as the dominant indirect pathway between OCD symptom severity and misophonia, whereas the contribution of mindfulness was not independent of anxiety sensitivity in the serial mediation model. Conclusions: The findings indicate that misophonia symptoms are significantly elevated in individuals diagnosed with OCD and that these symptoms are particularly associated with cognitive-emotional variables such as anxiety sensitivity and mindfulness. Given the cross-sectional design, the mediation findings should be interpreted as indirect associations rather than evidence of causal pathways. Considering these variables may be useful in assessing misophonia symptoms accompanying OCD and planning clinical approaches.

Background/Objectives: Treatment non-adherence in bipolar disorder remains a major clinical challenge. Although demographic and clinical predictors have been widely studied, enduring cognitive vulnerability patterns such as early maladaptive schemas have received limited attention in relation to adherence behavior. Methods: This cross-sectional study included a total of 156 euthymic patients with bipolar disorder (HAM-D ≤ 7; YMRS ≤ 12) who were assessed using the Young Schema Questionnaire–Short Form 3, the Morisky Medication Adherence Scale, and a clinician-rated insight measure. Group differences across adherence levels were examined using ANOVA and chi-square tests. Ordinal logistic regression was conducted to identify independent factors associated with poorer adherence. Multicollinearity was evaluated, and proportional odds assumptions were tested. Results: Several schema domains differed significantly across adherence groups, with the Punishment schema demonstrating the largest effect size. In ordinal regression analysis controlling for age and insight, higher Punishment schema scores were independently associated with poorer adherence (OR = 1.14, 95% CI = 1.09–1.20, p < 0.001). Younger age and partial insight were also associated with lower adherence. Conclusions: Early maladaptive schemas—particularly punitive self-evaluative patterns—may represent cognitive correlates of treatment non-adherence in euthymic bipolar disorder. Interventions targeting self-critical schema processes may be relevant for adherence-focused strategies; however, due to the cross-sectional design, the observed relationships reflect associations only and do not allow for causal inferences.

Objective: To examine the relationships between obsessive-compulsive disorder (OCD) symptom severity, rumination, and problematic social media use. Methods: A total of 220 participants (112 patients with OCD and 108 healthy controls) completed the Positive and Negative Rumination Scale (PANRS) and the Bergen Social Media Addiction Scale (BSMAS). OCD diagnoses were confirmed using the SCID-5-CV, and symptom severity was assessed with the Yale-Brown Obsessive Compulsive Scale. Between-group comparisons, correlation, mediation, and hierarchical regression analyses were performed. Results: Patients with OCD showed significantly higher problematic social media use and negative rumination, and lower positive rumination than controls (all P < 0.001). Problematic social media use was positively correlated with OCD symptom severity and negative rumination and negatively correlated with positive rumination. Negative rumination partially mediated the relationship between OCD symptom severity and problematic social media use and remained a significant predictor independent of age and OCD severity. Conclusions: Problematic social media use is elevated in OCD and is associated with symptom severity and maladaptive ruminative processes. Negative rumination may represent a cognitive mechanism linking OCD symptoms to problematic social media use.

Objective: This study aimed to evaluate posttraumatic stress symptoms among healthcare workers in the third year following the Kahramanmaraş-centered earthquakes and to examine the relationships of these symptoms with perceived social support, personality traits, anxiety, and depression levels. Method: A total of 174 healthcare workers who were employed at the same hospital during the February 6, 2023 earthquakes were included in the study. Participants were evaluated using the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), the Multidimensional Scale of Perceived Social Support (MSPSS), the Revised Abbreviated Eysenck Personality Questionnaire (EPQR-A), the Beck Anxiety Inventory (BAI), and the Beck Depression Inventory (BDI). Results: The mean age of the participants was 35.94±9.40 years, and 65.5% were female. Posttraumatic stress symptom severity was positively correlated with depressive, and anxiety symptoms, and neuroticism, and negatively correlated with perceived social support. PCL-5 scores were significantly higher among participants who worked in the disaster area during the first month after the earthquakes, experienced housing damage, were displaced from their homes for at least one week, relocated their residence, experienced housing problems, or had a physically injured relative. In the multiple linear regression analysis, anxiety symptoms and perceived social support were independently associated with posttraumatic stress symptom severity (R²=0.496). Conclusion: Approximately three years after the Kahramanmaraş-centered earthquakes, posttraumatic stress symptoms among healthcare workers were associated with anxiety levels, perceived social support, and secondary stressors arising in the aftermath of the disaster.

Orthorexic tendencies and their measurement remain understudied in transgender adults. This cross-sectional study conducted a preliminary psychometric evaluation of the Turkish ORTO-11 and examined psychological correlates of orthorexic tendencies in a clinically recruited sample of transgender adults undergoing psychiatric evaluation before gender-affirming hormonal or surgical treatment. Eighty participants completed the ORTO-11, Health Anxiety Inventory, Psychache Scale, Self-Compassion Scale, and Multidimensional Scale of Perceived Social Support. Internal consistency analyses, confirmatory factor analysis, Spearman correlations, robust regression, and indirect-effect analysis were conducted. The ORTO-11 showed good internal consistency (Cronbach’s α = 0.88; McDonald’s ω = 0.89), and confirmatory factor analysis supported a unidimensional structure with acceptable model fit indices. Lower ORTO-11 scores, indicating greater orthorexic tendencies, were associated with higher health anxiety and psychological pain and with lower self-compassion and perceived social support. In multivariable analysis, psychological pain was the only significant independent correlate of ORTO-11 scores. Bootstrap analysis suggested that psychological pain statistically accounted for part of the association between health anxiety and orthorexic tendencies. These findings provide preliminary support for the Turkish ORTO-11 as a self-report measure of orthorexic tendencies in this clinically recruited transgender sample, but the scale should not be interpreted as a diagnostic instrument for orthorexia nervosa.