Background/Objectives: Despite being a vaccine-preventable disease, influenza continues to pose a significant global health challenge, with clinical severity increasing at the extremes of age. This study aimed to describe influenza hospitalizations and hospital-related fatality rates in Poland in the pre-pandemic and COVID-19 periods. Methods: This retrospective population-based study included 39,604 hospital admissions with a diagnosis of influenza in Poland. Data were extracted from the National General Hospital Morbidity Study conducted by the National Institute of Public Health for the period 2016–2022. Results: Based on the hospital registry and data on the general population, an upward trend in hospitalization rates was observed in 2016–2020. In subsequent years, the lowest hospitalization rates were observed in 2021 and the highest ones in 2022, accounting for 1.3 and 30.3 hospitalizations per 100,000, respectively. Two hospitalization peaks were observed, one for children 0–5 and the other for adults 65–70 years of age. After the COVID-19 outbreak in Poland, an increased percentage of hospitalizations was observed in children and adolescents, and a decreased frequency was found in the elderly. The overall hospitalization fatality rate during the study period accounted for 2.9%, and the authors observed a decrease in the in-hospital fatality rate after the COVID-19 outbreak compared to the pre-pandemic period (3.4% vs. 2.1%, p < 0.001). Conclusions: This study highlights recent trends in influenza hospitalizations and in-hospital mortality before and during the COVID-19 pandemic in Poland, providing important data for optimizing prevention strategies and serving as a foundation for global comparative analyses.

Background/Objectives: Sjögren’s disease (SjD) is a chronic autoimmune disease primarily affecting exocrine glands, often leading to systemic complications and comorbidities. While SjD is known to impact quality of life, research on hospitalization trends, demographic characteristics, and factors influencing hospital stay duration remains limited. This study aims to analyze hospitalizations due to SjD in Poland between 2012 and 2023, identifying key trends, risk factors, and healthcare implications. Methods: A retrospective analysis was conducted using data from the National General Hospital Morbidity Study, covering 13,999 first-time hospitalizations with an SjD diagnosis (ICD-10: M35.0). Descriptive statistics were applied to evaluate patient demographics, hospitalization trends, and comorbidities. The Mann–Whitney U test and chi-square test were used to compare groups, while a linear regression model identified predictors of hospital stay duration. Results: Women accounted for 90.3% of hospitalizations, with a median age of 57 years, compared to 53 years for men. The hospitalization rate fluctuated over time, with a decline in 2020, possibly due to the COVID-19 pandemic, followed by an increase in 2021–2023. The most common comorbidities included musculoskeletal disorders (17.8%), cardiovascular diseases (16.6%), and endocrine disorders (13.6%). Women had longer hospital stays than men (median 5 vs. 4 days, p < 0.001). Older patients and those admitted in emergency settings had significantly longer hospital stays. The overall mortality rate was low (0.2%), with a slightly higher but statistically insignificant mortality rate among men. Conclusions: The study highlighted the increasing burden of SjD-related hospitalizations and the need for improved outpatient management to reduce inpatient admissions. Factors such as older age, female sex, and emergency admissions were associated with prolonged hospitalization. Strengthening early diagnostic strategies, optimizing access to specialist care, and monitoring comorbidities could enhance patient outcomes and reduce hospital resource utilization.