Based on the viscoelastic artificial boundary theory and the equivalent seismic load input method, this study develops a three-dimensional time-domain input method for obliquely incident SV waves; the validation of this input method was verified, and seismic response analysis was conducted on a biased rock tunnel. The results indicate that the structural seismic response under oblique wave incidence differs significantly from that under vertical incidence. With an increase in the incidence angle, the tunnel’s stress, acceleration, and damage zones all tend to concentrate toward the left arch foot and waist. At different times during the earthquake, stresses and plastic zones develop at the tunnel shoulder, along with the obliquely incident seismic wave propagation, and the stresses and plastic zones gradually concentrate in the direction facing the waves, causing damage at the tunnel foot near the earthquake source. Therefore, in tunnel structures located near the epicenter of an earthquake, the damage evolution at the foot of the tunnel facing the seismic waves should garner more attention.

Land subsidence in the Yellow River Floodplain, approaching 60 mm/year, is severely exacerbated by annual groundwater oscillations of 3 to 8 m. Conventional hydro-mechanical models, which primarily rely on effective stress principles, often struggle to fully capture the moisture-induced structural degradation of calcareous cemented soils under such hydraulic disturbances. To address this theoretical gap, we conducted a multifactor orthogonal triaxial experiment to quantitatively decouple the macroscopic factors governing the hydro-mechanical degradation. The results reveal that moisture content acts as the absolute dominant driver, accounting for 81.65% of the variance in macroscopic shear strength variance and completely overwhelming the mechanical advantages provided by initial compaction. A generalized dual-path water-sensitive damage model was explicitly derived, mathematically uncovering a fundamental asynchronous degradation mechanism. Cohesion exhibits an inward-concave, brittle fracture trajectory, which is macroscopically inferred to be associated with the water-induced softening of calcareous bonds (phase-transition parameter 0.81, maximum allocation 75.1%). Conversely, the internal friction angle demonstrates an outward-convex, hysteretic decline (parameter 1.59), maintaining structural interlocking until severe water-film lubrication occurs. By decoupling highly state-dependent initial strength parameters from invariant degradation operators, the modified Mohr–Coulomb model achieved exceptional forward blind-prediction accuracy. Validations across distinct initial skeletal structures constrained relative prediction errors strictly between −19.3% and +13.7% without any subjective parameter recalibration. The quantified extreme vulnerability theoretically proves that minor water infiltration can instantly eradicate over 75% of cohesive strength, necessitating a paradigm shift from shallow mechanical compaction to stringent waterproofing in regional engineering practices.