Background: With advances in cancer diagnosis and therapy, survival after childhood and young-adult cancers has improved markedly. As survivorship extends, understanding long-term health sequelae, including obstetric outcomes, has become increasingly important. However, the reproductive safety of pregnancy following cancer remains insufficiently characterized. This systematic review and meta-analysis aims to provide a comprehensive evaluation of obstetric outcomes following pregnancy in survivors of childhood and young-adult cancers. Methods: We conducted a systematic review and meta-analysis (PROSPERO: CRD42024573707) of PubMed, Embase, and Cochrane databases to identify controlled studies assessing obstetric complications among female cancer survivors, published between 1 January 2000 and 31 June 2024. Random effects meta-analyses were used to estimate pooled risk ratios (RRs) with 95% confidence intervals (CIs). Heterogeneity, subgroup analyses, and meta-regression were performed to identify sources of variation. Results: Of 6032 records screened, 16 studies involving 89,123 survivors and 21,569,191 controls were included. Cancer survivorship was associated with higher risks of preeclampsia (RR 1.37, 95% CI 1.17–1.62), gestational diabetes (RR 1.29, 95% CI 1.05–1.59), and miscarriage (RR 1.16, 95% CI 1.01–1.35), but not with anemia in pregnancy (RR 1.16, 95% CI 0.98–1.39) or hypertensive disorders (RR 1.21, 95% CI 0.99–1.49). Cancer type emerged as a potential prognostic factor for preeclampsia. Conclusions: Female cancer survivors are at significantly increased risk of major obstetric complications, underscoring the need for anticipatory preconception counselling and enhanced antenatal surveillance. Future research should delineate cancer- and treatment-specific risks to inform precision reproductive care in this growing survivorship population.

Objectives: This study aims to investigate the association between self-reported pornographic consumption habits and anxiety and depression. Methods: We systematically searched PubMed, Embase, Cochrane, and PsycINFO for all studies that examined anxiety and depression across consumption habits in pornographic content consumers (PCCs). PRISMA reporting guidelines were followed. Random effects meta-analyses were conducted for the primary analysis using correlation coefficients (CORs) and standardised mean differences (SMDs). A synthesis without a meta-analysis approach was further performed to examine factors affecting pornography consumption. Results: A total of 19 studies were included. The overall meta-analysis indicated significant positive correlations between pornographic consumption and both anxiety (COR = 0.16; 95% CI: 0.08; 0.25) and depression (COR = 0.24; 95% CI: 0.15; 0.32). Exploratory study-level subgroup analyses suggested that problematic consumption or addiction, but not general consumption, was associated with anxiety and depression. A stronger anxiety correlation was also observed in samples with a mean age ≤25 years compared with older users (COR = 0.22 vs. COR = 0.09; p = 0.0321). Systematically reviewing the studies showed that male gender and younger age significantly increased pornographic content consumption. Conclusions: The study found significant positive correlations between pornographic consumption and both anxiety and depression, with an increased effect on younger users. These findings suggest that pornography consumption habits may be important to psychosocial assessment, although substantial heterogeneity, residual confounding, and the observational nature of the evidence preclude causal inference.