Jelena Jakab

Dr. Jelena Jakab

Faculty of Dental Medicine and Health Osijek
+1
orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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3 February 2019 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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LKLucija Kuna
Lucija Kuna
JJJelena Jakab
Jelena Jakab
RSRobert Smolić
Robert Smolić
NRNikola Raguz-Lucic
Nikola Raguz-Lucic
AVAleksandar Včev
Aleksandar Včev
MSMartina Smolic
Martina Smolic
Peptic ulcer is a chronic disease affecting up to 10% of the world’s population. The formation of peptic ulcers depends on the presence of gastric juice pH and the decrease in mucosal defenses. Non-steroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori (H. pylori) infection are the two major factors disrupting the mucosal resistance to injury. Conventional treatments of peptic ulcers, such as proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists, have demonstrated adverse effects, relapses, and various drug interactions. On the other hand, medicinal plants and their chemical compounds are useful in the prevention and treatment of numerous diseases. Hence, this review presents common medicinal plants that may be used for the treatment or prevention of peptic ulcers.

1 January 2021 in Diabetes, Metabolic Syndrome and Obesity
Verified
Journal Article
Open access
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JJJelena Jakab
Jelena Jakab
BMBlaženka Miškić
Blaženka Miškić
ŠMŠtefica Mikšić
Štefica Mikšić
BJBrankica Juranić
Brankica Juranić
VĆVesna Ćosić
Vesna Ćosić
AVAleksandar Včev
Aleksandar Včev
Obesity is recognized as a severe threat to overall human health and is associated with type 2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal expansion of white adipose tissue involves increasing the existing adipocytes’ cell size or increasing the number through the differentiation of new adipocytes. Adipogenesis is a process of proliferation and differentiation of adipocyte precursor cells in mature adipocytes. As a key process in determining the number of adipocytes, it is a possible therapeutic approach for obesity. Therefore, it is necessary to identify the molecular mechanisms involved in adipogenesis that could serve as suitable therapeutic targets. Reducing bodyweight is regarded as a major health benefit. Limited efficacy and possible side effects and drug interactions of available anti-obesity treatment highlight a constant need for finding novel efficient and safe anti-obesity ingredients. Numerous studies have recently investigated the inhibitory effects of natural products on adipocyte differentiation and lipid accumulation. Possible anti-obesity effects of natural products include the induction of apoptosis, cell-cycle arrest or delayed progression, and interference with transcription factor cascade or intracellular signaling pathways during the early phase of adipogenesis.

ŠMŠtefica Mikšić
Štefica Mikšić
BUBoran Uglešić
Boran Uglešić
JJJelena Jakab
Jelena Jakab
DHDubravka Holik
Dubravka Holik
AMAndrea Milostić-Srb
Andrea Milostić-Srb
DDDunja Degmečić
Dunja Degmečić
Background: Postpartum depression is a psychiatric disorder that starts from the second to the sixth week after birth. Breastfeeding is considered a protective factor for postpartum mood swings. This paper aims to examine the effect of breastfeeding on postpartum depression and anxiety, and how it affects child development. Methods: The study included 209 pregnant women, 197 puerperea, and 160 women at the end of the third month after delivery, followed through three time-points. The instruments used in the study were the Edinburgh Postpartum Depression Scale (EPDS), Beck’s Depression Inventory (BDI), and Beck’s Anxiety Inventory (BAI). Results: Postpartum mothers with low risk of PPD breastfed their children more often than mothers with a mild or severe risk of perinatal depression. Mean values on the BDI scale three months after giving birth were higher in mothers who did not breastfeed their child (M = 3.53) than those who did breastfeed their child (M = 2.28). Postpartum anxiety measured by BAI was statistically negatively correlated (rs-, 430) with the duration of breastfeeding. Conclusion: Nonbreastfeeding mothers are more depressed and anxious compared to breastfeeding mothers.

28 March 2019 in Journal of Clinical and Translational Hepatology
Verified
Journal Article
Open access
PDF file
LKLucija Kuna
Lucija Kuna
JJJelena Jakab
Jelena Jakab
RSRobert Smolic
Robert Smolic
GWGeorge Y Wu
George Y Wu
MSMartina Smolic
Martina Smolic
Hepatitis C virus (HCV) has been shown to affect many tissues other than liver. However, of the many extrahepatic manifestations (EMs) that have been associated with HCV, including cryoglobulinemia, lymphoma, insulin resistance, type 2 diabetes and neurological disorders, only a few have been shown to be directly related to HCV infection of extrahepatic tissues. HCV-triggered immune-mediated mechanisms account for most of the EMs. It is estimated that up to 74% of patients with chronic hepatitis C can develop at least one EM. All HCV patients with EMs should be considered for antiviral therapy, although not all will resolve with sustained virological response.

26 July 2017 in Journal of Occupational Medicine and Toxicology
Verified
Journal Article
Open access
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BJBrankica Juranić
Brankica Juranić
ŽRŽeljko Rakošec
Željko Rakošec
JJJelena Jakab
Jelena Jakab
ŠMŠtefica Mikšić
Štefica Mikšić
SVSuzana Vuletić
Suzana Vuletić
IBIvka Blažević
Ivka Blažević
Tobacco use is the second major cause of morbidity and the 4th most common health risk factor in the world. Medical professionals have a critical role in the process of smoking cessation both as advisers and behavioural models for the citizens. The aim of this study was to investigate the prevalence of smoking among health care professionals, their smoking habits and personal attitudes toward smoking, role and the responsibility of health care professionals in the prevention of smoking. Out of the total number of examinees, 175 (35,1%) are active smokers, 29 (5,8%) are former smokers, and 295 (59,1%) are non-smokers. Nurses with secondary education disagree the most with the claim that passive smoking is more harmful to health (χ2 test, p = .008), also with the claim that the introduced Smoking Act is fair to smokers (χ2 test, p = .021). More nurses with secondary education disagree completely or partially that one should pay attention to smoking in the presence of non-smokers (χ2 test, p = .012). Training programs for health care workers are needed to improve their ability in smoking cessation techniques to provide active support to their patients.

22 July 2020 in BMC Medical Education
Verified
Journal Article
Open access
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Jakov MilićJakov Milić
Jakov Milić
Ivana ŠkrlecIvana Škrlec
Ivana Škrlec
IVIva Milić Vranješ
Iva Milić Vranješ
JJJelena Jakab
Jelena Jakab
VPVera Plužarić
Vera Plužarić
Marija HefferMarija Heffer
Marija Heffer
Background: The most crucial decision in the physician’s career after graduation is undoubtedly the choice of specialization. It is conditioned by many factors such as intellectual challenges, clinical experience, economic and social influences. The aim of this study was to determine whether personality traits affect the choice of medical specialty at the University of Osijek, Croatia.Methods: This cross-sectional study included a total of 407 medical students. To assess the personality traits, the IPIP Big-Five questionnaire was used.Results: There were no differences in four of the five personality traits of the Big-Five questionnaire when comparing the groups based on their specialty preference: extroversion, agreeableness, conscientiousness, and emotional stability. A significant difference was found for openness to experience (intellect/imagination) trait, where students who preferred psychiatry specialties achieved the highest score, and those who chose public health specialties scored the lowest. We observed no significant effect between gender and specialty preference based on personality traits.Conclusions: We could not attribute the differences in personality traits to specialty preference. Medical students with higher scores on agreeableness and openness (intellect/imagination) scales were more inclined to psychiatric specialties, and more conscientiousness students preferred the anesthesiology and emergency medicine specialties. Even if variations in personality traits do not exist across different specialties, many other factors influence specialty preference.