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The study’s aim was to characterize the composition of Nigella sativa seed (NSO) and grape seed (GSO) oils, and to evaluate their cardioprotective and anti-inflammatory effect on isoproterenol (ISO)-induced ischemia in rats. Materials and Methods: NSO and GSO supplements were physicochemically characterized. Liquid chromatography–mass spectrometry (HPLC-MS), Fourier-transform infrared spectroscopy (FTIR), and gas chromatography–mass spectrometry (GC-MS) analyses were used to determine the phytochemical composition in the oils. Total polyphenol content (TPC) and in vitro antioxidant activity were also determined. Pretreatment with 4 mL/kg/day NSO or GSO was administered to rats for 14 days. The experimental ischemia was induced by a single administration of ISO 45 mg/kg after 14 days. An electrocardiogram (ECG) was performed initially and 24 h after ISO. Biological evaluation was done at the end of experiment. Results: The HPLC-MS, GC-MS, and FTIR analyses showed that both NSO and GSO are important sources of bioactive compounds, especially catechin and phenolic acids in GSO, while NSO was enriched in flavonoids and thymol derivatives. Pretreatment with GSO and NSO significantly reduced ventricular conduction, prevented the cardiotoxic effect of ISO in ventricular myocardium, and reduced the level of proinflammatory cytokines and CK-Mb. Conclusion: Both NSO and GSO were shown to have an anti-inflammatory and cardioprotective effect in ISO-induced ischemia.
Ioana Bocsan; Raluca Pop; Octavia Sabin; Elias Sarkandy; Paul-Mihai Boarescu; Ştefan Roşian; Poliana Leru; Veronica Chedea; Sonia Socaci; Anca Buzoianu. Comparative Protective Effect of Nigella sativa Oil and Vitis vinifera Seed Oil in an Experimental Model of Isoproterenol-Induced Acute Myocardial Ischemia in Rats. Molecules 2021, 26, 3221 .
AMA StyleIoana Bocsan, Raluca Pop, Octavia Sabin, Elias Sarkandy, Paul-Mihai Boarescu, Ştefan Roşian, Poliana Leru, Veronica Chedea, Sonia Socaci, Anca Buzoianu. Comparative Protective Effect of Nigella sativa Oil and Vitis vinifera Seed Oil in an Experimental Model of Isoproterenol-Induced Acute Myocardial Ischemia in Rats. Molecules. 2021; 26 (11):3221.
Chicago/Turabian StyleIoana Bocsan; Raluca Pop; Octavia Sabin; Elias Sarkandy; Paul-Mihai Boarescu; Ştefan Roşian; Poliana Leru; Veronica Chedea; Sonia Socaci; Anca Buzoianu. 2021. "Comparative Protective Effect of Nigella sativa Oil and Vitis vinifera Seed Oil in an Experimental Model of Isoproterenol-Induced Acute Myocardial Ischemia in Rats." Molecules 26, no. 11: 3221.
The study aimed at assessing effects of partial replacement (0–40%) of wheat flour with roasted flaxseed flour (RFSF) on the quality attributes of biscuits. Nutritional, antioxidative, volatile and sensory properties, as well as texture analysis and the contents of macroelements and microelement were studied. Increasing RFSF content in biscuits resulted in a significant increase (p< 0.05) in protein (from 8.35% to 10.77%), fat (from 15.19% to 28.34%) and ash (from 1.23% to 2.60%) while the hardness and spread factor of the biscuits decreased with the increased level of roasted flaxseed flour. Moreover, the addition of 40% RFSF registered a positive influence on the fibre content of the final baked biscuits, increasing its value about 6.7-fold than in the control sample. Total phenolic content, antioxidant activity and biscuits’ aroma volatile profile increased their amounts with RFSF addition. The nutritional, textural and sensorial results of the present study demonstrated that 25% RFSF could be added in the biscuits manufacturing without affecting the biscuits aftertaste, offering promising healthy and nutritious alternative to consumers.
Simona Man; Laura Stan; Adriana Păucean; Maria Chiş; Vlad Mureşan; Sonia Socaci; Anamaria Pop; Sevastiţa Muste. Nutritional, Sensory, Texture Properties and Volatile Compounds Profile of Biscuits with Roasted Flaxseed Flour Partially Substituting for Wheat Flour. Applied Sciences 2021, 11, 4791 .
AMA StyleSimona Man, Laura Stan, Adriana Păucean, Maria Chiş, Vlad Mureşan, Sonia Socaci, Anamaria Pop, Sevastiţa Muste. Nutritional, Sensory, Texture Properties and Volatile Compounds Profile of Biscuits with Roasted Flaxseed Flour Partially Substituting for Wheat Flour. Applied Sciences. 2021; 11 (11):4791.
Chicago/Turabian StyleSimona Man; Laura Stan; Adriana Păucean; Maria Chiş; Vlad Mureşan; Sonia Socaci; Anamaria Pop; Sevastiţa Muste. 2021. "Nutritional, Sensory, Texture Properties and Volatile Compounds Profile of Biscuits with Roasted Flaxseed Flour Partially Substituting for Wheat Flour." Applied Sciences 11, no. 11: 4791.
Currently, extrudates are considered unhealthy products, being characterized as high in calories; rich in fat, sugar, and salt; and low in nutritional compounds. The aim of this study was to assess the influence of lucerne (Medicago sativa) on the physicochemical, nutritional, and functional characteristics of corn extrudates. In order to achieve these goals, water content, water activity, expansion index, bulk density, porosity, hygroscopicity, optical properties, antioxidant activity, individual phenolic acids, folates, individual flavonoids, and volatile compounds were analyzed. The results showed that the typical characteristics of corn extrudates such as expansion, crunchiness, and density were maintained with 10% lucerne addition, highlighting a strong negative Pearson correlation (p < 0.05) between all studied parameters and lucerne addition. On the other hand, the lucerne addition caused a linear increase of bioactive compounds, showing positive Pearson correlations between flavonoids, folates, and antioxidant activity. The volatile profile of corn extrudates improved with the addition of lucerne leading to volatile compounds such as limonene, β-mircene, and hexanal. Overall, considering the textural, nutritional, and functional characteristics of corn extrudates, we determined that a percentage addition on 10% lucerne could be successfully used in the manufacturing of corn extrudates.
Marta Igual; Maria Chiş; Sonia Socaci; Dan Vodnar; Floricuța Ranga; Javier Martínez-Monzó; Purificación García-Segovia. Effect of Medicago sativa Addition on Physicochemical, Nutritional and Functional Characteristics of Corn Extrudates. Foods 2021, 10, 928 .
AMA StyleMarta Igual, Maria Chiş, Sonia Socaci, Dan Vodnar, Floricuța Ranga, Javier Martínez-Monzó, Purificación García-Segovia. Effect of Medicago sativa Addition on Physicochemical, Nutritional and Functional Characteristics of Corn Extrudates. Foods. 2021; 10 (5):928.
Chicago/Turabian StyleMarta Igual; Maria Chiş; Sonia Socaci; Dan Vodnar; Floricuța Ranga; Javier Martínez-Monzó; Purificación García-Segovia. 2021. "Effect of Medicago sativa Addition on Physicochemical, Nutritional and Functional Characteristics of Corn Extrudates." Foods 10, no. 5: 928.
Food packaging is an area of interest not just for food producers or food marketing, but also for consumers who are more and more aware about the fact that food packaging has a great impact on food product quality and on the environment. The most used materials for the packaging of food are plastic, glass, metal, and paper. Still, over time edible films have become widely used for a variety of different products and different food categories such as meat products, vegetables, or dairy products. For example, proteins are excellent materials used for obtaining edible or non-edible coatings and films. The scope of this review is to overview the literature on protein utilization in food packages and edible packages, their functionalization, antioxidant, antimicrobial and antifungal activities, and economic perspectives. Different vegetable (corn, soy, mung bean, pea, grass pea, wild and Pasankalla quinoa, bitter vetch) and animal (whey, casein, keratin, collagen, gelatin, surimi, egg white) protein sources are discussed. Mechanical properties, thickness, moisture content, water vapor permeability, sensorial properties, and suitability for the environment also have a significant impact on protein-based packages utilization.
Vlad Mihalca; Andreea Kerezsi; Achim Weber; Carmen Gruber-Traub; Jürgen Schmucker; Dan Vodnar; Francisc Dulf; Sonia Socaci; Anca Fărcaș; Carmen Mureșan; Ramona Suharoschi; Oana Pop. Protein-Based Films and Coatings for Food Industry Applications. Polymers 2021, 13, 769 .
AMA StyleVlad Mihalca, Andreea Kerezsi, Achim Weber, Carmen Gruber-Traub, Jürgen Schmucker, Dan Vodnar, Francisc Dulf, Sonia Socaci, Anca Fărcaș, Carmen Mureșan, Ramona Suharoschi, Oana Pop. Protein-Based Films and Coatings for Food Industry Applications. Polymers. 2021; 13 (5):769.
Chicago/Turabian StyleVlad Mihalca; Andreea Kerezsi; Achim Weber; Carmen Gruber-Traub; Jürgen Schmucker; Dan Vodnar; Francisc Dulf; Sonia Socaci; Anca Fărcaș; Carmen Mureșan; Ramona Suharoschi; Oana Pop. 2021. "Protein-Based Films and Coatings for Food Industry Applications." Polymers 13, no. 5: 769.
The efficiency of some films prepared from heat-denatured whey protein isolate solutions on the quality and shelf-life of brook trout samples during storage at 4 °C was studied in this research (WPIf-a film based on whey protein isolate and WPIf+2.5%TEO-a film based on whey protein isolate incorporated with 2.5% tarragon essential oil). The control and covered fish samples were periodically assessed (at 3 days) over 15 days of storage for the physicochemical (pH; EC, electrical conductivity; TVB-N, total volatile basic nitrogen; TBARS, thiobarbituric acid reactive substances; color), microbiological (TVC, total viable count; PTC, psychrotrophic count; LAB, lactic acid bacteria; H2S-producing bacteria), and sensory properties (color discoloration; odor; overall acceptability). The WPIf+2.5%TEO has proven enhanced quality preservation effects compared to WPIf by showing lower values for physicochemical parameters, lower microbial loads, and higher sensory scores in the fish sample. All these effects have led to an extension of the sample’s shelf-life. In conclusion, the tarragon essential oil has conferred antioxidant and antimicrobial properties to the film. Thus, the WPIf+2.5%TEO could be a promising material for the packaging of fresh brook trout during refrigerated storage.
Maria-Ioana Socaciu; Melinda Fogarasi; Elemér Simon; Cristina Semeniuc; Sonia Socaci; Andersina Podar; Dan Vodnar. Effects of Whey Protein Isolate-Based Film Incorporated with Tarragon Essential Oil on the Quality and Shelf-Life of Refrigerated Brook Trout. Foods 2021, 10, 401 .
AMA StyleMaria-Ioana Socaciu, Melinda Fogarasi, Elemér Simon, Cristina Semeniuc, Sonia Socaci, Andersina Podar, Dan Vodnar. Effects of Whey Protein Isolate-Based Film Incorporated with Tarragon Essential Oil on the Quality and Shelf-Life of Refrigerated Brook Trout. Foods. 2021; 10 (2):401.
Chicago/Turabian StyleMaria-Ioana Socaciu; Melinda Fogarasi; Elemér Simon; Cristina Semeniuc; Sonia Socaci; Andersina Podar; Dan Vodnar. 2021. "Effects of Whey Protein Isolate-Based Film Incorporated with Tarragon Essential Oil on the Quality and Shelf-Life of Refrigerated Brook Trout." Foods 10, no. 2: 401.
The evolution during ripening on the quality of Apuseni cheese was studied in this research. The cheese samples were controlled and evaluated periodically (at 4 months) during 16 months of storage (at 2–8 °C) for physicochemical parameters (pH, moisture, fat, fat in dry matter, total protein, ash, NaCl), microbiological (total combined yeasts and molds count (TYMC), total viable count (TVC), Escherichia coli, Staphylococcusaureus, Salmonella, lactic acid bacteria (LAB)), fatty acids (FA) and volatile compounds. For better control of the quality of the cheese, the storage space was evaluated for TYMC and TVC. The ripening period showed improved effects on the quality of the cheese, showing lower values for moisture and pH and an increase in macronutrients. Both the cheese samples and the storage space were kept within the allowed microbiological limits. Lipids are predominant, the predominant FAs being saturated fatty acids (SFAs), which decrease, while monounsaturated fatty acids (MUFAs) increase. During ripening, the microbiological and chemical changes result in the development of flavor. Major volatile compounds such as 2-heptanone show accumulations, while acetophenone, limonene, or thymol show a decrease. In conclusion, Apuseni ripening cheese clearly involves a complex series of transformations, leading to a ripening cheese with improved nutritional and aromatic characteristics.
Crina Mureşan; Romina Marc; Cristina Anamaria Semeniuc; Sonia Ancuţs Socaci; Anca Fărcaş; Dulf Fracisc; Carmen Rodica Pop; Ancuţa Rotar; Andreea Dodan; Vlad Mureşan; Andruţa Mureşan. Changes in Physicochemical and Microbiological Properties, Fatty Acid and Volatile Compound Profiles of Apuseni Cheese during Ripening. Foods 2021, 10, 258 .
AMA StyleCrina Mureşan, Romina Marc, Cristina Anamaria Semeniuc, Sonia Ancuţs Socaci, Anca Fărcaş, Dulf Fracisc, Carmen Rodica Pop, Ancuţa Rotar, Andreea Dodan, Vlad Mureşan, Andruţa Mureşan. Changes in Physicochemical and Microbiological Properties, Fatty Acid and Volatile Compound Profiles of Apuseni Cheese during Ripening. Foods. 2021; 10 (2):258.
Chicago/Turabian StyleCrina Mureşan; Romina Marc; Cristina Anamaria Semeniuc; Sonia Ancuţs Socaci; Anca Fărcaş; Dulf Fracisc; Carmen Rodica Pop; Ancuţa Rotar; Andreea Dodan; Vlad Mureşan; Andruţa Mureşan. 2021. "Changes in Physicochemical and Microbiological Properties, Fatty Acid and Volatile Compound Profiles of Apuseni Cheese during Ripening." Foods 10, no. 2: 258.
One of the biggest challenges in managing the food sector during a pandemic crisis is sustaining a robust food security system and adopting the right strategies in correlating the consumers’ needs and requirements with those of food safety, the producers, the distribution chain, the economic environment, and waste management. The restrictions on people’s global movement, commodities, and services and the measures taken to reduce the spread of COVID-19 have disrupted food environments around the world and forced us to collectively redesign and optimize our systems using existing resources from a more sustainable perspective. This paper offers an overview of the implications of COVID-19 for the food supply chain and discusses several potential strategies for tackling short- and long-term adverse effects resulting from the pandemic.
Anca Farcas; Charis Galanakis; Carmen Socaciu; Oana Pop; Dorin Tibulca; Adriana Paucean; Mirela Jimborean; Melinda Fogarasi; Liana Salanta; Maria Tofana; Sonia Socaci. Food Security during the Pandemic and the Importance of the Bioeconomy in the New Era. Sustainability 2020, 13, 150 .
AMA StyleAnca Farcas, Charis Galanakis, Carmen Socaciu, Oana Pop, Dorin Tibulca, Adriana Paucean, Mirela Jimborean, Melinda Fogarasi, Liana Salanta, Maria Tofana, Sonia Socaci. Food Security during the Pandemic and the Importance of the Bioeconomy in the New Era. Sustainability. 2020; 13 (1):150.
Chicago/Turabian StyleAnca Farcas; Charis Galanakis; Carmen Socaciu; Oana Pop; Dorin Tibulca; Adriana Paucean; Mirela Jimborean; Melinda Fogarasi; Liana Salanta; Maria Tofana; Sonia Socaci. 2020. "Food Security during the Pandemic and the Importance of the Bioeconomy in the New Era." Sustainability 13, no. 1: 150.
Five selected wild edible mushrooms from Romania (Agaricus bisporus, Pleurotus ostreatus, Cantharellus cibarius, Boletus edulis, and Lactarius piperatus) were investigated for their antioxidant potential using an ABTS spectrophotometric assay. Among the selected mushrooms, B. edulis displayed the highest radical scavenging activity and the greatest phenolic content, measured by the Folin–Ciocalteu reagent method. The total flavonoids were quantified using the aluminum chloride colorimetric method, with the extract of B. edulis being the richest. L. piperatus and B. edulis mushrooms exhibited the strongest antibacterial activity against S. aureus and E. coli. The content of trace elements was determined using an atomic absorption spectrometer, and it was found that K and Mg were the main metals present in all the selected mushroom species. The obtained results suggest that the studied wild edible mushrooms are natural functional matrices, and may have potential to be used as natural antioxidants if they are introduced into the daily diet.
Melinda Fogarasi; Zorița Maria Diaconeasa; Carmen Rodica Pop; Szabolcs Fogarasi; Cristina Anamaria Semeniuc; Anca Corina Fărcaş; Dorin Țibulcă; Claudiu-Dan Sălăgean; Maria Tofană; Sonia Ancuța Socaci. Elemental Composition, Antioxidant and Antibacterial Properties of Some Wild Edible Mushrooms from Romania. Agronomy 2020, 10, 1972 .
AMA StyleMelinda Fogarasi, Zorița Maria Diaconeasa, Carmen Rodica Pop, Szabolcs Fogarasi, Cristina Anamaria Semeniuc, Anca Corina Fărcaş, Dorin Țibulcă, Claudiu-Dan Sălăgean, Maria Tofană, Sonia Ancuța Socaci. Elemental Composition, Antioxidant and Antibacterial Properties of Some Wild Edible Mushrooms from Romania. Agronomy. 2020; 10 (12):1972.
Chicago/Turabian StyleMelinda Fogarasi; Zorița Maria Diaconeasa; Carmen Rodica Pop; Szabolcs Fogarasi; Cristina Anamaria Semeniuc; Anca Corina Fărcaş; Dorin Țibulcă; Claudiu-Dan Sălăgean; Maria Tofană; Sonia Ancuța Socaci. 2020. "Elemental Composition, Antioxidant and Antibacterial Properties of Some Wild Edible Mushrooms from Romania." Agronomy 10, no. 12: 1972.
Attenuated total reflectance-Fourier transform infrared ppectroscopy (ATR-FTIR) proved to be a reliable, rapid, and easy-to-use technique to evaluate vegetable oils quality and authenticity. The spectral range of the middle infrared region (MIR) of FTIR spectra, from 4000 to 600 cm−1, has been commonly used to fingerprint specific functional groups of lipids and their modified forms induced by oxidation of thermal treatment. The applicability of FTIR-MIR spectroscopy in assessing oil fingerprinting and quality parameters is crucially dependent on the chemometric methods, including calibrations with authentic samples. We report here the evaluation of seven types of cold-pressed functional oils (sunflower, pumpkin, hempseed, soybean, walnut, linseed, sea buckthorn) produced in Romania, provided directly from small enterprises (as genuine, process-controlled authentic samples) comparative to commercialized samples. Concomitantly, olive oils of similar claimed quality were investigated. The ATR-FTIR-MIR data were complemented by UV–Vis spectral fingerprints and multivariate analysis using Unscrambler X.10.4 and Metaboanalyst 4.0 software (e.g., PCA, PLSDA, cluster analysis, heatmap, Random forest analysis) and ANOVA post-hoc analysis using Fischer’s least significant difference. The integration of spectral and chemometric analysis proved to offer valuable criteria for their botanical group recognition, individual authenticity, and quality, easy to be applied for large cohorts of commercialized oils.
Carmen Socaciu; Florinela Fetea; Floricuta Ranga; Andrea Bunea; Francisc Dulf; Sonia Socaci; Adela Pintea. Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (ATR-FTIR) Coupled with Chemometrics, to Control the Botanical Authenticity and Quality of Cold-Pressed Functional Oils Commercialized in Romania. Applied Sciences 2020, 10, 8695 .
AMA StyleCarmen Socaciu, Florinela Fetea, Floricuta Ranga, Andrea Bunea, Francisc Dulf, Sonia Socaci, Adela Pintea. Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (ATR-FTIR) Coupled with Chemometrics, to Control the Botanical Authenticity and Quality of Cold-Pressed Functional Oils Commercialized in Romania. Applied Sciences. 2020; 10 (23):8695.
Chicago/Turabian StyleCarmen Socaciu; Florinela Fetea; Floricuta Ranga; Andrea Bunea; Francisc Dulf; Sonia Socaci; Adela Pintea. 2020. "Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (ATR-FTIR) Coupled with Chemometrics, to Control the Botanical Authenticity and Quality of Cold-Pressed Functional Oils Commercialized in Romania." Applied Sciences 10, no. 23: 8695.
Natural products black cumin—Nigella sativa (N. sativa) and wild garlic—Allium ursinum (AU) are known for their potential role in reducing cardiovascular risk factors, including antracycline chemotherapy. Therefore, this study investigates the effect of N. sativa and AU water and methanolic extracts in a cellular model of doxorubicin (doxo)-induced cardiotoxicity. The extracts were characterized using Ultraviolet-visible (UV-VIS) spectroscopy, Fourier-transform infrared (FT-IR) spectroscopy, Liquid Chromatography coupled with Mass Spectrometry (LC-MS) and Gas Chromatography coupled with Mass Spectrometry (GC-MS) techniques. Antioxidant activity was evaluated on H9c2 cells. Cytosolic and mitochondrial reactive oxygen species (ROS) release was evaluated using 2′,7′-dichlorofluorescin-diacetate (DHCF-DA) and mitochondria-targeted superoxide indicator (MitoSOX red), respectively. Mitochondrial membrane depolarization was evaluated by flow cytometry. LC-MS analysis identified 12 and 10 phenolic compounds in NSS and AU extracts, respectively, with flavonols as predominant compounds. FT-IR analysis identified the presence of carbohydrates, amino acids and lipids in both plants. GC-MS identified the sulfur compounds in the AU water extract. N. sativa seeds (NSS) methanolic extract had the highest antioxidant activity reducing both intracellular and mitochondrial ROS release. All extracts (excepting AU methanolic extract) preserved H9c2 cells viability. None of the investigated plants affected the mitochondrial membrane depolarization. N. sativa and AU are important sources of bioactive compounds with increased antioxidant activities, requiring different extraction solvents to obtain the pharmacological effects.
Raluca Maria Pop; Ioana Corina Bocsan; Anca Dana Buzoianu; Veronica Sanda Chedea; Sonia Ancuța Socaci; Michela Pecoraro; Ada Popolo. Evaluation of the Antioxidant Activity of Nigella sativa L. and Allium ursinum Extracts in a Cellular Model of Doxorubicin-Induced Cardiotoxicity. Molecules 2020, 25, 5259 .
AMA StyleRaluca Maria Pop, Ioana Corina Bocsan, Anca Dana Buzoianu, Veronica Sanda Chedea, Sonia Ancuța Socaci, Michela Pecoraro, Ada Popolo. Evaluation of the Antioxidant Activity of Nigella sativa L. and Allium ursinum Extracts in a Cellular Model of Doxorubicin-Induced Cardiotoxicity. Molecules. 2020; 25 (22):5259.
Chicago/Turabian StyleRaluca Maria Pop; Ioana Corina Bocsan; Anca Dana Buzoianu; Veronica Sanda Chedea; Sonia Ancuța Socaci; Michela Pecoraro; Ada Popolo. 2020. "Evaluation of the Antioxidant Activity of Nigella sativa L. and Allium ursinum Extracts in a Cellular Model of Doxorubicin-Induced Cardiotoxicity." Molecules 25, no. 22: 5259.
Lavender flowers were used in this study as a source of phytochemicals as naturally occurring antioxidants. Two different extraction techniques were applied, such as ultrasound-assisted (UAE) and supercritical fluids (SCE) methods. The comparative evaluation of the phytochemicals profile evidenced a higher content of chlorophyll a and b of 5.22 ± 0.12 mg/g (dry weight (D.W.) and 2.95 ± 0.16 mg/g D.W, whereas the carotenoids content was 18.24 ± 0.04 mg/g D.W. in the SCE extract. Seven main compounds were found in both extracts: β-linalool, eucalyptol, linalool acetate, β-trans-ocimene, and limonene in SCE and linalool acetate, β-linalool, 6-methyl-2-(2-oxiranyl)-5-hepten-2-ol, linalool oxide, lavandulyl acetate and camphor in UAE. The (n-3) acids had a higher contribution in SCE. The extracts were microencapsulated in different combinations of wall materials based on polysaccharides and milk proteins. The four variants showed different phytochemical and morphological profiles, with a better encapsulating efficiency for proteins (up to 98%), but with a higher content of encapsulated carotenoids for polysaccharides, the latter showing remarkable antimicrobial activity against selected microorganisms. Carboxymethyl cellulose and whey proteins led to a double encapsulation of lipophilic compounds. The powders were tested in two food matrices as ingredients, with multiple targeted functions, such as flavoring, antimicrobial, antioxidant activity that can successfully replace synthetic additives.
Simona (Lupoae); Liliana Mihalcea; Iuliana Aprodu; Sonia Socaci; Mihaela Cotârleț; Elena Enachi; Oana Crăciunescu; Vasilica Barbu; Anca Oancea; Francisc Dulf; Petru Alexe; Gabriela Bahrim; Gabriela Râpeanu; Nicoleta Stănciuc. Fostering Lavender as a Source for Valuable Bioactives for Food and Pharmaceutical Applications through Extraction and Microencapsulation. Molecules 2020, 25, 5001 .
AMA StyleSimona (Lupoae), Liliana Mihalcea, Iuliana Aprodu, Sonia Socaci, Mihaela Cotârleț, Elena Enachi, Oana Crăciunescu, Vasilica Barbu, Anca Oancea, Francisc Dulf, Petru Alexe, Gabriela Bahrim, Gabriela Râpeanu, Nicoleta Stănciuc. Fostering Lavender as a Source for Valuable Bioactives for Food and Pharmaceutical Applications through Extraction and Microencapsulation. Molecules. 2020; 25 (21):5001.
Chicago/Turabian StyleSimona (Lupoae); Liliana Mihalcea; Iuliana Aprodu; Sonia Socaci; Mihaela Cotârleț; Elena Enachi; Oana Crăciunescu; Vasilica Barbu; Anca Oancea; Francisc Dulf; Petru Alexe; Gabriela Bahrim; Gabriela Râpeanu; Nicoleta Stănciuc. 2020. "Fostering Lavender as a Source for Valuable Bioactives for Food and Pharmaceutical Applications through Extraction and Microencapsulation." Molecules 25, no. 21: 5001.
Nowadays, one of the most important research directions that concerns the scientific world is to exploit the earth’s resources in a sustainable way. Considering the increasing interest in finding new sources of bioactive molecules and functional products, many research studies focused their interest on demonstrating the sustainability of exploiting marine macroalgal biomass as feedstock for wastewater treatment and natural fertilizer, conversion into green biofuels, active ingredients in pharmaceutical and nutraceutical products, or even for the production of functional ingredients and integration in the human food chain. The objective of the present paper was to provide an overview on the recent progress in the exploitation of different macroalgae species as a source of bioactive compounds, mainly emphasizing the latter published data regarding their potential bioactivities, health benefits, and industrial applications.
Elena-Suzana Biris-Dorhoi; Delia Michiu; Carmen Pop; Ancuta Rotar; Maria Tofana; Oana Pop; Sonia Socaci; Anca Farcas. Macroalgae—A Sustainable Source of Chemical Compounds with Biological Activities. Nutrients 2020, 12, 3085 .
AMA StyleElena-Suzana Biris-Dorhoi, Delia Michiu, Carmen Pop, Ancuta Rotar, Maria Tofana, Oana Pop, Sonia Socaci, Anca Farcas. Macroalgae—A Sustainable Source of Chemical Compounds with Biological Activities. Nutrients. 2020; 12 (10):3085.
Chicago/Turabian StyleElena-Suzana Biris-Dorhoi; Delia Michiu; Carmen Pop; Ancuta Rotar; Maria Tofana; Oana Pop; Sonia Socaci; Anca Farcas. 2020. "Macroalgae—A Sustainable Source of Chemical Compounds with Biological Activities." Nutrients 12, no. 10: 3085.
Nigella sativa (NS) has been used for centuries in various inflammatory conditions because of its anti-inflammatory and antioxidant activities. The study aimed to evaluate the anti-inflammatory, antinociceptive and antioxidant activity of Nigella sativa oil (NSO) in two models of acute (carrageenan-induced) and sub-acute inflammation (complete Freund’s adjuvant induced) in rats. Materials and Methods: NSO was administered orally 1, 2 and 4 mL/kg in the acute phase. For subacute phase, NSO was administered 4 mL/kg, 7 days before or after inflammation induction, or in association with diclofenac 5 mg/kg. Results: The gas chromatography coupled with mass spectroscopy (GC-MS) analysis showed that NSO is an important source of bioactive compounds, especially p-cymene and thymoquinone. In the acute phase, 1.5 h after administration, NSO (2 and 4 mL/kg) determined an anti-inflammatory effect comparable with that of diclofenac. In the sub-acute administration, NSO had no anti-inflammatory effect. The analgesic effect of NSO was observed only in the sub-acute inflammation in the analgesy-meter test. NSO as treatment proved its antioxidant effect through the reduction of malondialdehyde (MDA) and oxidized glutathione (GSSG), and increases in hydrogen donor capacity (DH) compared to the control group, but the effect was not as intense as that of diclofenac. Conclusion: The present study has proven inconstant anti-inflammatory, analgesic and antioxidative properties of NSO.
Raluca Maria Pop; Octavia Sabin; Șoimița Suciu; Stefan Cristian Vesa; Sonia Ancuța Socaci; Veronica Sanda Chedea; Ioana Corina Bocsan; Anca Dana Buzoianu. Nigella Sativa’s Anti-Inflammatory and Antioxidative Effects in Experimental Inflammation. Antioxidants 2020, 9, 921 .
AMA StyleRaluca Maria Pop, Octavia Sabin, Șoimița Suciu, Stefan Cristian Vesa, Sonia Ancuța Socaci, Veronica Sanda Chedea, Ioana Corina Bocsan, Anca Dana Buzoianu. Nigella Sativa’s Anti-Inflammatory and Antioxidative Effects in Experimental Inflammation. Antioxidants. 2020; 9 (10):921.
Chicago/Turabian StyleRaluca Maria Pop; Octavia Sabin; Șoimița Suciu; Stefan Cristian Vesa; Sonia Ancuța Socaci; Veronica Sanda Chedea; Ioana Corina Bocsan; Anca Dana Buzoianu. 2020. "Nigella Sativa’s Anti-Inflammatory and Antioxidative Effects in Experimental Inflammation." Antioxidants 9, no. 10: 921.
The effects of heat treatment and the addition of tarragon essential oil on physical and mechanical properties of films prepared with 5% whey protein isolate (WPI) and 5% glycerol were investigated in this study. Heat treatment of the film-forming solution caused increases in thickness, moisture content, swelling degree, water vapor permeability (WVP), b*-value, ΔE*-value, transmittance values in the 200–300-nm region, transparency, and puncture resistance of the film, but decreases in water solubility, L*-value, a*-value, transmittance values in the 350–800-nm region, and puncture deformation. When incorporated with tarragon essential oil, heat-treated films have the potential to be used as antimicrobial food packaging. The addition of tarragon essential oil in film-forming solution caused increases in moisture content, solubility in water, WVP, a*-value, b*-value, ΔE*-value, and transparency of the film; decreases in transmittance values in the range of 600–800 nm; and variations in swelling degree, L*-value, transmittance values in the range of 300–550 nm, puncture resistance, and puncture deformation. Nevertheless, different tendencies were noticed in UNT (untreated) and HT (heat-treated) films with regards to transparency, light transmittance, puncture resistance, and puncture deformation. Based on these findings, HT films show improved physical and mechanical properties and, therefore, are more suitable for food-packaging applications.
Maria-Ioana Socaciu; Melinda Fogarasi; Cristina Anamaria Semeniuc; Sonia Ancuţa Socaci; Mihaela Ancuţa Rotar; Vlad Mureşan; Oana Lelia Pop; Dan Cristian Vodnar. Formulation and Characterization of Antimicrobial Edible Films Based on Whey Protein Isolate and Tarragon Essential Oil. Polymers 2020, 12, 1748 .
AMA StyleMaria-Ioana Socaciu, Melinda Fogarasi, Cristina Anamaria Semeniuc, Sonia Ancuţa Socaci, Mihaela Ancuţa Rotar, Vlad Mureşan, Oana Lelia Pop, Dan Cristian Vodnar. Formulation and Characterization of Antimicrobial Edible Films Based on Whey Protein Isolate and Tarragon Essential Oil. Polymers. 2020; 12 (8):1748.
Chicago/Turabian StyleMaria-Ioana Socaciu; Melinda Fogarasi; Cristina Anamaria Semeniuc; Sonia Ancuţa Socaci; Mihaela Ancuţa Rotar; Vlad Mureşan; Oana Lelia Pop; Dan Cristian Vodnar. 2020. "Formulation and Characterization of Antimicrobial Edible Films Based on Whey Protein Isolate and Tarragon Essential Oil." Polymers 12, no. 8: 1748.
This paper aims to assess the biological responses of Lavandula angustifolia Mill. to beech and spruce bark crude extract application. Thus, the biological activity of bark extracts was assessed by determining the germination capacity, biomass production, histo-anatomical aspects and photo-assimilatory pigment accumulation, and by quantitative and qualitative volatile compounds analysis. The application of spruce bark extract (500 mg dry bark/100 mL solvent) resulted in a better development of the leaf tissue and an increase in foliar biomass. We observed the stimulating effect of photo-assimilating pigments accumulation, for all experimental variants, compared to the control. Also, the amount of volatile oil was significantly higher in the treated plants with spruce bark extract (500 mg dry bark/100 mL solvent). Some volatile compounds (cyclen, borneol, cryptone, santalen, and caryophyllene oxide β—farnesene) were identified only in the experimental variants. Also, in the experimental variants, an increase in the quantity of limonene, linalyl acetate and lavandulol was observed. These preliminary results showed that the beech and spruce bark extracts can have biological activities and influence the production of volatile oil in Lavandula angustifolia, causing significant changes in the phytochemical profile of the essential oil. Thus, forest waste bark extracts could be recommended as natural bioregulators in lavender crops.
Corneliu Tanase; Ruxandra Ștefănescu; Béla Darkó; Daniela Lucia Muntean; Anca Corina Fărcaş; Sonia Ancuţa Socaci. Biochemical and Histo-Anatomical Responses of Lavandula angustifolia Mill. to Spruce and Beech Bark Extracts Application. Plants 2020, 9, 859 .
AMA StyleCorneliu Tanase, Ruxandra Ștefănescu, Béla Darkó, Daniela Lucia Muntean, Anca Corina Fărcaş, Sonia Ancuţa Socaci. Biochemical and Histo-Anatomical Responses of Lavandula angustifolia Mill. to Spruce and Beech Bark Extracts Application. Plants. 2020; 9 (7):859.
Chicago/Turabian StyleCorneliu Tanase; Ruxandra Ștefănescu; Béla Darkó; Daniela Lucia Muntean; Anca Corina Fărcaş; Sonia Ancuţa Socaci. 2020. "Biochemical and Histo-Anatomical Responses of Lavandula angustifolia Mill. to Spruce and Beech Bark Extracts Application." Plants 9, no. 7: 859.
Iron deficiency in the human body is a global issue with an impact on more than two billion individuals worldwide. The most important functions ensured by adequate amounts of iron in the body are related to transport and storage of oxygen, electron transfer, mediation of oxidation-reduction reactions, synthesis of hormones, the replication of DNA, cell cycle restoration and control, fixation of nitrogen, and antioxidant effects. In the case of iron deficiency, even marginal insufficiencies may impair the proper functionality of the human body. On the other hand, an excess in iron concentration has a major impact on the gut microbiota composition. There are several non-genetic causes that lead to iron deficiencies, and thus, several approaches in their treatment. The most common methods are related to food fortifications and supplements. In this review, following a summary of iron metabolism and its health implications, we analyzed the scientific literature for the influence of iron fortification and supplementation on the gut microbiome and the effect of probiotics, prebiotics, and/or synbiotics in iron absorption and availability for the organism.
Ioana Gabriela Rusu; Ramona Suharoschi; Dan Cristian Vodnar; Carmen Rodica Pop; Sonia Ancuța Socaci; Romana Vulturar; Magdalena Istrati; Ioana Moroșan; Anca Corina Fărcaș; Andreea Diana Kerezsi; Carmen Ioana Mureșan; Oana Lelia Pop. Iron Supplementation Influence on the Gut Microbiota and Probiotic Intake Effect in Iron Deficiency—A Literature-Based Review. Nutrients 2020, 12, 1993 .
AMA StyleIoana Gabriela Rusu, Ramona Suharoschi, Dan Cristian Vodnar, Carmen Rodica Pop, Sonia Ancuța Socaci, Romana Vulturar, Magdalena Istrati, Ioana Moroșan, Anca Corina Fărcaș, Andreea Diana Kerezsi, Carmen Ioana Mureșan, Oana Lelia Pop. Iron Supplementation Influence on the Gut Microbiota and Probiotic Intake Effect in Iron Deficiency—A Literature-Based Review. Nutrients. 2020; 12 (7):1993.
Chicago/Turabian StyleIoana Gabriela Rusu; Ramona Suharoschi; Dan Cristian Vodnar; Carmen Rodica Pop; Sonia Ancuța Socaci; Romana Vulturar; Magdalena Istrati; Ioana Moroșan; Anca Corina Fărcaș; Andreea Diana Kerezsi; Carmen Ioana Mureșan; Oana Lelia Pop. 2020. "Iron Supplementation Influence on the Gut Microbiota and Probiotic Intake Effect in Iron Deficiency—A Literature-Based Review." Nutrients 12, no. 7: 1993.
Lipophilic constituents are important for the color and aroma of apricots, but also for their health benefits. In the present study, carotenoids, fatty acids, and volatiles were analyzed in 11 apricot cultivars, from which nine were obtained in Romania. High performance liquid chromatography coupled to a diode array detector with atmospheric pressure chemical ionization and mass spectrometry (HPLC-DAD-APCI-MS methodology applied on unsaponified carotenoid extracts allowed the identification and quantification of 19 compounds. The predominant carotenoids in all cultivars were all-trans-β-carotene and its cis isomers. Lutein was present exclusively in non-esterified form, while β-cryptoxanthin was predominantly esterified, mainly with oleic, palmitic, lauric, and stearic acid. Moreover, β-cryptoxanthin linoleate, linolenate, and stearate were detected for the first time in Harogem cultivar. Variation in carotenoid content and composition was observed, with the highest carotenoid content being recorded in Tudor, Harogem, and Mamaia cultivars. The predominant fatty acids determined by gas chromatography–mass spectrometry (GC-MS) were linoleic (up to 47%), palmitic (up to 32.7%), and linolenic (up to 17.16%), with small variations among cultivars. In-tube extraction technique (ITEX)/GC-MS was applied for profiling the volatiles in apricot fruits and 120 compounds were identified, with terpenoids and esters as the most abundant classes. Principal component analysis (PCA) revealed that the carotenoids and the fatty acids profile can be used for variety authentication and discrimination in apricots.
Adela Pintea; Francisc Vasile Dulf; Andrea Bunea; Sonia Ancuța Socaci; Elena Andreea Pop; Vlăduț-Alexandru Opriță; Daniele Giuffrida; Francesco Cacciola; Giovanni Bartolomeo; Luigi Mondello. Carotenoids, Fatty Acids, and Volatile Compounds in Apricot Cultivars from Romania—A Chemometric Approach. Antioxidants 2020, 9, 562 .
AMA StyleAdela Pintea, Francisc Vasile Dulf, Andrea Bunea, Sonia Ancuța Socaci, Elena Andreea Pop, Vlăduț-Alexandru Opriță, Daniele Giuffrida, Francesco Cacciola, Giovanni Bartolomeo, Luigi Mondello. Carotenoids, Fatty Acids, and Volatile Compounds in Apricot Cultivars from Romania—A Chemometric Approach. Antioxidants. 2020; 9 (7):562.
Chicago/Turabian StyleAdela Pintea; Francisc Vasile Dulf; Andrea Bunea; Sonia Ancuța Socaci; Elena Andreea Pop; Vlăduț-Alexandru Opriță; Daniele Giuffrida; Francesco Cacciola; Giovanni Bartolomeo; Luigi Mondello. 2020. "Carotenoids, Fatty Acids, and Volatile Compounds in Apricot Cultivars from Romania—A Chemometric Approach." Antioxidants 9, no. 7: 562.
The use of bioactive compounds can act in growth stimulation and also influence the biosynthesis of the metabolites in plants. The aim of this paper is to assess the influence of the beech (Fagus sylvatica L.) bark crude extract (BBCE) on the growth and development of sage (Salvia officinalis L.) plants. Special attention was given to the analysis of volatile oil obtained from the sage treated plant. Thus, the biological activity of BBCE was assessed by determining the germination capacity, biomass accumulation, histo-anatomical aspects, and photoassimilatory pigment accumulation, quantitative, and qualitative sage volatile oil analysis. The results show stimulation of the biomass and photoassimilatory pigment accumulation. The mesophyll thickness and the vascular tissue surface are smaller in the treated variants, compared to the control. On the other hand, the amount of volatile oil was significantly higher in the treated plants. In the experimental variants, an increase in the quantity of eucalyptol, camphor, camphene, and α-caryophyllene is observed. The amount of eucalyptol increased in the experimental variant, with about 82%, compared to the control. BBCE could be properly used as natural bioregulators because according to our results seems to improve the yield of the sage crop. The results of this research have the potential to contribute greatly to ecological agricultural production.
Corneliu Tanase; Ruxandra Ștefănescu; Diana Gabriela Gheorghieș; Loredana Dandu; Adrian Nisca; Béla Darkó; Sonia Ancuța Socaci. Effects of Beech Bark Extract in the Sage (Salvia Officinalis L.) Plant Growth and Volatile Oil Profile. Agronomy 2020, 10, 676 .
AMA StyleCorneliu Tanase, Ruxandra Ștefănescu, Diana Gabriela Gheorghieș, Loredana Dandu, Adrian Nisca, Béla Darkó, Sonia Ancuța Socaci. Effects of Beech Bark Extract in the Sage (Salvia Officinalis L.) Plant Growth and Volatile Oil Profile. Agronomy. 2020; 10 (5):676.
Chicago/Turabian StyleCorneliu Tanase; Ruxandra Ștefănescu; Diana Gabriela Gheorghieș; Loredana Dandu; Adrian Nisca; Béla Darkó; Sonia Ancuța Socaci. 2020. "Effects of Beech Bark Extract in the Sage (Salvia Officinalis L.) Plant Growth and Volatile Oil Profile." Agronomy 10, no. 5: 676.
Walnut oilcake is a low-cost by-product of the edible oil industry but at the same time it is a valuable source of dietary fiber, natural antioxidants, and polyunsaturated fatty acids. In the context of health-friendly confectionary food products and to reduce the production cost, the aim of this study was to investigate the effect of walnut oilcake by-product on the quality characteristics and volatile profile of modified macarons. For this purpose, GC-MS and ITEX/GC-MS techniques were used to obtain the fatty acids methyl esters and the volatile profiles; physicochemical analyzes were performed to determine the nutritional characteristics and a nine-point hedonic scale test was performed for the sensory characteristics. The substitution of almond flour with 0%, 10%, 25% and 50% walnut oilcake powder increased the fiber, total phenolic content, and antioxidant capacity. Hedonic scores of the macaron samples made with different percentage of walnut oilcake decreased to additions of over 10%. Moreover, this result is emphasized by Pearson’s correlation parameters indicating as optimal addition for modified macarons, percentages up to 10% of walnut oilcake. This approach could reduce the costs related to the acquisition of the ingredients due to the oilcake price which is 3% of the almonds flour price.
Anamaria Pop; Adriana Păucean; Sonia Ancuța Socaci; Ersilia Alexa; Simona Maria Man; Vlad Mureșan; Maria Simona Chiş; Liana Salanță; Iuliana Popescu; Adina Berbecea; Sevastiţa Muste. Quality Characteristics and Volatile Profile of Macarons Modified with Walnut Oilcake By-Product. Molecules 2020, 25, 2214 .
AMA StyleAnamaria Pop, Adriana Păucean, Sonia Ancuța Socaci, Ersilia Alexa, Simona Maria Man, Vlad Mureșan, Maria Simona Chiş, Liana Salanță, Iuliana Popescu, Adina Berbecea, Sevastiţa Muste. Quality Characteristics and Volatile Profile of Macarons Modified with Walnut Oilcake By-Product. Molecules. 2020; 25 (9):2214.
Chicago/Turabian StyleAnamaria Pop; Adriana Păucean; Sonia Ancuța Socaci; Ersilia Alexa; Simona Maria Man; Vlad Mureșan; Maria Simona Chiş; Liana Salanță; Iuliana Popescu; Adina Berbecea; Sevastiţa Muste. 2020. "Quality Characteristics and Volatile Profile of Macarons Modified with Walnut Oilcake By-Product." Molecules 25, no. 9: 2214.
Solanum chacoense (wild potato) is intensively used in breeding, its biochemical profile and putative human health-related traits being transferred into potato cultivars aimed for consumption. The goal of this study was to evaluate the biochemical profile and the anti-tumor potential of methanolic extracts obtained from S. chacoense leaves and tubers against three breast cancer cell lines in comparison to healthy endothelial cells (HUVEC). The biochemical profile of the extracts was determined by HPLC-PDA/-ESI+-MS and ITEX/GC-MS, the selective cytotoxicity by MTT assay whereas RT-qPCR was used to evaluate the expression of proliferation- and apoptosis-related genes. Both extracts proved to be rich in phenolic acids and volatile compounds, the leaf extract also containing glycoalkaloids. Both extracts proved to be cytotoxic for breast cancer cell lines, with IC50 values varying between 132.9 and 390.7 µg/ml. Both extracts had selective cytotoxicity against MCF7 cell line in comparison to HUVECs (selectivity coefficients >2.3). The treatment with the extracts induced overexpression of the pro-apoptotic gene BAX¸ down-regulation of the anti-apoptotic gene BCL-2 and the pro-proliferation genes NFkB, CCND1, and STAT3. Thus S. chacoense extracts proved to be rich in compounds with anticancer proprieties and are capable of inducing selective cytotoxicity on MCF7 cell line.
Daniel Cruceriu; Zorita Diaconeasa; Sonia Socaci; Carmen Socaciu; Ovidiu Balacescu; Elena Rakosy-Tican. Extracts of the Wild Potato Species Solanum chacoense on Breast Cancer Cells: Biochemical Characterization, In Vitro Selective Cytotoxicity and Molecular Effects. Nutrition and Cancer 2020, 73, 630 -641.
AMA StyleDaniel Cruceriu, Zorita Diaconeasa, Sonia Socaci, Carmen Socaciu, Ovidiu Balacescu, Elena Rakosy-Tican. Extracts of the Wild Potato Species Solanum chacoense on Breast Cancer Cells: Biochemical Characterization, In Vitro Selective Cytotoxicity and Molecular Effects. Nutrition and Cancer. 2020; 73 (4):630-641.
Chicago/Turabian StyleDaniel Cruceriu; Zorita Diaconeasa; Sonia Socaci; Carmen Socaciu; Ovidiu Balacescu; Elena Rakosy-Tican. 2020. "Extracts of the Wild Potato Species Solanum chacoense on Breast Cancer Cells: Biochemical Characterization, In Vitro Selective Cytotoxicity and Molecular Effects." Nutrition and Cancer 73, no. 4: 630-641.