Sustainable development of the agro-industrial complex (AIC) requires an integrated assessment of investment activity, production performance, financial returns, and resource provision at the district level. This study evaluates the production and economic performance of 13 districts of the North Kazakhstan Region using a composite scoring approach based on seven groups of indicators: investment activity, gross agricultural output, crop yields, livestock productivity, crop-production profitability, livestock-production profitability, and capital intensity. The information base includes official district-level statistics, materials of the regional agricultural authorities, data on fixed production assets for 2021–2023, and national land-use reporting. The results reveal substantial territorial differentiation. Kyzylzhar and Taiynsha districts form the high-performance group, Esil District is classified above average, whereas Ualikhanov District occupies the lowest position in the aggregate ranking. The analysis also identifies a scale-efficiency mismatch: large agricultural territories do not necessarily demonstrate high profitability or productivity, while several medium-sized districts achieve stronger returns on land and production resources. The findings provide a comparative basis for territorially differentiated agricultural policy, targeted investment support, technological modernization, and the development of processing infrastructure in the North Kazakhstan Region.