This paper presents a fault-tolerant control (FTC) strategy for a six-degree-of-freedom (DoF) anthropomorphic manipulator operating under actuator faults and complex friction dynamics. The proposed framework integrates a backstepping control methodology with LuGre friction modeling and a feedforward neural network (FFNN) for friction estimation. Actuator faults are considered in the form of multiplicative efficiency losses and additive disturbances. An adaptive control law is developed to estimate and compensate for both friction and actuator faults in real time. The stability of the closed-loop system is guaranteed through Lyapunov theory. The simulation results validate the effectiveness and robustness of the proposed approach in ensuring precise trajectory tracking despite faults and friction uncertainties.