Clinical trials are an integral part of the process of developing new drugs, diagnostic methods and medical devices. Clinical trials offer patients the chance to access alternative treatment methods, thereby improving their quality of life, and even achieving recovery. Additionally, clinical trials provide the opportunity for regular contact with a specialist doctor and easier access to diagnostics, ensuring a faster therapeutic path for the patient. One of the key aspects of conducting clinical trials is choosing the right investigator and research center so as to meet specific criteria and guarantee high quality of the conducted studies. Therefore, the aim of the current study was to evaluate the differences between conducting clinical trials in public and commercial centers. A diagnostic survey was used in the study and the research tool chosen was a proprietary questionnaire belonging to the research technique as survey questionnaire. Questionnaires were constructed for the appropriate stakeholders/respondents, namely: doctors and employees of pharmaceutical companies and CROs. The analysis showed that employees of pharmaceutical companies, given the choice, prefer to cooperate with commercial centers. They choose public centers only when they need a center for phase one trials or those requiring hospitalization. The research obtained shows that public centers should improve administrative processes in order to optimize tasks such as contracting or obtaining a study.

Reaction time to a light or sound stimulus is an important element of life. Constructing and testing a measuring device for collecting the response time stimulus focused on two study groups. The results which were obtained showed that people who specialize in sports have 0.15 seconds, better time than people who do not professionally deal with sport. Be tested for both groups with additional verification (stopwatch) confirmed the measuring apparatus along with the application.

Introduction: Chlamydia felis is the main chlamydial pathogen of cats and is associated with conjunctivitis and respiratory disease. This study aimed to estimate the prevalence of Chlamydiaceae and Chlamydia felis , to explore risk factors and predictors (age, sex, breed, origin and ocular signs) for infection using logistic regression, and to appraise genetic diversity via omp A sequencing and phylogenetic analysis. Material and Methods: Conjunctival swabs from 156 cats were examined using real-time PCR assays for Chlamydiaceae and C. felis . Logistic regression and Kaplan–Meier analysis evaluated risk factors, and partial omp A sequences were phylogenetically analysed. Results: Chlamydiaceae DNA was detected in 7.7% (12/156) of cats and was identified as C. felis . Infections were mostly unilateral. Threshold cycle values varied widely, suggesting heterogeneous bacterial loads. Younger age was a significant risk factor, and the probability of infection decreased steadily with age. Ocular signs strongly predicted infection. British Shorthair/Longhair cats had more than threefold higher odds of infection than European Shorthair cats. Phylogenetic analysis of omp A showed very high genome conservation (99.7–100%), which was consistent with global data. Conclusion: This first molecular study of C. felis in Poland in ten years demonstrates that infection mainly affects young, purebred cats with apparent conjunctivitis. The genetic stability of omp A supports the concept of a globally homogeneous C. felis population.