This study presents the metrological validation of encapsulated DS18B20 digital temperature sensors. Eight units were tested, and seven were analysed (sensor 8 was excluded owing to a systematic failure). The evaluation was performed using a standard comparison calibration, where T_ref was defined as the mean of two calibrated Pt-100 probes in a Julabo DYNEO DD 601F thermostatic bath, following the TH-001 procedure of the Spanish Centre of Metrology (CEM). Four validation tests were performed: Test 1 (E1, 20 to 75 °C), Test 2 (E2, 20 to 72 °C), and with an extended range, Test 3 (E3, −12 to 86 °C) and Test 4 (E4, −12 to 86 °C; repetition to assess reproducibility relative to E3), with 10 steady-state readings per setpoint. Erroneous readings were defined and removed (probe 3, Test 4), and set points without valid readings from probe 4 above 68 °C were excluded. Without data processing, the errors were consistent with the manufacturer’s stated ±0.5 °C, despite an inter-probe bias. Several correction models were evaluated (offset, affine linear, polynomial, and segmented); the probe-specific affine linear model provided the best overall compromise, reducing MAE (Mean Absolute Error) to 0.046 to 0.130 °C and RMSE (Root Mean Square Error) to 0.057 to 0.169 °C. The process uncertainty is dominated by the traceability of the Pt-100 probes and the effective nonuniformity of the isothermal volume, which limits the achievable accuracy. The results support the use of individually calibrated DS18B20 sensors for continuous monitoring, provided that the effective operating range is maintained.