Background In the digital age, social media is essential to everyone's life, including medical students. The rapid proliferation and updates in social media make this platform more attractive and accessible. However, online behavior and guidelines have always been a topic of ongoing debate. Thus, the study's objectives were to investigate the usage of social networking sites for various intentions among medical students, their opinions about applying these platforms for educational benefits, and their perception and accountability for e-professionalism. Methodology A cross-sectional study was conducted with the help of an online questionnaire among students of the College of Medicine at King Faisal University, Al-Ahsa, Saudi Arabia, from April to September 2023. Using a convenience sampling method, 577 students were invited to participate, with 97.1% (n = 560) agreeing to take part in the study. Both male and female students from all years, aged between 20 and 24 years, were included in this study. Results Nearly all medical students (99.5%, n = 557) were daily social media users. WhatsApp, YouTube, and Twitter (now X) were the most popular social media platforms, while Facebook was the least used. Gender differences were observed in platform preferences, with females favoring Instagram and Telegram and males preferring Reddit and Discord. Both genders utilize social media for various motives, including enjoyment (78.2%, n = 438), communication (68.4%, n = 383), knowledge (59.6%, n = 334), relaxation (43.6%, n = 244), and e-professionalism (12.5%, n = 70). Remarkably, 89% (n = 500) believed that social media could be a reliable medium for educational activities. Concerning e-professionalism, most students had private social media accounts, and a significant number believed their profiles did not portray them as professionals. However, a majority interacted with faculty members via social media. Male students exhibited a higher sense of e-professionalism responsibility, with many believing that online profiles should be considered during hiring decisions. Besides, female students believed online profiles could influence others' opinions about them. Conclusion Medical students are significantly involved with social media for different reasons. They acknowledge social media's potential benefits and enriching learning experiences. Nevertheless, a student's online behavior and attitude must be cognizant of and allied to the concept of e-professionalism, as it may directly lead to their future growth in medicine.

Objective: Alzheimer disease (AD) is the most common cause of neurodegenerative dementia; it is expected to see global cases tripling by 2050. This study evaluates public awareness of AD in the Eastern region of Saudi Arabia, highlighting the need to improve background knowledge of AD and assess the impact of public education on early detection and management. Methodology: This study was a cross-sectional study that targeted the public in the Eastern region of Saudi Arabia. It was conducted between June 2024 and October 2024. Data were collected using an online questionnaire and analyzed using SPSS software. Results: Our study involved 814 participants. A significant majority (94.7%) believe that brain-stimulating activities can delay AD onset. However, misconceptions persist, with 49.1% incorrectly thinking that AD can affect those in their 30s or 40s, though 86.9% correctly recognize it primarily affects those over 65 years of age. Awareness of cardiovascular health factors as risks was noted by 68.9% of participants, and 60.2% believed environmental toxins could also be a factor. Key recognized symptoms included difficulty in remembering events (76.5%), planning daily activities (65.4%), handling finances (59.7%), and confusion about time and place (79.7%). Furthermore, 80.1% understood that those with AD might better recall older events. The study also found a reliance on informal information sources, with 51.8% of participants guessing answers about the disease. Conclusions: Many participants understand that brain-stimulating activities might delay Alzheimer’s onset, but significant misconceptions regarding its typical age of onset persist. Education programs using reliable sources are crucial for improving community understanding and management of the disease.

Objectives: The current study aimed to determine the awareness and risk factors for diaper dermatitis (DD) in the Eastern Province of Saudi Arabia. Methods: This cross-sectional study utilized an electronic survey, distributed from February to May 2025, among parents through collaboration with local kindergartens to collect information about their children’s diaper use. Results: The study included 441 participants, showing that the main risk factors associated with the disease included age, as children above 24 months had higher frequencies of the disease, as well as the administration of supplementary food and allergies. No significant correlations were found with long-term medication use, congenital malformations, or gastrointestinal infections. Conclusion: Healthcare providers should encourage caregivers not to delay toilet training their children to avoid the risk of DD. In addition, encourage breastfeeding, as those who were administered supplementary foods had a higher risk of the disease.

Drug-induced cutaneous phenotypes can act as early, bedside-visible clinical risk signals of systemic toxicity because the skin externalizes immune dysregulation, epithelial injury, and microvascular disturbance before organ-specific symptoms are obvious. This narrative review synthesizes peer-reviewed human evidence linking drug-related eruptions to systemic harm and actionable clinical decisions. We searched databases through January 2026 with citation chasing and organized findings using a morphology-anchored framework cross mapped to drug classes and mechanisms. High-risk patterns repeatedly signal urgent systemic risk: painful dusky or targetoid lesions with mucosal involvement and blistering/epidermal detachment require immediate culprit withdrawal and admission-level supportive care; widespread eruption with facial edema plus fever, lymphadenopathy, eosinophilia, or atypical lymphocytosis requires drug discontinuation and close monitoring for drug reaction with eosinophilia and systemic symptoms (DRESS). Research priorities include prospective validation of phenotypes as quantitative predictive risk signals, harmonized outcomes, reproducible imaging standards, and bias-aware digital implementation.

This study provide a comprehensive analysis of using oral isotretinoin as a promising therapy for severe to moderate seborrheic dermatitis, which is a chronic inflammatory skin condition that results in scaling as well as erythema that affects specific sites of the skin such as the scalp, face, upper trunk, or flexures. However, the exact cause of this condition is unclear.Various internal and external factors are associated with its pathogenesis. It is believed that the main factor is the overgrowth of Malassezia yeast, which is a part of the normal skin flora,proliferates in the sebum-rich areas.Other causes include host related factors like genetic predisposition, altered inflammatory responses as well as immune dysregulation, caused by conditions such as HIV or malignancies. In addition, neurophysiological and environmental factors can influence the disease onset. Cold climate, stress, and neurological disorders such as Parkinson’s disease all are key factors influencing the onset and relapse of the disease.Pathogenesis involves a complicated interaction between microbial, immunological, and epidermal factors. Malassezia antigens and metabolites in predisposed individuals can trigger both innate and adaptive immunity leading to inflammatory reactions. In addition, Malassezia’s lipase activity damages the skin barrier by.producing unsaturated fatty acids, leading to raised epidermal turnover and scaling.

Background/Objectives: Artificial intelligence (AI) holds significant potential to enhance diagnostic support and access to dermatological care; however, its adoption depends on public trust and acceptance. This study aimed to assess knowledge, attitudes, and acceptance of dermatological AI among Saudi adults, and to identify factors associated with adoption, trust, and preferred system characteristics. Methods: A nationwide cross-sectional online survey was conducted among 668 Saudi adults (≥18 years) between 21 May and 5 June 2025, using convenience and snowball sampling via social media platforms (WhatsApp, Snapchat, Twitter/X, and Telegram). The questionnaire captured demographics, attitudes toward AI (20-item Likert scale), and perceived importance of six AI system features. Data were analyzed using descriptive statistics, one-way ANOVA, and binary logistic regression. The study was approved by the Institutional Review Board of King Faisal University (Approval No. KFU-REC-2025-MAY-ETHICS3443, approval date 19 May 2025). Results: The mean overall AI attitude orientation score was 74.48 ± 10.20 (Cronbach’s α = 0.868), reflecting moderately positive but conditional attitudes toward dermatological AI. Participants strongly preferred physician-supervised AI over fully autonomous systems, with medical oversight receiving the highest agreement (mean 4.27 ± 0.87). Privacy protection and diagnostic accuracy were rated as the most important system features. Age was significantly associated with the overall AI attitude orientation score (p = 0.009), with younger participants demonstrating more favorable orientations. Interest in technology showed the strongest association with both AI attitude orientation and perceived importance (p < 0.001). No demographic variable independently predicted high intention to use AI in multivariate analysis. Conclusions: Saudi adults generally exhibit favorable yet cautious attitudes toward dermatological AI. Implementation strategies should prioritize physician oversight, transparency, data privacy, and culturally responsive design to support responsible integration into clinical practice.