Jakob Hofmann

Mr. Jakob Hofmann


Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
17 March 2026 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
FPFlorian Pachmann
Florian Pachmann
AKAlexander M. Keppler
Alexander M. Keppler
JHJakob Hofmann
Jakob Hofmann
SHSalome Hagelstein
Salome Hagelstein
CLChristopher Lampert
Christopher Lampert
LFLeon Faust
Leon Faust
Background: Early mobilization with permission for full weight bearing is a cornerstone of postoperative care after proximal femoral fractures (PFFs). However, its biomechanical implementation during gait remains unclear. Clinical scores such as the Charlson Comorbidity Index (CCI) and the American Society of Anesthesiologists (ASA) classification describe comorbidity burden, but their relationship with actual weight bearing and functional outcome regarding activities associated with daily living is insufficiently understood. Methods: In this prospective cohort study, patients aged > 65 years treated surgically for femoral neck fractures (FNFs) or trochanteric femoral fractures (TFFs) were included. Postoperative weight bearing was assessed after 4 to 7 days using sensor-based insoles. Average peak force of the operated limb, normalized to body weight, was the primary outcome. Associations with postoperative weight bearing and functional outcome were analyzed using multivariable linear regression models. Results: Early postoperative weight bearing remained below recommended levels, with lower limb loading in TFFs. Higher CCI values were associated with increased loading in TFF patients, and higher ASA classifications with reduced loading. Higher postoperative Barthel Index (BI) was independently associated with increased limb loading. Postoperative BI was influenced by age, preoperative BI, and fracture type. Conclusions: Despite permission for full weight bearing, early postoperative limb loading after PFF remains below recommended levels, particularly in TFFs. CCI and ASA show fracture type-specific associations with actual weight bearing, whereas BI is independent of ASA and CCI. The BI may serve as a surrogate parameter to identify patients at risk of insufficient limb loading who may benefit from targeted physiotherapeutic interventions.