This paper reviews the recent literature on technologies and methodologies for quantitative human gait analysis in the context of neurodegnerative diseases. The use of technological instruments can be of great support in both clinical diagnosis and severity assessment of these pathologies. In this paper, sensors, features and processing methodologies have been reviewed in order to provide a highly consistent work that explores the issues related to gait analysis. First, the phases of the human gait cycle are briefly explained, along with some non-normal gait patterns (gait abnormalities) typical of some neurodegenerative diseases. The work continues with a survey on the publicly available datasets principally used for comparing results. Then the paper reports the most common processing techniques for both feature selection and extraction and for classification and clustering. Finally, a conclusive discussion on current open problems and future directions is outlined.

Parkinson’s is the second most common neurodegenerative disease, affecting nearly 8.5M people and steadily increasing. In this research, Multimodal Deep Learning is investigated for the Prodromal stage detection of Parkinson's Disease (PD), combining different 3D architectures with the novel Excitation Network (EN) and supported by Explainable Artificial Intelligence (XAI) techniques. Utilizing data from the Parkinson’s Progression Markers Initiative, this study introduces a joint co-learning approach for multimodal fusion, enabling end-to-end training of deep neural networks and facilitating the learning of complementary information from both imaging and clinical modalities. DenseNet with EN outperformed other models, showing a substantial increase in accuracy when supplemented with clinical data. XAI methods, such as Integrated Gradients for ResNet and DenseNet, and Attention Heatmaps for Vision Transformer (ViT), revealed that DenseNet focused on brain regions believed to be critical to prodromal pathophysiology, including the right temporal and left pre-frontal areas. Similarly, ViT highlighted the lateral ventricles associated with cognitive decline, indicating their potential in the Prodromal stage. These findings underscore the potential of these regions as early-stage PD biomarkers and showcase the proposed framework's efficacy in predicting subtypes of PD and aiding in early diagnosis, paving the way for innovative diagnostic tools and precision medicine.

The 0-day attack is a cyber-attack based on vulnerabilities that have not yet been published. The detection of anomalous traffic generated by such attacks is vital, as it can represent a critical problem, both in a technical and economic sense, for a smart enterprise as for any system largely dependent on technology. To predict this kind of attack, one solution can be to use unsupervised machine learning approaches, as they guarantee the detection of anomalies regardless of their prior knowledge. It is also essential to identify the anomalous and unknown behaviors that occur within a network in near real-time. Three different approaches have been proposed and benchmarked in exactly the same condition: Deep Autoencoding with GMM and Isolation Forest, Deep Autoencoder with Isolation Forest, and Memory Augmented Deep Autoencoder with Isolation Forest. These approaches are thus the result of combining different unsupervised algorithms. The results show that the addition of the Isolation Forest improves the accuracy values and increases the inference time, although this increase does not represent a relevant problematic factor. This paper also explains the features that the various models consider most important for classifying an event as an attack using the explainable artificial intelligence methodology called Shapley Additive Explanations (SHAP). Experiments were conducted on KDD99, NSL-KDD, and CIC-IDS2017 datasets.

Automatic traffic flow classification is useful to reveal road congestions and accidents. Nowadays, roads and highways are equipped with a huge amount of surveillance cameras, which can be used for real-time vehicle identification, and thus providing traffic flow estimation. This research provides a comparative analysis of state-of-the-art object detectors, visual features, and classification models useful to implement traffic state estimations. More specifically, three different object detectors are compared to identify vehicles. Four machine learning techniques are successively employed to explore five visual features for classification aims. These classic machine learning approaches are compared with the deep learning techniques. This research demonstrates that, when methods and resources are properly implemented and tested, results are very encouraging for both methods, but the deep learning method is the most accurately performing one reaching an accuracy of 99.9% for binary traffic state classification and 98.6% for multiclass classification.