Intensive farming systems on irrigated rice fields tend to decline soil quality. An appropriate combination of fertilizer applications will provide essential nutrients for crops and affect the chemical properties of the soil. Objectives of the study were to investigate the effect of straw management and inorganic fertilizer (NPK) application on soil chemical properties of irrigated rice fields, including pH H 2 O, soil organic carbon (SOC), and cation exchange capacity (CEC). The field experiment was conducted using a Randomized Block Design (RBD) with 10 treatments and three replications. The treatments comprised control (no treatment), fresh straw, decayed straw, straw compost, manure, NPK (Urea, SP-36, and KCl) + fresh straw, NPK + decayed straw, manure, NPK + straw compost, and NPK + manure. As a result, we could not find any difference for pH, SOC, and CEC at 45, 85, and 120 days after transplanting (DAT). However, our block, which represented the position of the terrace, showed a significant effect on all parameters except CEC at 120 DAT. This result indicates that pH, SOC, and CEC within one planting season would be more affected by the environments of the soil rather than the application of straw and inorganic fertilizer. Hence, there is a need to evaluate the long-term effect of straw management and NPK application to determine the effectiveness in changing pH, SOC, and CEC of irrigated rice fields.