Shahzeer Karmali

Dr. Shahzeer Karmali


Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 June 2012 in BMC Health Services Research
Verified
Journal Article
Open access
PDF file
RPRaj Padwal
Raj Padwal
SMSumit R Majumdar
Sumit R Majumdar
SKScott Klarenbach
Scott Klarenbach
DBDaniel W Birch
Daniel W Birch
SKShahzeer Karmali
Shahzeer Karmali
ASArya M. Sharma
Arya M. Sharma
Protracted, multi-year wait times exist for bariatric care in Canada. Our objective was to examine wait-listed patients’ health status and perceptions regarding the consequences of prolonged wait times using a cross-sectional study design nested within a prospective cohort.

28 March 2023 in Obesity Surgery
Verified
Journal Article
Closed access
PDF file
VMValentin Mocanu
Valentin Mocanu
HWHillary Wilson
Hillary Wilson
KVKevin Verhoeff
Kevin Verhoeff
JKJanice Kung
Janice Kung
CWCaolan Walsh
Caolan Walsh
SKShahzeer Karmali
Shahzeer Karmali

30 November 2022 in Nature Reviews Endocrinology
Verified
Journal Article
Closed access
PDF file
CACaroline M. Apovian
Caroline M. Apovian
XGXirong Guo
Xirong Guo
JHJohn Alan Hawley
John Alan Hawley
SKShahzeer Karmali
Shahzeer Karmali
RLRuth J. F. Loos
Ruth J. F. Loos
WWWilma E. Waterlander
Wilma E. Waterlander

Verified
Journal Article
Open access
PDF file
KNKhadija Nasser
Khadija Nasser
SJSukhdeep Jatana
Sukhdeep Jatana
NSNoah J. Switzer
Noah J. Switzer
SKShahzeer Karmali
Shahzeer Karmali
DBDaniel W. Birch
Daniel W. Birch
VMValentin Mocanu
Valentin Mocanu
Background: The adoption of robotic bariatric surgery has increased dramatically over the last decade. While outcomes comparing bariatric and laparoscopic approaches are debated, little is known about patient factors responsible for the growing delivery of robotic surgery. A better understanding of these factors will help guide the planning of bariatric delivery and resource allocation. Methods: Data were extracted from the MBSAQIP registry from 2020 to 2021. The patient population was organized into primary robot-assisted sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) versus those who underwent laparoscopic procedures. Bivariate analysis and multivariable logistic regression modeling were conducted to characterize cohort differences and identify independent patient predictors of robotic selection. Results: Of 318,151, 65,951 (20.7%) underwent robot-assisted surgery. Patients undergoing robotic procedures were older (43.4 ± 11.8 vs. 43.1 ± 11.8; p < 0.001) and had higher body mass index (BMI; 45.4 ± 7.9 vs. 45.0 ± 7.6; p < 0.001). Robotic cases had higher rates of medical comorbidities, including sleep apnea, hyperlipidemia, gastroesophageal reflux disease (GERD), and diabetes mellitus. Robotic cases were more likely to undergo RYGB (27.4% vs. 26.4%; p < 0.001). Robotic patients had higher rates of numerous complications, including bleed, reoperation, and reintervention, resulting in higher serious complication rates on multivariate analysis. Independent predictors of robotic selection included increased BMI (aOR 1.02), female sex (aOR 1.04), GERD (aOR 1.12), metabolic dysfunction, RYGB (aOR 1.08), black racial status (aOR 1.11), and lower albumin (aOR 0.84). Conclusions: After adjusting for comorbidities, patients with greater metabolic comorbidities, black racial status, and those undergoing RYGB were more likely to receive robotic surgery. A more comprehensive understanding of patient factors fueling the adoption of robotic delivery, as well as those expected to benefit most, is needed to better guide healthcare resources as the landscape of bariatric surgery continues to evolve.

22 January 2013 in Journal of Obesity
Verified
Journal Article
Open access
PDF file
JBJohan Bolton
Johan Bolton
RGRichdeep S. Gill
Richdeep S. Gill
AAAkram Al-Jahdali
Akram Al-Jahdali
SBSimon Byrns
Simon Byrns
XSXinzhe Shi
Xinzhe Shi
SKShahzeer Karmali
Shahzeer Karmali
Background. Weight regain secondary to VBG pouch dilation is a typical referral for Bariatric surgeons. In this study we compare an endoluminal pouch reduction (Stomaphyx) to RYGB for revision.Methods. A retrospective review was completed for patients with a previous VBG presenting with weight regain between 2003–2010.Results. Thirty patients were identified for study 23 RYGB, 14 StomaphyX. Significant post procedure BMI loss was seen in each cohort (RYGB,47.7 ± 7 kg/m2to35 ± 7 kg/m2; StomaphyX43 ± 10 kg/m2to40 ± 9 kg/m2,P=0.0007). Whereas nausea and headache were the only complications observed in StomaphyX patients, the RYGB group had a 43.5% complication rate and 1 mortality. Complications following RYGB include: incisional hernia (13%), anastomotic leak (8.7%), respiratory failure (8.7%), fistula (8.7%), and perforation (4.35%). The median length of stay following RYGB was 6 days compared to1.5 ± 0.5days following StomaphyX.Conclusion. This study suggests that while RYGB revision may achieve greater weight loss, the complication rates and severity is discouraging. StomaphyX may be a safe alternative. Further technical modifications of the device and longer follow-up may clarify the role of this approach.

7 July 2023 in Surgeries
Verified
Journal Article
Open access
PDF file
KVKevin Verhoeff
Kevin Verhoeff
VMValentin Mocanu
Valentin Mocanu
Jerry DangJerry Dang
Jerry Dang
DBDaniel W. Birch
Daniel W. Birch
SKShahzeer Karmali
Shahzeer Karmali
NSNoah J. Switzer
Noah J. Switzer
COVID-19 resulted in dramatic changes to the delivery of bariatric surgery; however, the lasting effect on current and future delivery remains uncharacterized. We sought to characterize differences and trends in bariatric surgery care and outcomes between 2020 and 2021. The Metabolic and Bariatric Accreditation and Quality Improvement Program (MBSAQIP) collects data from 902 centers in North America. The MBSAQIP database was evaluated, including patients undergoing sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) with two cohorts described: those receiving surgery in 2020 and those in 2021. Patient selection, operative techniques, and outcomes were compared using bivariate analysis. Multivariable modelling evaluated factors including operative year, independently associated with serious complications and mortality. We evaluated 349,209 patients, with 154,960 (44.4% undergoing bariatric surgery during 2020 compared to 194,249 (55.6%) in 2021. This represents a 20.2% year-to-year increase in total cases, and a 20.7% increase in cases per center (178.5 cases/center in 2020 vs. 215.4 cases/center in 2021). Patients receiving bariatric surgery during 2021 were statistically younger with fewer comorbidities compared to 2020; however, differences were small and groups appeared clinically similar. Length of stay continued to decrease (1.4 ± 1.1 days 2020 vs. 1.3 ± 1.2 days 2021, p < 0.001), yet post-operative outcomes remained similar. Bariatric surgical volumes have increased but may still remain inadequate to meet demand, while trends towards selecting younger, healthier patients for bariatric surgery continue. Efforts to recover from the effects of COVID-19 are ongoing, and long-term evaluation of outcomes following these changes will remain important.