Background/Objectives: Speech disorders caused by neurological, articulatory, cognitive, and behavioral impairments require accurate multimodal analysis frameworks capable of jointly understanding acoustic abnormalities and neurolinguistic inconsistencies for reliable computer-assisted speech disorder assessment. Recent multimodal deep learning approaches have utilized speech signals, linguistic transcripts, attention mechanisms, and contextual fusion strategies to improve disordered speech analysis and intelligent disorder prediction. However, existing methods frequently suffer from insufficient temporal synchronization, ineffective local–global feature learning, multimodal redundancy, poor interpretability, and reduced robustness under heterogeneous speech disorders. To address these challenges, Methods: The proposes NSX-Net (NeuroSpeech Explainable Network), an intelligent multimodal deep learning framework for speech disorder classification using Acoustic Speech Signal Data and Neurolinguistic Text/Linguistic Data. Initially, the Adaptive Speech Refinement Module (ASRM) performs noise removal, silence elimination, signal normalization, spectrogram generation, MFCC extraction, and transcript preprocessing to improve multimodal speech consistency. Subsequently, the Hierarchical Multimodal Feature Learning Unit (HMFLU) extracts discriminative feature representations through the Cross-Domain Representation Encoder (CDRE), Fine-Grained Speech Pattern Analyzer (FGSPA), and Global Sequential Dependency Learner (GSDL) for capturing both local articulation abnormalities and long-range semantic dependencies. Furthermore, the Dual-Path Attention Enhancement Block (DPAEB) emphasizes clinically important disordered speech regions using adaptive local–global attention mechanisms, while the Temporal Resolution Synchronization Module (TRSM) aligns rhythm-level and beat-level multimodal contextual structures to improve temporal consistency and suppress noise disturbances. Results: Experimental evaluation across six publicly available multimodal speech disorder datasets demonstrated that NSX-Net achieved superior performance, with 99.27% Accuracy, 99.11% Precision, 98.97% Recall, 99.02% F1-Score, and 99.41% AUC, significantly outperforming existing state-of-the-art frameworks. Conclusions: Finally, optimized multimodal contextual representations are forwarded into a Softmax classification layer for intelligent multiclass speech disorder prediction with improved interpretability and potential clinical applicability.

Depression is a prevalent mental health disorder characterized by persistent sadness, loss of interest, and impaired daily functioning. Wearable monitoring systems have emerged as promising tools for continuous mental health assessment; however, they face challenges such as data privacy concerns, misclassification risks, and limited ability to capture complex emotional states. To address these limitations, this study proposes a Self-Supervision-Enabled Compounded Multi-Modal Feature-Learning Network (S2-CFL) for depressive state classification using wearable sensor data and psychological self-reports. The framework integrates a Twin-Path Encoder–Decoder Network (TP-EDN) for extracting temporal features from raw signals and a Densely Connected Convolution Pyramidal Transformer Network (DC2-PTN) for learning spatial representations from signal-to-image transformations. A fusion mechanism combines multi-modal features to predict depressive states, valence, and arousal levels, while a Fine-Grained Emotion Classification Network (FGECN) is employed to categorize emotional states into multiple classes using supervised learning models. Experimental results demonstrate that the proposed multi-modal approach improves classification performance and provides interpretable insights into emotional and depressive patterns.