Mustafa Aytek Simsek

Dr. Mustafa Aytek Simsek


Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 January 2018 in Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology
Verified
Journal Article
Open access
MSMustafa Aytek Simsek
Mustafa Aytek Simsek
AYAyd
Ayd
TATa
Ta
DEDe
De
Objective: Bariatric surgery has been shown to improve cardiac structure and function in obese patients. This study was an examination of the short-term effects of sleeve gastrectomy on body measurements and diastolic function. Methods: A total of 41 consecutive obese patients who were scheduled to undergo a sleeve gastrectomy procedure were included in the study. Baseline body and echocardiographic measurements and the follow-up counterpart data, including total and excess weight loss percentages, were recorded. Results: The mean age of the patients was 42.85 +/- 11.47 years. Of the total, 21 (51.1%) patients were female. The mean body mass index (BMI) was 44.86 +/- 5.62 kg/m(2). The mean duration of follow-up was 91.24 +/- 44.48 days. The participants demonstrated statistically significant weight loss (26.64 +/- 10.95 kg), as well as a decrease in BMI (8.84 +/- 3.93 kg/m(2)) and body surface area (0.27 +/- 0.12 m(2)). A significant increase in E velocity and mitral annular e velocity were observed, as well as a significant decrease in A velocity, E/e ratio, left ventricle mass, and left atrial volume (LAV). No significant correlations between the body measurement changes and changes in echocardiographic parameters were observed, with the exception that the excessive weight loss percentage was moderately correlated with a change in LAV. Conclusion: Sleeve gastrectomy led to a significant decrease in body weight and improved diastolic function parameters in the short-term. No significant relationship was found between the amount of weight loss and change in echocardiographic measurements.

5 November 2021 in The Anatolian Journal of Cardiology
Verified
Journal Article
Open access
EAEmre Aslanger
Emre Aslanger
ACAyca Turer Cabbar
Ayca Turer Cabbar
BHBurak Hunuk
Burak Hunuk
MSMustafa Aytek Simsek
Mustafa Aytek Simsek
FDFirat Demircan
Firat Demircan
ITIstanbul- Turkey
Istanbul- Turkey

15 February 2021 in Cardiology
Verified
Journal Article
Closed access
PDF file
MSMustafa Aytek Simsek
Mustafa Aytek Simsek
BKBetül Korkmaz
Betül Korkmaz
AEAdnan Ezici
Adnan Ezici
ACAyca Turer Cabbar
Ayca Turer Cabbar
EAEmre Aslanger
Emre Aslanger
MDMuzaffer Degertekin
Muzaffer Degertekin
Aim: The relationship between heme oxygenase-1 (HO-1) levels and atherosclerosis was investigated in multiple studies. The aim of this study was to establish the relationship between HO-1 levels and coronary SYNergy between percutaneous coronary intervention with TAXus and Cardiac Surgery (SYNTAX) score in patients with stable coronary artery disease (CAD). Methods: Patients who had been planned to undergo invasive coronary angiography due to a suspected CAD, between the dates of September and December 2019, were included in the study. Serum HO-1 levels were measured from peripheral venous blood. The SYNTAX score was calculated using standard coronary angiography images. Regression analysis was performed to establish the relationship between HO-1 levels and the SYNTAX score. Results: In total, 137 patients were included. The median age was 63 years (IQR: 15), and most of the patients were male (75.2%). The median HO-1 level was 1.44 (IQR: 0.88) ng/mL, and the median SYNTAX score was 6 (IQR: 13). Regression analysis showed that HO-1 is the single most important variable associated with the SYNTAX score (HO-1 levels from 1.01 to 1.87 ng/mL, OR: 6.77, 95% confidence interval 5.18–8.36, p < 0.0001). Conclusion: In this study, serum HO-1 levels were significantly associated with the coronary SYNTAX score.

18 March 2022 in Future Cardiology
Verified
Journal Article
Closed access
MSMustafa Aytek Simsek
Mustafa Aytek Simsek
ACAyca Turer Cabbar
Ayca Turer Cabbar
OOOlcay Ozveren
Olcay Ozveren
OTOge Tascilar
Oge Tascilar
MDMuzaffer Degertekin
Muzaffer Degertekin
Background: The authors investigated the relationship between weight loss after sleeve gastrectomy and change in atrial electromechanical delay values. Methods: A total of 41 patients were included... Plain language summary Obesity is associated with heart rhythm disturbances. Synchrony between the electrical and mechanical activities of the heart is adversely affected in people with obesity. In...

31 January 2024
Verified
Preprint
Open access
MSMustafa Aytek Simsek
Mustafa Aytek Simsek
ACAyca Turer Cabbar
Ayca Turer Cabbar
Myocarditis is associated with increased morbidity and mortaity in patients with Covid-19 infection. Little is known about the true nature and exact pathogenesis of myocardial involvement in these patients. 44 year old patient admitted with exertional dyspnea. He had previous coronary artery bypass surgey and received hemodialysis for lupus nephritis. He was diagnosed with Covid-19 infection 1 month ago. Echocardiography revealed decreased left ventricular ejection fraction and left ventricular global longitudinal strain (GLS). Coronary computerized tomographic angiography revealed patent bypass grafts. His medical treatment was adjusted. Follow up echocardiography after 3 months showed markedly improved LVEF and left ventricular GLS.

13 September 2021 in SDÜ Tıp Fakültesi Dergisi
Verified
Journal Article
Open access
ACAyca Turer Cabbar
Ayca Turer Cabbar
MSMustafa Aytek Simsek
Mustafa Aytek Simsek
BHBurak Hünük
Burak Hünük
OÖOlcay Özveren
Olcay Özveren
ÖGÖzge Güzelburç
Özge Güzelburç
MDMuzaffer Değertekin
Muzaffer Değertekin
Objective Since many studies focused on the relationship between mean platelet volume (MPV) and severity of type 2 diabetes mellitus (T2DM) or investigated MPV and coronary artery disease (CAD) mostly on acute coronary syndrome (ACS), this study primarily focused to investigate if MPV values have any relation with different levels of CAD specifically in T2DM patients, who had no previous coronary artery disease, and no ACS history. Materials And Methods T2DM patients who had first coronary angiography (CAG) between November 2019 and February 2020, and whose after night fasting blood tests were performed before CAG were included. Two cardiologists, blinded to the patients, evaluated angiographies. Patients have divided into groups accordingly; normal coronary artery (Group 1), non-critic stenosis (Group II), and severe CAD (Group III) according to the Gensini score. Patients’ demographics, heart rate, risk factors of CAD, and blood test including MPV were also collected. Results A total of 180 patients (88 female, 92 male) were involved in the study. There was no significant relation between MPV and the severity of CAD in T2DM patients (p=0.228). The mean age of the Group I group was significantly lower than in other groups (p=0.228), and there were significantly lower males in Group I than other groups (p=0.0001). The triglycerides levels were significantly low in Group I than in other groups (p=0.021 and p=0.006). Conclusion MPV values were not associated with the severity of CAD in stable patients. Older age, male gender, higher levels of triglycerides, and initial glucose levels were significantly related to the severity of CAD in T2DM patients.