Periodontitis is a chronic disease that begins with a period of inflammation of the supporting tissues of the teeth table and then progresses, destroying the tissues until loss of the teeth occurs. The restoration of the damaged dental support apparatus is an extremely complex process due to the regeneration of the cementum, the periodontal ligament, and the alveolar bone. Conventional treatment relies on synthetic materials that fill defects and replace lost dental tissue, but these approaches are not substitutes for a real regeneration of tissue. To address this, there are several approaches to tissue engineering for regenerative dentistry, among them, the use of stem cells. Mesenchymal stem cells (MSC) can be obtained from various sources of adult tissues, such as bone marrow, adipose tissue, skin, and tissues of the orofacial area. MSC of dental origin, such as those found in the bone marrow, have immunosuppressive and immunotolerant properties, multipotency, high proliferation rates, and the capacity for tissue repair. However, they are poorly used as sources of tissue for therapeutic purposes. Their accessibility makes them an attractive source of mesenchymal stem cells, so this review describes the field of dental stem cell research and proposes a potential mechanism involved in periodontal tissue regeneration induced by dental MSC.

The primary neural processes that help maintain cognitive abilities during aging are neuronal plasticity and compensatory scaffolding. These can be directly promoted through participation in intellectually stimulating activities, without psychological stress, with physical exercise, and a healthy diet. In this context, environmental factors that affect cognition can be classified at three levels: (i) micro-level (family and home): social interaction with family members and indoor pollution; (ii) meso-level (commu-nity and services): the variety of land uses, ease of access, and green spaces; (iii) mac-ro-level (society in general and public policies): social representations of old age and aging (positive aging vs. ageism), and public policies to improve activities related to cognitive maintenance. All three levels are interrelated and are determinants of cogni-tive function in old age. In this sense, the interaction of intrinsic capacity with the en-vironment, linked to behavioral characteristics, determines cognitive functional capac-ity and well-being within the framework of healthy aging. Therefore, the aim of this review is to synthesize information on the effect of the environment on the cognitive functions of older adults, linking biological, environmental and behavioral elements.

Introducción. El sarcoma de Kaposi (SK) es una neoplasia maligna de células endoteliales linfáticas. La principal localización es cutánea y su diagnóstico definitivo se establece mediante un estudio histopatológico. Objetivo. Presentar el estado del arte del conocimiento sobre el sarcoma de Kaposi de tipo epidémico Desarrollo. Existen cuatro tipos clínicos de SK: el clásico, el endémico o africano, el iatrogénico y el epidémico o asociado a VIH (KSHV). Este último, es la neoplasia más frecuentemente asociada al virus de inmunodeficiencia humana (VIH). También se ha asociado al herpes virus humano 8 (HHV-8) y puede ser agente causal del KSHV. Conclusiones. La detección y tratamiento oportuno del KSHV, incrementa la esperanza de vida de los pacientes con VIH. Además, el reconocimiento y las medidas de salud pública pueden reducir su propagación y ayudar a reducir la incidencia del KSHV.

Cognition in older adults may be influenced by environmental factors; however, the pathways linking environmental exposures and cognition remain unclear. The aim of this narrative review is to synthesize evidence on the association between the environment and cognition in older adults, integrating biological, environmental, and behavioral elements. Systematic reviews and original studies addressing this topic were identified in Web of Science, PubMed, and Scopus. The primary neural processes associated with maintaining cognition during aging are neuronal plasticity and compensatory scaffolding. Participation in intellectually stimulating activities, physical exercise, and a healthy diet; mitigation of chronic stress; reduction in the severity of depressive symptoms; and buffering against the adverse effects of air pollution are proposed as plausible pathways that may mediate the relationship between neural processes and the environment. In this context, environmental factors that affect cognition can be classified at three levels: (i) micro-level (family and home): social interaction with family members and indoor pollution; (ii) meso-level (community and services): social interaction, land-use diversity, transportation systems, environmental design, and urban green spaces; and (iii) macro-level (society in general and public policies): social representations of old age and aging (positive aging vs. ageism) and public policies aimed at improving pathways related to cognitive maintenance. Overall, the environment may influence cognition in older adults; however, the available studies show methodological and conceptual heterogeneity, inconsistent findings, and important gaps in knowledge.

Introducción: La periodontitis es una enfermedad que afecta los tejidos de soporte de los dientes. Inicia por una disbiosis a nivel del surco gingival que causa inflamación crónica en el periodonto, por lo cual clínicamente se observa disminución de la inserción clínica, resorción ósea, presencia de bolsas periodontales, movilidad dental y, cuando no es tratada a tiempo, pérdida de los dientes. Dado los estragos que causa a nivel sistémico y en la calidad de vida de quien la padece, se han buscado alternativas que potencialicen el efecto de la terapia convencional, entre estas propuestas está el uso del propóleo. Objetivo: Presentar una síntesis del conocimiento sobre la eficacia del propóleo como tratamiento coadyuvante de periodontitis. Desarrollo: El propóleo es una sustancia resinosa no tóxica producida por las abejas. Posee propiedades antimicrobianas, antifúngicas, antiinflamatorias, antioxidantes y antitumorales. Dado que casi todas las formas de periodontitis incluyen una infección bacteriana, se ha propuesto que el uso de propóleo puede ser útil para su tratamiento. Se han realizado estudios in vitro, in vivo y algunos ensayos clínicos con buenos resultados. La disminución de los signos clínicos de la periodontitis parece estar asociada a la capacidad antioxidante de los flavonoides contenidos en el propóleo y a su efecto antimicrobiano. Conclusión: El propóleo puede ser utilizado como coadyuvante a la terapia convencional de la periodontitis en humanos. Sin embargo, es necesario realizar más estudios para determinar la dosis y la vía de administración.

El libro “Odontología de Mínima Interven¬ción para la atención de Caries Dental en un Modelo de Servicio Estomatológico”, es un texto académico, didáctico, dirigido a los estudiantes de la carrera de Cirujano Dentista, de acceso libre (https://www.za¬ragoza.unam.mx/area-quimico-biologicas/).