PRABHAT GHANSHYAM BHARGAVA

Dr. PRABHAT GHANSHYAM BHARGAVA

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Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 June 2023 in Journal of Gastrointestinal Cancer
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Journal Article
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SGSandeep Gedela
Sandeep Gedela
PMPritesh Munot
Pritesh Munot
AVArvind Vaidyanathan
Arvind Vaidyanathan
RJRitam Joarder
Ritam Joarder
DCDeepali Chaugule
Deepali Chaugule
VOVikas Ostwal
Vikas Ostwal

15 October 2022 in Journal of Gastrointestinal Cancer
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Journal Article
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ARAnant Ramaswamy
Anant Ramaswamy
PBPRABHAT GHANSHYAM BHARGAVA
PRABHAT GHANSHYAM BHARGAVA
SSSujay Srinivas
Sujay Srinivas
SKSadhana Kannan
Sadhana Kannan
Manish BhandareManish Bhandare
Manish Bhandare
VOVikas Ostwal
Vikas Ostwal

5 August 2024 in Annals of Surgical Oncology
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Journal Article
Open access
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KGKaival K. Gundavda
Kaival K. Gundavda
SPShraddha Patkar
Shraddha Patkar
SKSadhana Kannan
Sadhana Kannan
GVGurudutt P. Varty
Gurudutt P. Varty
KNKunal Nandy
Kunal Nandy
MGMahesh Goel
Mahesh Goel
Background: ‘Textbook Outcome’ (TO) represents an effort to define a standardized, composite quality benchmark based on intraoperative and postoperative endpoints. This study aimed to assess the applicability of TO as an outcome measure following liver resection for hepatic neoplasms from a low- to middle-income economy and determine its impact on long-term survival. Based on identified perioperative predictors, we developed and validated a nomogram-based scoring and risk stratification system. Methods: We retrospectively analyzed patients undergoing curative resections for hepatic neoplasms between 2012 and 2023. Rates of TO were assessed over time and factors associated with achieving a TO were evaluated. Using stepwise regression, a prediction nomogram for achieving TO was established based on perioperative risk factors. Results: Of the 1018 consecutive patients who underwent liver resections, a TO was achieved in 64.9% (661/1018). The factor most responsible for not achieving TO was significant post-hepatectomy liver failure (22%). Realization of TO was independently associated with improved overall and disease-free survival. On logistic regression, American Society of Anesthesiologists score of 2 (p = 0.0002), perihilar cholangiocarcinoma (p = 0.011), major hepatectomy (p = 0.0006), blood loss >1500 mL (p = 0.007), and presence of lymphovascular emboli on pathology (p = 0.026) were associated with the non-realization of TO. These independent risk factors were integrated into a nomogram prediction model with the predictive efficiency for TO (area under the curve 75.21%, 95% confidence interval 70.69–79.72%). Conclusion: TO is a realizable outcome measure and should be adopted. We recommend the use of the nomogram proposed as a convenient tool for patient selection and prognosticating outcomes following hepatectomy.

29 December 2023 in Indian Journal of Surgical Oncology
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Journal Article
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BGB. Sree Ganesh
B. Sree Ganesh
Mufaddal KaziMufaddal Kazi
Mufaddal Kazi
MGMahesh Goel
Mahesh Goel
ASAvanish Saklani
Avanish Saklani
ASAshwin De Souza
Ashwin De Souza
SPShraddha Patkar
Shraddha Patkar

13 September 2024 in Annals of Surgical Oncology
Verified
Journal Article
Closed access
PDF file
KGKaival K. Gundavda
Kaival K. Gundavda
SPShraddha Patkar
Shraddha Patkar
SKSadhana Kannan
Sadhana Kannan
GVGurudutt P. Varty
Gurudutt P. Varty
KNKunal Nandy
Kunal Nandy
MGMahesh Goel
Mahesh Goel