Ayşe Nur Topuz

Dr. Ayşe Nur Topuz

orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 September 2021 in Biomarkers in Medicine
Verified
Journal Article
Closed access
ÖŞÖmer Şen
Ömer Şen
SŞSıdıka B Şen
Sıdıka B Şen
ATAyşe Nur Topuz
Ayşe Nur Topuz
MTMustafa Topuz
Mustafa Topuz
Aim: No-reflow phenomenon (NRP) is an undesirable result of coronary interventions, and usually occurred during the primary percutaneous coronary intervention (PPCI). On the other hand, there is gr...

30 September 2022 in Cukurova Medical Journal
Verified
Journal Article
Open access
PDF file
ATAyşe Nur Topuz
Ayşe Nur Topuz
NBNafiz Bozdemi̇r
Nafiz Bozdemi̇r
Purpose: The iam of this study was to assess the cardiovascular knowledge level of an educated and healthy population and determine how much they transferred it to daily life. In the current study, we first determined Cardiovascular Disease (CVD) Risk Factors Knowledge Level and Framingham score and investigated their relationship between pulse wave velocity (PWV) and laboratory parameters of healthy personal working for Cukurova University. Materials and Methods: The study was conducted via 192 participants who were selected from the study sample among healthy personnel working for Cukurova University. All participants' knowledge level was determined with the Cardiovascular Disease Risk Factors Knowledge Level (CARRF-KL) scale and the 10-year risk for development of CVD determined by the Framingham risk score. PWV was also determined non-invasively by using an arteriography device. Blood samples were collected from all participants. Results: The mean age of all participants was 45.3 ± 8.0 years (53.6% woman). The mean CARRF-KL score of the participants was found as 20.4 ± 4.0 and the mean Framingham score was found 6.9±5.6. The average PWV was found 7.9±1.5m/sn. In correlation analyses, PWV was well correlated with both the mean CARRF-KL score and Framingham score. Participants who had the highest CARRF-KL score had also the highest Framingham score and PWV . Conclusion: Despite the high level of education and knowledge, it is seen that this knowledge is not reflected in daily lives in terms of CVD risk factors. Further studies are needed whether there is a threshold level of CVD knowledge that must be attained for knowledge to influence behavior and risk factor levels. For effective prevention, knowledge should be supported by behavioral counseling interventions.

7 August 2019 in The Aging Male
Verified
Journal Article
Closed access
AAAdem Altunkol
Adem Altunkol
ATAyşe Nur Topuz
Ayşe Nur Topuz
ÖGÖmer Genç
Ömer Genç
EAErgün Alma
Ergün Alma
MTMustafa Topuz
Mustafa Topuz
Background: It is well known that erectile dysfunction (ED) is associated with increased risk of atrial fibrillation (AF) development. On the other hand, prolongation of the duration of atrial electromechanical delay (AEMD) is known to be a precursor for AF development. We aimed to evaluate AEMD in patients with ED patients without documented AF. Methods: Total of 68 outpatients with previously documented vascular ED and 44 participants without ED were enrolled to the current study. Sixty-eight patients with ED called as ED group and 44 participants without ED served as control group. We performed International Index of Erectile Function (IIEF-5) questionnaire for all participants to determine the disease severity of ED groups and to diagnose ED in control groups. Patients with a IIEF-5 score ≥22 were defined as having normal erectile functions. Both intra- and inter-AEMD were measured with tissue Doppler imaging. P-wave dispersion (PWD) was measured on a 12-lead electrocardiogram. Results: Basal characteristics were similar between the two groups. PWD, inter- and right intra-AEMD were significantly prolonged in patients with ED, compared to the control group (p = .02, p < .001 and p < .001, respectively). In the correlation analysis, IIEF-5 score was significantly negative correlated with systolic blood pressure, right intra- and inter-AEMD (r = –0.37, p = .02; r= −0.27, p = .02; r = –0.39, p = .001, respectively). Conclusions: According to current study results, AEMD is significantly correlated with ED severity and may be useful to stratify ED patients to the high-risk group for future development of AF as a cheap and easy method.

20 March 2017 in Turkish Journal of Family Medicine and Primary Care
Verified
Journal Article
Closed access
ATAyşe Nur Topuz
Ayşe Nur Topuz
SKSelin Kızılgök
Selin Kızılgök
MSMahir Serbes
Mahir Serbes
NBNafiz Bozdemir
Nafiz Bozdemir

1 April 2026 in Sexual Medicine
Verified
Journal Article
Open access
HAHakan Anıl
Hakan Anıl
AYAli Yıldız
Ali Yıldız
ATAyşe Nur Topuz
Ayşe Nur Topuz
MKMehmet Vehbi Kayra
Mehmet Vehbi Kayra
SSSinan Sözütok
Sinan Sözütok
YBYıldırım Bayazıt
Yıldırım Bayazıt
Background: Erectile dysfunction (ED) is a prevalent condition, with vasculogenic ED being the most common subtype, primarily related to endothelial dysfunction and cardiovascular risk factors. Low-intensity extracorporeal shock wave therapy (Li-ESWT) has emerged as a promising non-invasive treatment option. However, predictors of treatment response remain poorly defined. Aim: To identify clinical and vascular predictors of treatment success following Li-ESWT in patients with vasculogenic ED and to develop a novel, practical, and non-invasive scoring system to predict therapeutic response. Methods: This prospective study included 219 men aged 18-80 years with vasculogenic ED between January 2024 and January 2025. All patients underwent Li-ESWT (18 000 pulses over 3 weeks). Clinical and vascular parameters, including age, ED duration, body mass index, presence of cardiovascular risk factors, diabetes mellitus (DM), carotid intima-media thickness (cIMT), flow-mediated dilation rate (FMD), and prior phosphodiesterase type 5 inhibitor (PDE5i) response, were recorded. Treatment success at 6 months was defined as an increase of ≥1 point in the erection hardness score or ≥5 points in the International Index of Erectile Function-5 EF. Outcomes: The primary outcome was treatment success at 6 months after Li-ESWT. Secondary outcomes included the development and validation of a predictive scoring system. Results: Treatment success rate was 66.2% (145/219). Independent predictors of treatment success were absence of DM (odds ratio [OR] = 2.67, P = .012), ED duration <36 months (OR = 2.23, P = .026), cIMT <0.8 mm (OR = 2.04, P = .042), prior PDE5i benefit (OR = 2.47, P = .016), FMD ≥5% (OR = 2.57, P = .012), age <65 years (OR = 2.28, P = .032), and presence of cardiovascular risk factors (OR = 2.23, P = .036). A scoring system incorporating these 7 variables achieved an area under the curve of 0.819 (95% confidence interval [CI] 0.762-0.877). Using a cut-off of 4.5 points, the sensitivity was 73% and the specificity was 77% (P < .001). Clinical Implications: This scoring system may help clinicians identify patients most likely to benefit from Li-ESWT, optimize patient selection, and improve individualized treatment strategies in vasculogenic ED. Strengths & Limitations: The study is strengthened by its prospective design, relatively large sample size, and inclusion of vascular function parameters (FMD, cIMT). Limitations include the lack of external validation and the absence of penile Doppler ultrasound confirmation in all patients. Conclusion: This study identified key demographic and vascular predictors of Li-ESWT response and introduces a novel, non-invasive clinical scoring system with strong predictive accuracy. This tool may enhance treatment personalization and support clinical decision-making in the management of ED.

3 April 2026 in Psychiatry International
Verified
Journal Article
Open access
PDF file
ZÖZeliha Yelda Özer
Zeliha Yelda Özer
ATAyşe Nur Topuz
Ayşe Nur Topuz
İÜİlker Ünal
İlker Ünal
HKHatice Kurdak
Hatice Kurdak
SÖSevgi Özcan
Sevgi Özcan
We aimed to investigate factors associated with post-earthquake coping strategies and to examine the relationship between coping styles and post-traumatic stress disorder (PTSD) symptom levels. This multicenter cross-sectional study was conducted among individuals presenting to 22 primary health centers in the Adana and Osmaniye provinces of Türkiye between 13 and 17 March 2023. Data were collected using a structured sociodemographic form, the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), and the Coping with Earthquake Stress Scale. The mean age of the participants (n = 434) was 38.27 ± 13.84 years, and 63.4% were female. The prevalence of probable PTSD was 32.95%. A weak negative correlation was found between PCL-5 scores and positive reappraisal scores (r = −0.192, p < 0.01), whereas no significant associations were observed between PTSD symptom scores and other coping strategies. Positive reappraisal scores were positively correlated with both religious coping (r = 0.248) and seeking social support (r = 0.316) (p < 0.01). Individuals who experienced family-related losses reported higher religious coping scores. These findings suggest that positive reappraisal may be associated with lower PTSD symptom levels in the early post-disaster period, highlighting the potential importance of adaptive cognitive coping strategies in primary care settings.