Hemangioma is a relatively common benign proliferation of blood vessels that primarily develops during childhood. Two main forms of hemangioma recognized: capillary and cavernous. The capillary form presents as a flat area consisting of numerous small capillaries. Cavernous hemangioma appears as an elevated lesion of a deep red color, and consists of large dilated sinuses filled with blood. The purpose of the study was to report the case of a capillary hemangioma in a patient and to describe the successful treatment of this case.
1 December 2021 in Meandros Medical and Dental Journal
Background: This study was performed to determine the therapeutic effects of diosgenin (DG) which is a steroidal saponin, administered at different doses on alveolar bone loss (ABL) in rats with experimental periodontitis using immunohistochemical and cone-beam computed tomography (CBCT).Methods: Thirty-two male Wistar rats divided into four equal groups: control (non-ligated), periodontitis (P), DG-48, and DG-96. Sutures were placed at the gingival margin of the lower first molars to induce experimental periodontitis. Then, 48 and 96 mg/kg of DG was administered to the study groups by oral gavage for 29 days. At day 30, the animals were sacrificed and ABL was determined via CBCT. The expression patterns of osteocalcin (OCN), alkaline phosphatase (ALP), type I collagen (Col-1), B cell lymphoma 2 (Bcl 2), Bcl 2-associated X protein (Bax), bone morphogenetic protein 2 (BMP-2), and receptor activator of NF κB ligand (RANKL) were examined immunohistochemically.Results: Histopathologic examination showed all features of the advanced lesion in the P group. DG use decreased all these pathologic changes. It was observed that periodontitis pathology decreased as the dose increased. DG treatment increased the ALP, OCN, Bcl 2, Col-1, and BMP-2 levels in a dose-dependent manner, compared with the P group (p < 0.05). DG decreased the expression of RANKL and Bax in a dose-dependent manner (p < 0.05). ABL was significantly lower in the DG-48 and DG-96 groups than in the P group (p < 0.05).Conclusion: Collectively, our findings suggest that DG administration protects rats from periodontal tissue damage with a dose-dependent manner, provides an increase in markers of bone formation, decreases in Bax/Bcl-2 ratio and osteoclast activation.
30 March 2023 in Engineering Science and Technology, an International Journal
Covid-19, which threatens human health worldwide, affects people not only emotionally, but also by exposing them to necessary changes in their social behaviors and lifestyles. Psychological health and daily life habits have been transformed by the COVID-19 pandemic. Closure of universities, suspension of clinical training, and transition to online education are likely to affect students negatively. This paper focuses on the stress levels and daily lifestyle changes of students because of the pandemic. A total of 601 participants of dentistry faculty, including 402 preclinical (PC) and 199 intorn (INT) students, filled an online survey questionnaire including sociodemographic data form, “Health-promoting Lifestyle Profile-II (HPLP-II)” form, and “Perceived Stress Scale-10 (PSS-10)” form. IBM SPSS version 25.0. program was used for statistical analyses. HPLP-II and PSS-10 mean scores of PC and INT students were found as moderate. It was determined that variables as gender, educational grade, financial status, living with a relative who is at risk of contracting COVID-19 or having a relative who has the disease caused difference in HPLP-II and PSS-10 total mean score and the average score in the majority of subscales. The current study's findings reveal that COVID-19 pandemic has devastating effects on students' stress levels and lifestyle routines. It is vital to provide services to individuals in order to sustain healthy lifestyle behaviors in order to protect communal health.
30 March 2022 in Clinical and Experimental Health Sciences
Objective: The aim of the study was to compare the salivary IgA and gingival crevicular fluid IgA levels in caries active and caries free subjects. Methods: The study was carried out on 40 subjects divided into two groups, Group I caries free, (DMFT =0) and Group II caries active, (DMFT >10). Saliva and gingival crevicular fluid samples were obtained and plaque index, gingival index, gingival crevicular fluid volume and salivary flow rate were determined. The levels of S. mutans and lactobacillus were determined by culture. IgA concentrations of saliva and gingival crevicular fluid samples were determined using the ELISA. Data were analyzed using the Mann-Whitney U and χ2 tests (α = 0.05). Results: Gingival crevicular fluid volume, plaque index and gingival index values of group II were significantly higher than group I (p< 0.05). Although lactobacillus counts of group II were higher than group I, no statistically significant differences were observed for microorganism counts (p>0.05). Salivary flow rate, gingival crevicular fluid-IgA and saliva-IgA levels were no statistically significant between the groups (p>0.05). Conclusion: The present study showed that microorganism counts in the saliva did not by themselves influence the DMFT index. There is no dependence between secretory immunity and dental caries in subjects.