Objective: The primary objective of our study was to evaluate the predictive performance of serum inflammatory markers and the semi-quantitative computed tomography severity scoring system on diagnosing the Covid 2019 disease and its course. Methods: Our study is a single-center retrospective cohort study. The data of 213 adults who were confirmed to have coronavirus disease 2019 by polymerase chain reaction tests in the period between April 2020 and August 2020 were evaluated. One hundred eighty four of these patients whose C-reactive protein, d-dimer, and ferritin levels, lymphocyte counts, and thoracic computed tomography images were obtained at the time of admission were included in the study. The semi-quantitative computed tomography severity score was calculated for all patients. Results: The median age of the 184 patients included in the study was 51.5 (19-91) years. The incidence of intensive care need and mortality was 10.3% (n = 19) and 5.4% (n = 10), respectively. The intensive care need and mortality rate was significantly correlated with higher thoracic computed tomography involvement scores at admission. There was a statistically significant and positive correlation between the computed tomography scores and the C-reactive protein, d-dimer, and ferritin levels. Older age (> 65 years-old) and thoracic computed tomography scores of 11 and higher were independent factors correlated with need for intensive care. Conclusion: Serum inflammatory markers and semi-quantitative computed tomography severity scoring system were predictive in diagnosing the Covid 2019 disease and its course.
Pes planus is a common postural deformity related to the medial longitudinal arch of the foot. Radiographic examinations are important for reproducibility and objectivity; the most commonly used methods are the calcaneal inclusion angle and Mery angle. However, there may be variations in radiographic measurements due to human error and inexperience. In this study, a deep learning (DL)-based solution is proposed to solve this problem. Lateral radiographs of the right and left foot of 289 patients were taken and saved. The study population is a homogeneous group in terms of age and gender, and does not provide sufficient heterogeneity to represent the general population. These radiography (X-ray) images were measured by 2 different experts and the measurements were recorded. According to these measurements, each X-ray image is labeled as pes planus or non-pes planus. These images were then filtered and resized using Gaussian blurring and median filtering methods. As a result of these processes, 2 separate data sets were created. Generally accepted DL models (AlexNet, GoogleNet, SqueezeNet) were reconstructed to classify these images. The 2-category (pes planus/no pes planus) data in the 2 preprocessed and resized datasets were classified by fine-tuning these reconstructed transfer learning networks. The GoogleNet and SqueezeNet models achieved 100% accuracy, while AlexNet achieved 92.98% accuracy. These results show that the predictions of the models and the measurements of expert radiologists overlap to a large extent. DL-based diagnostic methods can be used as a decision support system in the diagnosis of pes planus. DL algorithms enhance the consistency of the diagnostic process by reducing measurement variations between different observers. DL systems accelerate diagnosis by automatically performing angle measurements from X-ray images, which is particularly beneficial in busy clinical settings by saving time. DL models integrated with smartphone cameras can facilitate the diagnosis of pes planus and serve as a screening tool, especially in regions with limited access to healthcare.
Objective: Symptomatic gastrointestinal metastases are observed in only about 2% of patients with malignant melanoma. We aim to present a case of jejunal perforation secondary to metastatic melanoma. Case: A 64-year-old patient with known metastatic malignant melanoma (involving the brain, liver, and lungs) presented to the emergency department with bowel obstruction symptoms. Abdominal computed tomography (CT) revealed jejunal perforation with significant wall thickening. The patient underwent segmental bowel resection and jejunojejunostomy and was discharged after a one-week hospital stay. Conclusions: Although small bowel metastases from malignant melanoma are relatively common, bowel perforation due to metastasis is extremely rare. Perforation should be considered in the differential diagnosis of acute abdomen in patients with malignant melanoma.
16 September 2025 in Journal of Health Sciences and Medicine
Aims: To evaluate the diagnostic success of thyroid fine needle aspiration biopsy (FNAB) across different age and gender groups, and to investigate the effect of aging and sex-related variables on biopsy adequacy. Methods: This retrospective study included 486 patients who underwent thyroid FNAB between 2022 and 2024. Patients were stratified into two age groups (
Aim: To compare the efficacy and safety of ultrasound-guided microwave ablation (MWA) and combined ethanol plus microwave ablation (EA+MWA) in patients with symptomatic benign thyroid nodules.Materials and Methods: This retrospective study included 24 patients (25 nodules) treated between January 2023 and January 2025. Patients with predominantly solid nodules underwent MWA (n = 18), while patients with nodules with prominent cystic components received EA+MWA (n = 6). Nodule volumes were calculated using the ellipsoid formula before and 6 months after the procedure, and the volume reduction ratio (VRR%) was determined.Results: The mean VRR at 6 months was 62.15% ± 9.61 in the MWA group and 74.37% ± 14.27 in the EA+MWA group. Although higher in the EA+MWA group, the difference did not reach statistical significance (p = 0.094). Both groups demonstrated substantial volume reduction and were free from major complications. Transient hoarseness occurred in four patients.Conclusion: Both MWA and EA+MWA are effective and safe for the treatment of symptomatic benign thyroid nodules. The combination of EA and MWA may provide greater volume reduction in nodules with prominent cystic components.