Automated Fiber Placement (AFP) enables precise deposition of thermoplastic tapes on complex geometries, however variations in temperature, compaction pressure, deposition speed, and tooling conditions can affect the final laminate quality. This study presents an integrated real-time monitoring system and a systematic methodology for process/product data analysis linking process parameters to mechanical and microstructural performance. Mechanical testing evaluation by interlaminar shear strength (ILSS), thermal analysis, and microscopy studies identified both the consolidation and mold temperatures as the critical parameters for optimized mechanical properties. Results showed ILSS above 45 MPa, crystallinity up to 37.9%, and minimal porosity (~1%). Digital tools developed provided full traceability, early instability detection, and continuous optimization, enhancing reliability and repeatability in high-performance thermoplastic composite manufacturing, which paves the way towards zero-defect manufacturing.