Objectives: Parenchymal stiffness obtained by point shear-wave elastography (pSWE) in solid organs is used as a sign of damage in these organs. However, its clinical use and whether patients with polycystic ovary syndrome (PCOS) have increased ovarian tissue stiffness are still unclear. The aim of this study is to determine the parameters related to ovarian stiffness and whether there is an increase in ovarian stiffness in patients with PCOS compared with healthy controls. Methods: Forty-five women who were followed up regularly with the diagnosis of PCOS and 30 healthy controls similar to age and sex were included in this study. In addition to the routine follow-up parameters for PCOS, serum homeostatic model assessment of insulin resistance and anti-Mullerian hormone (AMH) levels were examined in all patients, and pSWE examination was performed with pelvic ultrasound (US) and ElastPQ technique. Results: Serum dehydroepiandrosterone sulfate, luteinizing hormone/follicle-stimulating hormone, testosterone, homeostatic model assessment of insulin resistance, and AMH were higher in PCOS compared with healthy controls (P < 0.001). Right, left, and mean ovary stiffness and volumes were significantly higher in PCOS group than healthy controls (P < 0.001). Correlation analysis was performed between mean ovary stiffness and dehydroepiandrosterone sulfate, luteinizing hormone/follicle-stimulating hormone, testosterone, homeostatic model assessment, and AMH and ovary volumes (P < 0.01 for each one). In linear regression analysis, only AMH was found to be related to mean ovary stiffness (P < 0.001 and β = 0.734). Conclusions: Ovarian stiffness value obtained by ElastPQ technique and pSWE method increases in PCOS patients compared with healthy controls and is closely related to serum AMH levels. In patients with PCOS, in addition to the conventional US, ovarian stiffness measured by pSWE may be an auxiliary examination in the follow-up of the disease. However, it was concluded that the ovarian stiffness measurement obtained in our current study should be supported by studies involving more patients and the transvaginal US method.

Amaç: Bu üç yıllık çalışmamızda acil servisimize başvuran kuduz riskli temas olgularının demografik özelliklerini değerlendirmeyi amaçladık.Gereç ve Yöntem: 2012-2014 yılları arasında kuduz riskli temas nedeniyle acil servisimize başvuran hastaların demografik özellikleri hastane otomasyon sistemi, acil hasta bakı kartları ve kuduz bildirim defterinden geriye dönük olarak incelendi. Elde edilen verilerin istatistiksel analizinde SPSS 21.0 paket programı kullanıldı.Bulgular: Çalışmaya 2732 hasta dâhil edildi. Hastaların %70,4’ü (n:1923) erkek, %29,6’sı (n:809) kadın ve ortalama yaşı 23,65 yıl (min: 0, maks: 87 yıl) idi. Hastaların %15,7’sinin 2012 yılında, %39,3’ünün 2013 yılında, %44,9’unun ise 2014 yılı içinde acil servise başvurduğu belirlendi. Başvurular en sık mayıs, haziran ve temmuz aylarında idi. En sık kuduz şüphesi olan hastalarda köpeklerle (%61,6) ve ısırılma yoluyla (%71,8) temas öyküsü mevcuttu. Hastaların %95,5’ine yara bakımı ve tetanoz profilaksisi uygulanmıştır. Hastaların %99,9’una 1 doz, %85,6’sına 2 doz, %51,5’ine 3 doz, %9,9’una 4 doz ve %6,2’sine 5 doz aşı, %7,9’una kuduz aşısıyla birlikte HRIG yapıldığı saptandı. Hayvanların %99,7’sinin takip süresince yaşadığı, %0,3’ünün ise öldüğü tespit edildi. Hiçbir hastamızda kuduz hastalığı belirtileri ve ölüm görülmedi.Sonuç: Bu çalışma ile kuduz şüpheli hayvanla temasın her geçen yıl artış gösterdiği ve ilimiz için halen ciddi bir halk sağlığı sorunu olduğu belirlendi. Belediyelerce yürütülen sahipsiz hayvan toplama, kontrol ve ıslah hizmetlerine daha fazla önem verilmesi, hayvan barınaklarının kapasite ve sayılarının arttırılması, toplumun kuduz hastalığı açısından bilgilendirilmesi gerekmektedir.

Background: To the best of our knowledge, there are studies related to QT and QTc interval in patients with hypocalcemia, but there are no studies evaluating T wave peak and end interval (Tp-e interval), Tp-e/QT and Tp-e/QTc ratios used to evaluate cardiac arrhythmia risk and ventricular repolarization changes rates. Objectives: Therefore, we aimed to investigate whether there is a change in Tp-e interval, Tp-e/QT and Tp-e/QTc ratios in patients with hypocalcemia. Methods: Retrospectively, 29 patients with hypocalcemia in the [...] Abstract Background: To the best of our knowledge, there are studies related to QT and QTc interval in patients with hypocalcemia, but there are no studies evaluating T wave peak and end interval (Tp-e interval), Tp-e/QT and Tp-e/QTc ratios used to evaluate cardiac arrhythmia risk and ventricular repolarization changes rates. Objectives: Therefore, we aimed to investigate whether there is a change in Tp-e interval, Tp-e/QT and Tp-e/QTc ratios in patients with hypocalcemia. Methods: Retrospectively, 29 patients with hypocalcemia in the