Dr. Cristina Cecchi

1991: Graduated in Biological Sciences; 1995: Specialist in Biochemistry and Clinical Chemistry; 2001: Acquired a PhD Degree in Biochemistry; 2001: Held a Researcher position in Biochemistry at the Faculty of Medicine and Surgery of the University of Florence; 2015: Became an Associate Professor at the Department of Biomedical, Experimental and Clinical Sciences. The research of lab exploits cellular and molecular approaches to investigate the mechanisms by which protein misfolded aggregtaes cause cell dysfunction. The main ongoing research projects include: -The pathogenesis of Alzheimers disease and amiotrophic lateral sclerosis; -The relationship between structure and toxicity of protein oligomers; -The protective role of molecular chaperones against oligomer toxicity; -The protective role of glutathione thioesters against oligomer-induced oxidative stress; -The effect of membrane lipid components, such as GM1 and cholesterol, on oligomer toxicity.