Objective: In general, chemical plaque agents have been used in mouthwashes, gels, and dentifrices. In some situations, application of mouthwashes and dentifrices can be difficult. Therefore, different approaches for oral health-care have been needed. The aim of this study was to evaluate the effect of propolis chewing-gum compared to propolis-containing mouthwash on gingival inflammation and plaque accumulation on patients that refrained from daily oral hygiene procedures for 5 days. Materials and Methods: 10 college students with systemically healthy and very good oral hygiene and gingival health were included in this randomized, single-blind, crossover 5-day plaque regrowth with a 3-day washout period clinical study. After plaque scores were reduced to zero, participants were asked to refrain from oral hygiene procedures and allocated to either propolis mouthwash or chewing-gum group. Chewing-gum was performed after meals 3 times a day for 20 min mouthwash group was instructed to rinse mouthwash 2 times a day for 1 min. On day 5, the clinical periodontal measurements containing plaque and gingival indexes were taken from the participants. Results: The both plaque and gingival indexes of propolis mouthwash group were significantly lower than that of the propolis chewing-gum group (P = 0.005). Conclusion: It was demonstrated that the propolis mouthwash was more effective than the propolis chewing gum on the plaque inhibition and the gingival inflammation.

This study evaluates the effect of polyvinylpyrrolidone sodium hyaluronate gel (Gelclair^®) on palatal wound healing, pain, and bleeding following free gingival graft surgery (FGG). Thirty-two patients undergoing FGG were randomly assigned to two groups: the test group received Gelclair^® and chlorhexidine mouthwash, while the control group received only chlorhexidine. Patients were called at first, third, seventh, fourteenth and twenty-eighth postoperative days and, Visual Analog Scale (VAS), Wound Healing Index (WHI), hydrogen peroxide (H₂O₂) bubbling scores and bleeding situations were recorded. The Friedman test was used for repeated measures, with the Wilcoxon signed-rank test as post-hoc, and the Mann-Whitney U test for between-group comparisons. H₂O₂ test values significantly decreased and WHI values significantly increased over time in both groups (p < 0.050). Test and control groups comparison at time points showed the test group showed significantly lower H₂O₂ test values on days 7, 14, and 28 (p < 0.050) and higher WHI values on days 3, 7, 14, and 28 compared to control group. VAS pain, chewing, and burning scores were also significantly lower in the test group on days 1, 3, 7, and 14 compared to control. While on day 1, the control group had a bleeding rate of 105 times higher than the test group (p < 0.001), no significant differences were observed on days 3 and 7. The findings suggest that Gelclair^® promotes wound healing and reduces discomfort and bleeding in the palatal donor area after FGG. NCT06610331; Retrospectively registered on 23/09/2024.

Aims: This study aimed to evaluate dental students’ perceptions regarding the provision of oral hygiene education (OHE) to patients and to investigate the association between clinical experience and OHE-related perceptions.Methods: This cross-sectional descriptive survey study included fourth and fifth-year students from the Faculty of Dentistry at Bolu Abant İzzet Baysal University. Data were collected using a structured questionnaire designed to assess demographic characteristics, clinical experience, perceived importance of OHE, self-efficacy in providing OHE, perceived barriers, clinical practice frequency, post-graduation intentions, and the perceived effect of clinical experience on OHE. Pearson Chi-square, Fisher’s exact, and multiple Chi-square tests were used for statistical analysis, with a significance level set at p

Background: It is now well known that periodontitis increases the risk of future cardiovascular disease, regardless of well-known risk factors for cardiovascular disease. The aim of this study is to investigate the effect of folic acid (FA) supplementation on endothelial damage caused by periodontitis.Materials and methods: 48 rats were divided randomly into five groups: healthy control (HC), sham control (SC), lipopolysaccharide-induced periodontitis (LPS), lipopolysaccharide-induced periodontitis with low-dose FA (4 mg/kg) (LPS+4), and high-dose FA (12 mg/kg) (LPS+12) administered groups. Rats were euthanized after 15 days of the first lipopolysaccharide injection. Circulating progenitor cells taken from each rat's blood samples were counted using flow cytometry. ADMA, CD34+, and CD133+ expression in periodontal and cardiac tissues were labeled by using immunoperoxidase method.Results: There were no differences among the groups regarding ADMA expression in periodontal tissues. However, the CD34+ and CD133+ expression values reached the highest value in the LPS group, significantly higher than in the healthy group. In the heart tissue, all biomarkers were statistically significant among groups. Flow cytometry analysis results did not differ in ADMA expression level, but CD34+ and CD133+ expression levels were statistically significant between groups. Conclusions: The results of our study showed that periodontitis increases the expression levels of endothelial biomarkers, and FA supplementation positively impacts the endothelium dysfunction caused by periodontitis.