Objective: Urethral stricture is characterized by fibrosis that decreases urine flow. Metabolic syndrome is a complex disorder that causes fibrosis in many organs. This study aimed to evaluate the relationship between metabolic syndrome and appearance of urethral stricture and effects of metabolic syndrome on the recurrence of urethral stricture in patients with primary urethral stricture who underwent direct visual internal urethrotomy. Materials and methods: One hundred thirty-two male patients who underwent direct visual internal urethrotomy between 2014 and 2021 because of primary urethral stricture were included. Location, length, and type of urethral stricture, time from diagnosis to surgery, postoperative follow-up, time from surgery to recurrence, and postoperative follow-up duration with a urethral catheter were retrospectively analyzed and association with metabolic syndrome was evaluated. Results: The mean age was 50.48 ± 17.94 years. Recurrence was found in 34.1% and metabolic syndrome in 27.3%. Postoperative follow-up duration was significantly longer in patients with recurrence than in those without (P=.033). There was no statistically significant difference in terms of metabolic syndrome and postoperative urethral catheterization between patients with and without recurrence (P=.126, P=.714, respectively). Postoperative clean intermittent self-catheterization use was found to be statistically higher in patients with recurrence than in patients without recurrence (P=.018). Postoperative urinary tract infection rate was found to be significantly higher in patients with metabolic syndrome compared to patients without metabolic syndrome (P=.001). Conclusion: Metabolic syndrome was not associated with recurrence. However, postoperative urinary tract infections were more common in patients with metabolic syndrome than in patients without. Clean intermittent self-catheterization used postoperatively may increase the risk of stricture. Cite this article as: Asfuroglu A, Balci M, Koseoglu B, et al. Male urethral stricture in patients with metabolic syndrome. Urol Res Pract., 2023;49(2):131-137.

Objective: This study aimed to determine whether the Mayo adhesive probability (MAP) score could predict perioperative outcomes in transperitoneal laparoscopic total adrenalectomy (LTA) and laparoscopic partial adrenalectomy (LPA). Materials and Methods: The clinical data of 139 patients who underwent transperitoneal LTA (n=116) or LPA (n=23) between March 2013 and September 2022 were retrospectively analyzed. According to the images obtained from preoperative contrast-enhanced computed tomography or magnetic resonance imaging, the patients were divided into two groups: the low MAP score group (0-1 points) and the high MAP score group (2-5 points). General clinical features and perioperative outcomes were compared between the groups. Results: In patients with a high MAP score, the mean body mass index (BMI) (p: 0.005), tumor size (p: 0.005), operative time (p: 0.002), estimated blood loss (EBL) (p: 0.001), and complication rate (p: 0.013) were significantly higher compared to those with a low MAP score. The comparison of the patients between the LTA and LPA subgroups revealed that operative time and EBL were significantly higher in both subgroups among the patients with a high MAP score. Moreover, the complication rate in the LTA subgroup was significantly higher in the high MAP score group compared to the other group. The Multivariate analyses revealed that a high MAP score was a risk factor for prolonged operative time (Odds Ratio [OR]: 3.081, 95% Confidence Interval [CI]: 1.284-7.398, p: 0.012), increased EBL (OR: 2.495, 95% CI: 1.114-5.588, p: 0.026) and complications (OR: 6.085, 95% CI: 1.532-24.171, p: 0.01) Conclusion: Patients with a high MAP score had a prolonged operative time, increased EBL, and a higher complication rate compared to those with a low MAP score. In addition, we found that a high MAP score was an independent risk factor for perioperative parameters and complications in patients who underwent LTA and LPA.

Background: The aim of this study is to compare the clinical outcomes of cystoscopy and laser resectoscope used during transurethral cystolithotripsy (TUC) and to evaluate the efficacy and reliability of these two endoscopic instruments. Materials and Methods: This study included patients who underwent transurethral bladder stone (BS) surgery between 2022 and 2025. Patients were categorized into cystoscope and laser resectoscope groups according to the endoscopic instrument used. Lithotripsy was performed using a holmium laser in all cases. Demographic characteristics, stone-related parameters, perioperative variables, and clinical outcomes were analyzed comparatively. Statistical analyses were performed using appropriate tests, and a p value 0.05). Operation and lithotripsy times were significantly shorter in the laser resectoscope group (29 vs. 45 min; 18 vs. 23 min, respectively; p<0.001). Stone visualization quality was higher in this group, and mucosal bleeding was significantly less frequent (p=0.014). No significant differences were observed regarding hospital stay, catheterization duration, or overall complication rates. Conclusion: Comparable stone-free and safety outcomes were achieved with TUC performed using either a cystoscope or a laser resectoscope. However, the laser resectoscope provided shorter operative times, improved visualization, and reduced mucosal injury, indicating that it is an effective and reliable alternative for TUC.

Objective: Benign prostatic hyperplasia is a common cause of lower urinary tract symptoms (LUTS) in aging men. While transurethral resection of the prostate (TURP) is the traditional surgical standard, holmium laser enucleation of the prostate (HoLEP) has emerged as a safe and effective alternative. Evidence comparing both techniques in small prostates (<50 mL) remains limited. Methods: This retrospective study included male patients aged 40-80 years who underwent bipolar TURP (B-TURP) or HoLEP between 2023 and 2025 for LUTS refractory to medical therapy, with prostate volume .05). Holmium laser enucleation of the prostate showed longer operative time, greater irrigation use, and higher resected tissue weight/percentage (P = .03, .02, <.001, <.001), while hospital stay and catheterization were shorter (both P < .001). Both procedures improved Qmax and IPSS and reduced PVR (all P < .001); the increase in Qmax was greater in HoLEP (P = .025). Conclusion: Both B-TURP and HoLEP are safe and effective for small prostates; however, HoLEP offers advantages in resected tissue weight, Qmax improvement, and shorter hospital stay/catheterization. Cite this article as: G.lbaşı A, Elmaağa. B, Bi.er H, .zercan AY, Günal S, Keske M. Holmium laser enucleation of the prostate vs. bipolar transurethral resection of the prostate for small-volume prostates: A comparative analysis of clinical outcomes. Urol Res Pract. 2025;51(6):225-229.