Hangping Chen

Dr. Hangping Chen


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 May 2024 in Separations
Verified
Journal Article
Open access
PDF file
Ahmad AliAhmad Ali
Ahmad Ali
HCHangping Chen
Hangping Chen
HXHe Xu
He Xu
SWShuo Wang
Shuo Wang
Yao ShunYao Shun
Yao Shun
Plants serve as reservoirs of bioactive compounds endowed by nature, rendering them promising subjects for investigating chemical diversity. Despite their potential, much remains untapped, whether in standardized extracts or isolated pure compounds. This unexplored terrain has paved the way for significant discoveries in pharmaceuticals. Notably, research has delved into the medicinal properties of Mallotus philippensis, a prominent plant in South Asia. Employing meticulous extraction techniques such as maceration, the fruit of this plant underwent initial antimicrobial screening, revealing encouraging results. Subsequent fractionation of the plant’s extracts via liquid–liquid extractions, utilizing dichloromethane and absolute ethanol, facilitated further analysis. Evaluating these fractions for antibacterial activity demonstrated efficacy against various pathogenic microorganisms, particularly Pseudomonas aeruginosa and Escherichia coli, notably by the ethanolic and dichloromethane extracts. Furthermore, a comprehensive phytochemical analysis unveiled the presence of alkaloids, flavonoids, saponins, glycosides, phenols, and tannins. An assessment of the extracts’ antioxidant potential via the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay showcased significant activity, with a radical scavenging rate of 97%. This underscores the significance of utilizing fruit remnants, which are often rich in valuable chemical constituents yet commonly discarded, thereby adding value to both the species and the environment. Further investigation focused on the composition of Mallotus philippensis fruit, encompassing volatile and non-volatile metabolites through HPLC-MS analysis. Additionally, this study introduced the application of ionic liquid-loaded polysulfone microcapsules to enrich target constituents from crude extracts. An exploration of the key separation conditions, results, and recycling performance of these microcapsules provided insights for future research endeavors. Overall, this comprehensive study of Mallotus philippensis fruit extracts establishes a foundation for the ongoing exploration and development of this medicinal plant.

15 June 2023 in Separations
Verified
Journal Article
Open access
PDF file
YGYingying Guo
Yingying Guo
NLNa Liu
Na Liu
HCHangping Chen
Hangping Chen
Ahmad AliAhmad Ali
Ahmad Ali
STSara Toufouki
Sara Toufouki
Yao ShunYao Shun
Yao Shun
With the development of health service, animal husbandry, aquaculture and the chemical industry, more and more pollutants are discharged into the water environment, including antibiotics and heavy-metal ions. These hazardous substances pose a great threat to environmental safety and human health. Two new kinds of green solvents, ionic liquids (ILs) and deep eutectic solvents (DESs), are widely utilized in various fields, including separation and environmental engineering, and are attracting much attention from academia and industry. In this study, an optimal ionic liquid and a deep eutectic solvent were selected, and their complex with β-cyclodextrin (β-CD) was first prepared by a process of simple and effective inclusion. After necessary characterization and analysis, two kinds of complexes were applied to prepare a special two-sided sorbent disc by adding a diluent (excipient) and pressing the substance under 5~15 MPa. As a result, the IL and DES were stably immobilized on the disc to play a key role in the selective adsorption of targets. Moreover, the experiments with different hazardous substances achieved the expected results. This study demonstrates that the complex disc, with its easy preparation, good stability, and simple operation, exhibited many merits in its separation performance. We believe it to be a useful tool for water purification and detection of noxious substances.

19 May 2023 in Preprints.org
Verified
Preprint
Open access
PDF file
YGYingying Guo
Yingying Guo
NLNa Liu
Na Liu
HCHangping Chen
Hangping Chen
Ahmad AliAhmad Ali
Ahmad Ali
STSara Toufouki
Sara Toufouki
Yao ShunYao Shun
Yao Shun
With the development of health service, animal husbandry, aquaculture and chemical industry, more and more pollutants are discharged into the water environment, including antibiotics and heavy metal ions. These hazard substances pose a great threat to environment safety and human health. As two kinds of new green solvents, ionic liquids (ILs) and deep eutectic solvents (DESs) are widely used in various fields including separation and environmental engineering, which are attracting huge attention from academia and industry. In this study, the optimal ionic liquid and deep eutectic solvent were selected and their complex with β-cyclodextrin (β-CD) were firstly prepared by simple and effective inclusion way. After necessary characterization and analysis, two kinds of complex were applied to prepare a special sorbent disc with two different sides by adding diluent (excipient) and pressing under 5~15 MPa. As the result, the IL and DES could be stably immobilized on the disc and play the key role in selective adsorption for targets. Besides that, the experiments of different hazardous substances achieved the expected results. Based on this study, the complex disc showed a lot of merits in the separation performance, easy preparation and use, simple operation, and good stability. It was believed to be a useful tool for water purification and detection.

30 November 2023 in Engineering Proceedings
Verified
Conference Paper
Open access
PDF file
GZGaojin Zhou
Gaojin Zhou
HCHangping Chen
Hangping Chen
RLRuoheng Li
Ruoheng Li
YCYu Cao
Yu Cao
Yao ShunYao Shun
Yao Shun
As a new sustainable catalyst and green solvent, ionic liquid has important applications in catalytic reduction. In this study, four quinuclidinol-based quaternary ammonium ionic liquids (ILs)were at first prepared using simple procedures, and then they were used as catalyst for acetophenone reduction. The main catalytic conditions were studied and screened through a comparison among the reaction results. It showed that the highest yield of 1-phenylethanol was 88.6% when [MenQu]Cl was used as a catalyst; the ideal solvent was ethanol; the amount of catalyst was 20 mol%, and the reaction temperature was 25 °C. More substrates were employed to validate the universality of the developed method using such an IL. Moreover, potential reaction mechanisms and an IL recovery method were also suggested, which laid the foundation for its further applications in the field of sustainable chemistry and cleaner industrial production.