Exercise‐induced hypoalgesia (EIH) is characterized as the pain reduction after an exercise session and it seems to be related to the release of plasma β‐endorphin. In this sense, the core stabilization training (CT) has been suggested for patients with chronic nonspecific low back pain (CNSLBP), but it is unclear whether it induces EIH. Patients with CNSLBP have neuromotor dysfunctions that can affect the performance of functional tasks, thus, performing functional training (FT) could improve motor control and promote EIH, since functional training uses multi‐joint exercises that aim to improve the functionality of actions performed in daily life. EIH is usually assessed using quantitative sensory tests (QST) such as conditioned pain modulation, pressure pain threshold, and temporal summation. Thus, the sum of parameters from quantitative sensory tests and plasma β‐endorphin would make it possible to understand what the neuroendocrine effects of FT and CT session are. Our study compared the acute effect of CT and FT on the EIH and plasma β‐endorphin release, and correlated plasma β‐endorphin with quantitative sensory testing in patients with CNSLBP. Eighteen women performed two training sessions (CT and FT) with an interval of 48 h between sessions. EIH was assessed by QST and plasma β‐endorphin levels. Results showed that only FT significantly increased plasma β‐endorphin (FT p < 0.01; CT p = 0.45), which correlated with pain pressure threshold (PPT) and conditioned pain modulation (CPM). However, QST values were not different in women with CNSLBP after CT or FT protocols. Plasma β‐endorphin correlated with PPT and CPM, however, the same did not occur with a temporal summation.

Desafios no processo de inclusão de alunos com deficiência ainda são vivenciados atualmente. Nesse sentido, a identificação de problemas e potenciais intervenções para a melhoria do ensino e acesso à educação são fundamentais. O presente trabalho teve como objetivo explanar sobre os desafios da educação inclusiva em instituições de ensino do Brasil e investigar quais atitudes didático pedagógicas estão sendo implantadas no país. Foi realizada uma revisão integrativa de literatura com análise descritiva e abordagem qualitativa de artigos publicados no período entre os anos 2000 e 2020. Foram incluídos artigos indexados nas bases de dados Scientific Eletronic Library On-Line–SCIELO, Portal de periódicos da CAPES e Literatura Latino-Americana e do Caribe em Ciências da Saúde–LILACS. No geral, 18 artigos obedeceram a todos os critérios de inclusão e serviram de base para a extração das informações para análise. Como resultado constatou-se que professores e instituições de ensino apresentam falta de capacitação para lidar com alunos com deficiência. Dentre os problemas e dificuldades mais relatados destacou-se o despreparo dos professores, falta de metodologias pedagógicas específicas e carência em estrutura física adequadas nas escolas. Como estratégias para a melhoria do processo de inclusão, destacou-se o uso de jogos. Espera-se que este estudo sirva como mecanismo de reflexão e sensibilização para todos os agentes envolvidos na inclusão de alunos com deficiência e que contribua na adequação e aprimoramento de políticas públicas em prol da qualificação de professores, bem como na adequação das instituições de ensino no Brasil.

Parasitologia na perspectiva da Saúde Única (978-65-5941-182-5) - Investigação Sorológica Da Leishmaniose Felina Em Abrigo De Animais De Área Endêmica Para A Doença No Nordeste Do Brasil Utilizando A Proteína Rkddr-Plus

Most Leishmania infantum infected dogs remain healthy, with low parasitic loads and negative to low antibody levels, making detection challenging. rKDDR-plus has shown outstanding diagnostic performance in ELISA but has never been tested in dogs thoroughly characterized by physical examination and routine laboratory tests. This study aimed to evaluate the diagnostic performance of rKDDR-plus ELISA in dogs with different L. infantum infection states (n = 94), classified as healthy seronegative (n = 25), healthy seropositive (n = 54), and sick (n = 15). In total, 37 seropositive dogs were classified as low and 32 as high. Diagnostic performance was evaluated in five groups: (G1) all dogs, (G2) healthy seronegative + sick (n = 40), (G3) healthy seronegative + healthy seropositive (n = 79), (G4) healthy seronegative + high seropositive (n = 57), and (G5) healthy seronegative + low seropositive (n = 62). Negative percent agreement was 100% in all groups, while positive percent agreement was perfect in G2 (100%), followed by G4 (96.88%), G1 (82.61%), G3 (77.78%), and G5 (70.27%). Accuracy ranged from 85.14% to 100%, and the area under the ROC curve (AUC-ROC) was as follows: G2 (1.000), G4 (0.978), G1 (0.951), G3 (0.937), and G5 (0.928). Agreement (kappa) was almost perfect in G2 and G4, and substantial in the remaining groups. In conclusion, rKDDR-plus ELISA shows overall good diagnostic performance.