Wearable textile chemical sensors are promising devices due to the potential applications in medicine, sports activities and occupational safety and health. Reaching the maturity required for commercialization is a technology challenge that mainly involves material science because these sensors should be adapted to flexible and light-weight substrates to preserve the comfort of the wearer. Conductive polymers (CPs) are a fascinating solution to meet this demand, as they exhibit the mechanical properties of polymers, with an electrical conductivity typical of semiconductors. Moreover, their biocompatibility makes them promising candidates for effectively interfacing the human body. In particular, sweat analysis is very attractive to wearable technologies as perspiration is a naturally occurring process and sweat can be sampled non-invasively and continuously over time. This review discusses the role of CPs in the development of textile electrochemical sensors specifically designed for real-time sweat monitoring and the main challenges related to this topic.

Biosensors based on Organic Electrochemical Transistors (OECTs) are developed for the selective detection of glucose and lactate. The transistor architecture provides signal amplification (gain) with respect to the simple amperometric response. The biosensors are based on a poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) channel and the gate electrode is functionalised with glucose oxidase (GOx) or lactate oxidase (LOx) enzymes, which are immobilised within a Ni/Al Layered Double Hydroxide (LDH) through a one-step electrodeposition procedure. The here-designed OECT architecture allows minimising the required amount of enzyme during electrodeposition. The output signal of the biosensor is the drain current (I_d), which decreases as the analyte concentration increases. In the optimised conditions, the biosensor responds to glucose in the range of 0.1–8.0 mM with a limit of detection (LOD) of 0.02 mM. Two regimes of proportionality are observed. For concentrations lower than 1.0 mM, a linear response is obtained with a mean gain of 360, whereas for concentrations higher than 1.0 mM, I_d is proportional to the logarithm of glucose concentration, with a gain of 220. For lactate detection, the biosensor response is linear in the whole concentration range (0.05–8.0 mM). A LOD of 0.04 mM is reached, with a net gain equal to 400.

The next future strategies for improved occupational safety and health management could largely benefit from wearable and Internet of Things technologies, enabling the real-time monitoring of health-related and environmental information to the wearer, to emergency responders, and to inspectors. The aim of this study is the development of a wearable gas sensor for the detection of NH₃ at room temperature based on the organic semiconductor poly(3,4-ethylenedioxythiophene) (PEDOT), electrochemically deposited iridium oxide particles, and a hydrogel film. The hydrogel composition was finely optimised to obtain self-healing properties, as well as the desired porosity, adhesion to the substrate, and stability in humidity variations. Its chemical structure and morphology were characterised by infrared spectroscopy and scanning electron microscopy, respectively, and were found to play a key role in the transduction process and in the achievement of a reversible and selective response. The sensing properties rely on a potentiometric-like mechanism that significantly differs from most of the state-of-the-art NH₃ gas sensors and provides superior robustness to the final device. Thanks to the reliability of the analytical response, the simple two-terminal configuration and the low power consumption, the PEDOT:PSS/IrOx Ps/hydrogel sensor was realised on a flexible plastic foil and successfully tested in a wearable configuration with wireless connectivity to a smartphone. The wearable sensor showed stability to mechanical deformations and good analytical performances, with a sensitivity of 60 ± 8 μA decade⁻¹ in a wide concentration range (17–7899 ppm), which includes the safety limits set by law for NH₃ exposure.

One of the main problems of hard-to-heal wounds regards the monitoring of their healing progress. Currently, clinicians monitor the wound’s status by removing the dressing, disturbing the healing process. A relevant parameter that they need to monitor is wound moisture. Indeed, a low amount of exudate can desiccate the wound, while a high level of moisture will lead to maceration. Thus, to optimize the healing process, it is particularly important to maintain an optimum level of moisture, while limiting unnecessary dressing changes. An innovative solution to address this issue is the design of a bandage with an integrated moisture sensor. In this work, we developed a textile sensor based on a conductive polymer poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) that discriminates wound’s moisture level. PEDOT:PSS is screen printed on a gauze in a specific geometry. Exploiting its intrinsic electrochemical properties, the sensor operates in real time by monitoring impedance variations that span over several orders of magnitude between dry and wet states. The sensor is directly integrated with an RFID chip, implementing a real-time wireless monitoring. The final device results in a low-cost, user friendly, disposable and wirelessly connected patch.

In recent years, wearable technologies have attracted great attention in physical and chemical sensing applications. Wearable pressure sensors with high sensitivity in low pressure range (<10 kPa) allow touch detection for human-computer interaction and the development of artificial hands for handling objects. Conversely, pressure sensors that perform in a high pressure range (up to 100 kPa), can be used to monitor the foot pressure distribution, the hand stress during movements of heavy weights or to evaluate the cyclist’s pressure pattern on a bicycle saddle. Recently, we developed a fully textile pressure sensor based on a conductive polymer, with simple fabrication and scalable features. In this paper, we intend to provide an extensive description on how the mechanical properties of several fabrics and different piezoresistive ink formulation may have an impact in the sensor’s response during a dynamic operation mode. These results highlight the complexity of the system due to the presence of various parameters such as the fabric used, the conductive polymer solution, the operation mode and the desired pressure range. Furthermore, this work can lead to a protocol for new improvements and optimizations useful for adapting textile pressure sensors to a large variety of applications.