Maria Grazia Grazia Frigo

Dr. Maria Grazia Grazia Frigo


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 November 2022 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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ANTONIO COVIELLOANTONIO COVIELLO
ANTONIO COVIELLO
CICarmine Iacovazzo
Carmine Iacovazzo
ADAnella D’abrunzo
Anella D’abrunzo
MIMarilena Ianniello
Marilena Ianniello
MFMaria Grazia Grazia Frigo
Maria Grazia Grazia Frigo
MVmaria vargas
maria vargas
Spinal anesthesia is the best choice for caesarean delivery. This technique is characterized by a complete and predictable nerve block with a fast onset and few complications. Several intrathecal adjuvants are used in order to improve the quality and duration of anesthesia and reduce its side effects. Sixty-two patients who underwent caesarean delivery under spinal anesthesia were included in this medical records review. In this retrospective study, after adopting exclusion criteria, we assessed 24 patients who received Hyperbaric Bupivacaine 0.5% 10 mg and dexmedetomidine 10 μg (G1), and 28 patients who received an institutional standard treatment with Hyperbaric Bupivacaine 0.5% 10 mg and sufentanil 5 μg (G2). We evaluated the difference in terms of motor and sensory block, postoperative pain, and adverse effects during the first 24 h following delivery and neonatal outcome. Our study found that the sufentanil group had a significantly lower requirement for analgesia than the dexmedetomidine group. Postoperative pain, assessed with the VAS scale, was stronger in G1 than in G2 (4 ± 2 vs. 2 ± 1, p-value < 0.01). Differences between the two groups regarding the intraoperative degree of motor and sensory block, motor recovery time, and neonatal Apgar scores were not noticed. Pruritus and shivering were observed only in G2. Itching and shivering did not occur in the dexmedetomidine group. Postoperative analgesia was superior in the sufentanil group, but the incidence of side effects was higher. Adjuvant dexmedetomidine prevented postoperative shivering.

12 March 2022 in Healthcare
Verified
Journal Article
Open access
PDF file
ANTONIO COVIELLOANTONIO COVIELLO
ANTONIO COVIELLO
MVmaria vargas
maria vargas
AMannachiara marra
annachiara marra
LGLudovica Golino
Ludovica Golino
GSGabriele Saccone
Gabriele Saccone
GSGiuseppe Servillo
Giuseppe Servillo
Background: Our hospital became a referral center for COVID-19-positive obstetric patients from 1 May 2020. The aim of our study is to illustrate our management protocols for COVID-19-positive obstetric patients, to maintain safety standards for patients and healthcare workers. Methods: Women who underwent vaginal or operative delivery and induced or spontaneous abortion with a SARS-CoV-2-positive nasopharyngeal swab using real-time PCR (RT-PCR) were included in the study. Severity and onset of new symptoms were carefully monitored in the postoperative period. All the healthcare workers received a nasopharyngeal swab for SARS-CoV-2 using RT-PCR serially every five days. Results: We included 152 parturients with COVID-19 infection. None of the included women had general anesthesia, an increase of severe symptoms or onset of new symptoms. The RT-PCR test was “negative” for the healthcare workers. Conclusions: In our study, neuraxial anesthesia for parturients’ management with SARS-CoV-2 infection has been proven to be safe for patients and healthcare workers. Neuraxial anesthesia decreases aerosolization during preoxygenation, face-mask ventilation, endotracheal intubation, oral or tracheal suctioning and extubation. This anesthesia management protocol can be generalizable.

19 February 2026 in Anesthesia & Analgesia
Verified
Journal Article
Open access
ANTONIO COVIELLOANTONIO COVIELLO
ANTONIO COVIELLO
MFMaria Grazia Grazia Frigo
Maria Grazia Grazia Frigo
DCDario Cirillo
Dario Cirillo
FCFilomena Coppola
Filomena Coppola
GRGiorgio Ranieri
Giorgio Ranieri
GSGiuseppe Servillo
Giuseppe Servillo