OBJECTIVES: Vascular causes are most frequently implicated in idiopathic sudden sensorineural hearing loss (ISSHL), and the process has been reported to be associated with fibrinogens and plasma lipoproteins. The purpose of this study was to determine the relationship between serum fibrinogen and high-density lipoprotein (HDL) levels, and the ratios of fibrinogen/HDL and monocyte/HDL, and ISSHL. MATERIALS and METHODS: The present retrospective study included 116 patients with ISSHL. Treatment outcomes was categorised four groups according to Siegel’s criteria as follows: complete recovery (Group1), partial recovery (Group 2), slight recovery (Group 3), or no improvement (Group 4). Fibrinogen, HDL and monocyte levels of patients were assessed through routine blood analyses, and fibrinogen/HDL and monocyte/HDL ratios were calculated for each patient. RESULTS: Fibrinogen values were significantly lower in Group 1 than in Groups 3 and 4, whereas the values were also significantly lower in Group 2 than in Group 3. HDL values in Group 1 were significantly higher than in the other groups. Fibrinogen/HDL values were significantly lower in Group 1 than in Groups 3 and 4. However, there was no significant difference among the groups with regard to monocyte/HDL ratios. CONCLUSION: To our knowledge, this is the first study investigating the fibrinogen/HDL ratio in ISSHL in the literature. Although fibrinogen/HDL ratio might be a useful prognostic indicator for hearing recovery in patients with ISSHL, further studies with a larger patient population is required to confirm its clinical practicability and reliability. Cite this article as: Hıra İ, Yaşar M, Kaya A, Bayram A, Özcan İ. Prognostic Value of Fibrinogen/HDL Ratio in Idiopathic Sudden Sensorineural Hearing Loss. J Int Adv Otol 2021; 17(2): 91-5.

Background: Bruxism is a complex condition characterized by excessive activity of the masticatory muscles, often associated with pain, sleep disturbances, and reduced quality of life. Botulinum toxin injections into the masseter muscle have emerged as a promising treatment option. Objective: To assess the effectiveness of masseter botulinum toxin injections on bruxism severity, pain intensity, and sleep quality over a 6-month follow-up period. Methods: This prospective study involved 80 patients diagnosed with bruxism. Clinical outcomes were evaluated using the Beck Depression Inventory (BDI), Visual Analog Scale (VAS), and Pittsburgh Sleep Quality Index (PSQI) at baseline and at 1, 3, and 6 months. Repeated measures ANOVA was used for statistical analysis. Results: Significant improvements were observed in all outcome measures. BDI scores decreased from 20.8±4.3 at baseline to 4.3±1.5 at 1 month ( P <0.001), with a partial rebound at 6 months. PSQI scores showed sustained improvement from 10.0±2.3 to 2.8±1.0 at 6 months ( P <0.001). VAS scores also demonstrated significant reductions ( P =0.004). Conclusion: Masseter botulinum toxin injection provides rapid, clinically significant relief of bruxism-related symptoms with lasting benefits, particularly for sleep quality.

Background/Objectives: Allergic rhinitis (AR) is characterized by dynamic mucosal congestion, yet the nasal septal body (NSB), inferior turbinate (IT), and adjacent airway passages have rarely been assessed together. We evaluated whether AR is associated with a multilevel structural–airway pattern while limiting confounding by marked septal deviation. Methods: This retrospective cross-sectional study included 301 adults with septal deviation < 8° (163 patients with clinically diagnosed AR and 138 participants in a clinically defined non-AR comparison group). Coronal computed tomography measurements included total transverse NSB width, dominant IT width, and adjacent airway widths. Between-group differences were evaluated using effect sizes and multivariable regression adjusted for age, sex, and septal deviation angle. Correlation, interaction, and sensitivity analyses assessed structure–airway relationships. Results: Patients with AR had greater NSB width (11.92 ± 1.81 vs. 10.80 ± 1.89 mm; Hedges’ g = 0.605) and dominant IT width (12.78 ± 1.69 vs. 10.41 ± 1.83 mm; g = 1.350), together with smaller adjacent airway widths. All four primary comparisons remained significant after Holm correction and adjustment (all p < 0.001). The NSB–IT correlation (rho = 0.257) was attenuated after adjustment for AR (partial rho = 0.089; q = 0.124), whereas inverse structure–airway associations persisted. A significant AR-status × IT-width interaction was observed for medial airway width (interaction q = 0.030). Conclusions: At the time of CT, patients with AR had greater NSB and IT widths and smaller corresponding regional airway dimensions, with a larger between-group morphometric difference at the IT level. These findings support a multilevel anatomical view of the nasal airway in AR, in which the NSB and IT are best interpreted together with their adjacent airway spaces rather than as isolated structures. Their clinical relevance, however, requires validation against symptoms and objective airflow measures.

Background and Objectives: Septorhinoplasty aims to improve nasal function and appearance, but change from baseline may not fully reflect the postoperative state perceived by patients. This study compared functional gain, aesthetic gain, and residual postoperative burden in relation to long-term satisfaction after primary septorhinoplasty. Materials and Methods: This retrospective study with cross-sectional long-term assessment included 112 adults who underwent primary open septorhinoplasty (2022–2025) with at least 12 months of follow-up. Nasal obstruction was assessed via Nasal Obstruction Symptom Evaluation (NOSE) and the obstruction domain of the Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS-O), cosmetic concerns with SCHNOS-C, and satisfaction with the Rhinoplasty Outcomes Evaluation (ROE). Associations with postoperative ROE scores were examined using correlation analyses and multivariable regression with HC3 robust standard errors. Results: Median NOSE score decreased from 50 to 5 and SCHNOS-C from 28 to 0; median postoperative ROE was 23/24. In the adjusted gain-score model, each 5-point greater SCHNOS-C improvement was associated with a 0.74-point higher ROE score (95% CI, 0.29–1.18; p = 0.001), whereas NOSE improvement was not associated with ROE score (B = 0.03 per 10 points; 95% CI, −0.11 to 0.18; p = 0.649). In the residual-burden model, postoperative NOSE (B = −0.87 per 10 points; 95% CI, −1.26 to −0.48) and SCHNOS-C (B = −3.27 per 5 points; 95% CI, −4.39 to −2.15) scores were independently associated with lower ROE scores (both p < 0.001). Conclusions: Aesthetic improvement and lower residual functional and cosmetic burden were associated with greater postoperative satisfaction. These concurrent associations support assessing postoperative status alongside change scores, with caution regarding restricted score distributions and overlapping patient-reported constructs.