A literature survey and analysis was conducted to describe the epidemiology of dengue disease in Brazil reported between 2000 and 2010. The protocol was registered on PROSPERO (CRD42011001826: http://www.crd.york.ac.uk/prospero/display_record.asp?ID=CRD42011001826). Between 31 July and 4 August 2011, the published literature was searched for epidemiological studies of dengue disease, using specific search strategies for each electronic database. A total of 714 relevant citations were identified, 51 of which fulfilled the inclusion criteria. The epidemiology of dengue disease in Brazil, in this period, was characterized by increases in the geographical spread and incidence of reported cases. The overall increase in dengue disease was accompanied by a rise in the proportion of severe cases. The epidemiological pattern of dengue disease in Brazil is complex and the changes observed during this review period are likely to have been influenced by multiple factors. Several gaps in epidemiological knowledge regarding dengue disease in Brazil were identified that provide avenues for future research, in particular, studies of regional differences, genotype evolution, and age-stratified seroprevalence. PROSPERO registration number: CRD42011001826. Dengue disease is the most prevalent arthropod-borne viral disease in humans and is a global and national public health concern in Brazil. We conducted this review to consolidate and describe the existing evidence on the epidemiology of dengue disease in Brazil, between 2000 and 2011, to gauge the recent national and regional impact of dengue disease and provide a basis for setting research priorities and prevention efforts. We used well-defined methods to search and identify relevant research, according to predetermined inclusion criteria. Despite control measures, the increased territorial distribution of the mosquito vector and the co-circulation of multiple dengue virus serotypes have resulted in increases in the incidence and distribution of dengue disease. The number of disease-related hospitalizations and deaths has also increased. Efforts to control the increasing disease incidence have been unsuccessful. This review of dengue disease epidemiology will help enhance knowledge and future disease management. Despite the high volume of research retrieved, we have identified several avenues for future research, in particular studies of regional differences, genotype evolution and age-stratified seroprevalence that will improve our knowledge of dengue disease, contribute to a more accurate estimate of global disease incidence, and also inform evidence-based policies for dengue disease prevention.

Maternal dengue antibodies are considered to play a significant role in dengue pathogenesis among infants. Determining the transplacental specific antibody transfer is invaluable for establishing the optimal vaccination age among infants in endemic regions.

Dengue remains the most important arboviral disease in the Americas and a growing global public health threat. The region experienced the largest dengue epidemic in recorded history during 2023–2024, with more than 13 million reported cases in 2024 alone, reflecting the combined effects of rapid urbanization, climate variability, population mobility, persistent social inequities, and weakened vector-control programs. This review summarizes and expands on the principal discussions of the First Dengue Summit of the Dengue Initiative of the Americas, held in Cartagena, Colombia, in September 2025. Major themes included the changing epidemiology of dengue; implementation and development of new-generation vaccines, including TAK-003 and Butantan-DV; advances in digital surveillance, outbreak forecasting, and clinical management; and integrated vector-control strategies. Particular attention is given to Wolbachia-mediated population replacement, supported by evidence from a cluster-randomized trial in Indonesia and large-scale quasi-experimental evaluations in Colombia and Brazil, which show substantial and sustained reductions in dengue incidence and hospitalization. In the Aburrá Valley, Colombia, city-wide deployment in Bello, Medellín, and Itagüí was associated with reductions exceeding 90% in notified dengue incidence where Wolbachia became established. The review also examines mathematical modeling, artificial intelligence, climate-informed surveillance, and integrated public health approaches. Persistent challenges include financial sustainability, healthcare inequities, climate change, insecticide resistance, and heterogeneous surveillance and health-system capacity. Coordinated, multisectoral, sustainable strategies that integrate vaccination, vector control, surveillance, community participation, and healthcare strengthening are essential to reduce the dengue burden and improve regional resilience.

Objective To present the experience report of the Health Surveillance Department of Goiânia, Goiás, in conducting four seroepidemiological surveys aimed at estimating the seroprevalence of SARS-CoV-2 infection in 2020, describing the operational and methodological stages as well as the challenges encountered. Methods This is an experience report on the organization and implementation of four household-based seroepidemiological surveys conducted amid the rising COVID-19 transmission in 2020. The municipal health surveillance team conducted the activities by administering standardized questionnaires and collecting venous blood samples for serological testing. Results In each survey, approximately 300 public health professionals visited around 2,500 households in a single day. In total, 10,147 individuals aged 5 years and older were recruited. The main challenges involved resource and field team organization, methodological design, laboratory support, and community participation. These obstacles were overcome through external partnerships, method standardization, and a systematized organizational structure. Conclusion The experience demonstrated that, despite operational constraints, municipal health surveillance can conduct large-scale seroepidemiological surveys within a short time frame. Intersectoral mobilization and process systematization facilitated the overcoming of challenges, resulting in a replicable strategy for other communicable diseases in emergency contexts.

Dengue is considered the most important acute febrile arbovirus in the world due to its burden on morbidity and mortality of countries. Cohort studies are appropriate for understanding dengue transmission dynamics and establishing baselines prior to the adoption of new control strategies. However, these studies pose major operational challenges that tend to hinder their execution, especially in developing countries. The strategies used in implanting and conducting a cohort in Central Brazil (city of Goiania) are presented, including the approaches adopted to overcome the challenges observed. The following steps are described and discussed: defining the field work team, establishing partnerships and the recruitment of participants; the initial serosurvey; technology in field research; and monitoring and evaluation of febrile episodes. A partnership between academia and public health services was the adopted approach and participation of the Municipal Health Secretariat and the Family Health Teams was essential for the proper implementation and conduction of the study. In return, the researchers' performance favored the Health Service through surveillance and health care activities of the population. This interinstitutional experience was successful with benefits for both institutions.

To Describe the methodology used in the first risk factor survey for non-communicable diseases in Goiás, a central state of Brazil and identify differences in prevalence of risk and protective factors for chronic disease between landline and mobile phone users. A cross-sectional study. A cross-sectional study was conducted using telephone interviews via landlines and mobile phones. The Random-Digit Dialing probabilistic sampling method was used to select phone lines. The Rake method weighted the data and the hot deck technique imputed missing weight and height data. A total of 5018 individuals residing in Goiás were stratified by sex, age group, education level and health macro-regions. Operational, demographic characteristics and prevalence of risk factors were evaluated, with crude and adjusted prevalence ratios calculated using the Poisson regression model. Mobile telephony offered some operational advantages, while refusal rates were lower for landlines. Landline telephony underestimated men, adults and individuals with fewer years of schooling, while mobile's underestimated the elderly. Significant differences in prevalence were found for 16 indicators. Mobile phone users showed higher prevalence of risk factors, while landline's showed higher prevalence of protective factors. The use of both landline and mobile telephony was necessary to ensure population representativeness. However, new strategies are needed to improve participation in future surveys.