Nikolaos Pagonis

Nikolaos Pagonis


Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 November 2026 in Sensors
Verified
Journal Article
Open access
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NPNikolaos Pagonis
Nikolaos Pagonis
KPKOSTANTINOS PLOMARITIS
KOSTANTINOS PLOMARITIS
Evangelos KogiasEvangelos Kogias
Evangelos Kogias
NFNikolaos Foroglou
Nikolaos Foroglou
Ioanna ChouvardaIoanna Chouvarda
Ioanna Chouvarda
Preoperative differentiation of glioma from meningioma on MRI is important for treatment planning but depends on expert interpretation. A 3D ResNet-34 with CBAM attention was trained on four-modality MRI from 2251 BraTS 2023 patients (1801 for four-fold cross-validation; 450 held out for testing) and achieved 96% accuracy, an AUC of 0.993, and an expected calibration error of 0.0165 on the test set. For layer-wise explanation, Grad-CAM and SmoothGrad were applied at the four residual stages, and a reconstruction decoder was added to obtain full-resolution, decoder-mediated attribution at the 4 × 4 × 4 bottleneck, where standard Grad-CAM is too coarse. Four quantitative metrics gave complementary results: the decoder-assisted attribution had the highest pointing-game accuracy (80.2%) and the lowest deletion AUC, whereas Layer 1 had the highest insertion AUC and Layer 2 the highest mean faithfulness delta, with no significant faithfulness difference among Layers 1, 2, and 4. Glioma was localized by most layers, while meningioma was localized mainly through the decoder-assisted pathway. A preliminary clinical review and a normalization analysis are also reported. The decoder offers an annotation-free way to obtain full-resolution attribution from deep layers of volumetric models.